rs718907

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0075 (2249/29970,GnomAD)
A=0083 (2434/29118,TOPMED)
A=0079 (395/5008,1000G)
A=0067 (257/3854,ALSPAC)
A=0066 (246/3708,TWINSUK)
chr5:175716629 (GRCh38.p7) (5q35.2)
AD
GWASdb2
1   publication(s)
See rs on genome
132 Enhancers around
5 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.175716629C>A
GRCh37.p13 chr 5NC_000005.9:g.175143632C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.874A=0.126
1000GenomesAmericanSub694C=0.940A=0.060
1000GenomesEast AsianSub1008C=0.955A=0.045
1000GenomesEuropeSub1006C=0.917A=0.083
1000GenomesGlobalStudy-wide5008C=0.921A=0.079
1000GenomesSouth AsianSub978C=0.940A=0.060
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.933A=0.067
The Genome Aggregation DatabaseAfricanSub8708C=0.885A=0.115
The Genome Aggregation DatabaseAmericanSub838C=0.940A=0.060
The Genome Aggregation DatabaseEast AsianSub1622C=0.970A=0.030
The Genome Aggregation DatabaseEuropeSub18500C=0.939A=0.060
The Genome Aggregation DatabaseGlobalStudy-wide29970C=0.925A=0.075
The Genome Aggregation DatabaseOtherSub302C=0.930A=0.070
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.916A=0.083
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.934A=0.066
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs7189070.000378alcohol dependence20201924

eQTL of rs718907 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs718907 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5175096816175097220E067-46412
chr5175097499175097672E067-45960
chr5175097723175098086E067-45546
chr5175107014175107088E067-36544
chr5175107142175107821E067-35811
chr5175109899175109949E067-33683
chr5175113208175113380E067-30252
chr5175113665175113715E067-29917
chr5175114235175114488E067-29144
chr5175118078175118604E067-25028
chr5175119465175120650E067-22982
chr5175120699175121018E067-22614
chr5175098977175099066E068-44566
chr5175099213175099379E068-44253
chr5175099380175099444E068-44188
chr5175099685175100260E068-43372
chr5175107142175107821E068-35811
chr5175113665175113715E068-29917
chr5175114235175114488E068-29144
chr5175115404175117004E068-26628
chr5175117126175117268E068-26364
chr5175117331175117494E068-26138
chr5175118078175118604E068-25028
chr5175119465175120650E068-22982
chr5175120699175121018E068-22614
chr5175121312175121392E068-22240
chr5175121608175121759E068-21873
chr5175121771175122247E068-21385
chr5175123006175123321E068-20311
chr5175125272175125322E068-18310
chr5175137061175137111E068-6521
chr5175137250175137605E068-6027
chr5175137633175137899E068-5733
chr5175139146175139288E068-4344
chr5175173827175174226E06830195
chr5175113665175113715E069-29917
chr5175119465175120650E069-22982
chr5175120699175121018E069-22614
chr5175139146175139288E069-4344
chr5175173482175173612E06929850
chr5175173667175173754E06930035
chr5175173827175174226E06930195
chr5175174701175174779E06931069
chr5175095115175095266E070-48366
chr5175097499175097672E070-45960
chr5175097723175098086E070-45546
chr5175107014175107088E070-36544
chr5175107142175107821E070-35811
chr5175113208175113380E070-30252
chr5175113665175113715E070-29917
chr5175114235175114488E070-29144
chr5175118078175118604E070-25028
chr5175120699175121018E070-22614
chr5175121312175121392E070-22240
chr5175124780175125049E070-18583
chr5175125272175125322E070-18310
chr5175155285175155584E07011653
chr5175166833175166946E07023201
chr5175167114175167245E07023482
chr5175173827175174226E07030195
chr5175174701175174779E07031069
chr5175119465175120650E071-22982
chr5175172270175172622E07128638
chr5175173482175173612E07129850
chr5175173667175173754E07130035
chr5175173827175174226E07130195
chr5175113208175113380E072-30252
chr5175113665175113715E072-29917
chr5175114235175114488E072-29144
chr5175115404175117004E072-26628
chr5175119465175120650E072-22982
chr5175173482175173612E07229850
chr5175173667175173754E07230035
chr5175097499175097672E073-45960
chr5175097723175098086E073-45546
chr5175099685175100260E073-43372
chr5175107142175107821E073-35811
chr5175111657175111785E073-31847
chr5175115404175117004E073-26628
chr5175117126175117268E073-26364
chr5175117331175117494E073-26138
chr5175119465175120650E073-22982
chr5175137061175137111E073-6521
chr5175168693175168758E07325061
chr5175168815175168891E07325183
chr5175173482175173612E07429850
chr5175173667175173754E07430035
chr5175173827175174226E07430195
chr5175095115175095266E081-48366
chr5175099685175100260E081-43372
chr5175103057175103437E081-40195
chr5175107142175107821E081-35811
chr5175109323175109539E081-34093
chr5175109557175109864E081-33768
chr5175109899175109949E081-33683
chr5175114235175114488E081-29144
chr5175115404175117004E081-26628
chr5175117126175117268E081-26364
chr5175117331175117494E081-26138
chr5175118078175118604E081-25028
chr5175119465175120650E081-22982
chr5175120699175121018E081-22614
chr5175121312175121392E081-22240
chr5175121608175121759E081-21873
chr5175121771175122247E081-21385
chr5175162485175162584E08118853
chr5175170668175170753E08127036
chr5175170831175170953E08127199
chr5175176625175176821E08132993
chr5175177429175177951E08133797
chr5175179483175180137E08135851
chr5175180202175180281E08136570
chr5175180398175180456E08136766
chr5175180974175181425E08137342
chr5175181705175181907E08138073
chr5175107014175107088E082-36544
chr5175107142175107821E082-35811
chr5175109323175109539E082-34093
chr5175109557175109864E082-33768
chr5175109899175109949E082-33683
chr5175118078175118604E082-25028
chr5175119465175120650E082-22982
chr5175120699175121018E082-22614
chr5175121312175121392E082-22240
chr5175173827175174226E08230195
chr5175176625175176821E08232993
chr5175177429175177951E08233797
chr5175179483175180137E08235851
chr5175180202175180281E08236570
chr5175180398175180456E08236766
chr5175180974175181425E08237342
chr5175181705175181907E08238073










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr5175156102175157302E06712470
chr5175156102175157302E07012470
chr5175156102175157302E07212470
chr5175155928175156024E08212296
chr5175156102175157302E08212470