rs719871

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0100 (3005/29974,GnomAD)
T=0102 (2988/29118,TOPMED)
T=0092 (460/5008,1000G)
T=0108 (417/3854,ALSPAC)
T=0102 (380/3708,TWINSUK)
chr10:78385678 (GRCh38.p7) (10q22.3)
AD
GWASdb2
2   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.78385678C>T
GRCh37.p13 chr 10NC_000010.10:g.80145435C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.885T=0.115
1000GenomesAmericanSub694C=0.870T=0.130
1000GenomesEast AsianSub1008C=0.967T=0.033
1000GenomesEuropeSub1006C=0.899T=0.101
1000GenomesGlobalStudy-wide5008C=0.908T=0.092
1000GenomesSouth AsianSub978C=0.910T=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.892T=0.108
The Genome Aggregation DatabaseAfricanSub8716C=0.889T=0.111
The Genome Aggregation DatabaseAmericanSub838C=0.860T=0.140
The Genome Aggregation DatabaseEast AsianSub1622C=0.975T=0.025
The Genome Aggregation DatabaseEuropeSub18496C=0.901T=0.098
The Genome Aggregation DatabaseGlobalStudy-wide29974C=0.899T=0.100
The Genome Aggregation DatabaseOtherSub302C=0.830T=0.170
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.897T=0.102
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.898T=0.102
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res
19728873Otitis media: a genome-wide linkage scan with evidence of susceptibility loci within the 17q12 and 10q22.3 regions.Casselbrant MLBMC Med Genet

P-Value

SNP ID p-value Traits Study
rs7198710.00082alcohol dependence20201924

eQTL of rs719871 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs719871 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr108010822780108277E067-37158
chr108010833980108560E067-36875
chr108012595380126104E067-19331
chr108013540580135567E067-9868
chr108013560880136066E067-9369
chr108013610080136538E067-8897
chr108016581180165917E06720376
chr108018056680180626E06735131
chr108018066480181516E06735229
chr108019356680193616E06748131
chr108019363580193932E06748200
chr108009913680099410E068-46025
chr108011672480117857E068-27578
chr108012542980125935E068-19500
chr108012595380126104E068-19331
chr108013079380131211E068-14224
chr108013540580135567E068-9868
chr108013560880136066E068-9369
chr108013610080136538E068-8897
chr108016301280163146E06817577
chr108018056680180626E06835131
chr108018066480181516E06835229
chr108018163380181753E06836198
chr108018183080181880E06836395
chr108018192780182002E06836492
chr108018214480182267E06836709
chr108019244380193541E06847008
chr108019356680193616E06848131
chr108019363580193932E06848200
chr108019396180194223E06848526
chr108019432580194386E06848890
chr108019474780194797E06849312
chr108009894880099062E069-46373
chr108009913680099410E069-46025
chr108010822780108277E069-37158
chr108010833980108560E069-36875
chr108010862480108736E069-36699
chr108010875080108834E069-36601
chr108011635180116642E069-28793
chr108011672480117857E069-27578
chr108011795880118068E069-27367
chr108012178980121830E069-23605
chr108012184880121949E069-23486
chr108012197080122043E069-23392
chr108012213380122703E069-22732
chr108012526380125364E069-20071
chr108012542980125935E069-19500
chr108012595380126104E069-19331
chr108012622280126436E069-18999
chr108012653980126776E069-18659
chr108012678480127208E069-18227
chr108012807580128130E069-17305
chr108013540580135567E069-9868
chr108013560880136066E069-9369
chr108013610080136538E069-8897
chr108016581180165917E06920376
chr108016596080166031E06920525
chr108016607480166139E06920639
chr108016614180166191E06920706
chr108017576880176724E06930333
chr108018056680180626E06935131
chr108018066480181516E06935229
chr108018163380181753E06936198
chr108018183080181880E06936395
chr108018192780182002E06936492
chr108018214480182267E06936709
chr108019356680193616E06948131
chr108019363580193932E06948200
chr108019396180194223E06948526
chr108019432580194386E06948890
chr108009780180097998E070-47437
chr108009894880099062E070-46373
chr108011622980116345E070-29090
chr108011635180116642E070-28793
chr108011672480117857E070-27578
chr108011795880118068E070-27367
chr108011814080118292E070-27143
chr108011873680118786E070-26649
chr108011879080118948E070-26487
chr108011914680119257E070-26178
chr108011934480120166E070-25269
chr108012017880120228E070-25207
chr108012052980120840E070-24595
chr108012084780121188E070-24247
chr108012129680121346E070-24089
chr108012137780121417E070-24018
chr108012157080121672E070-23763
chr108012178980121830E070-23605
chr108012184880121949E070-23486
chr108012197080122043E070-23392
chr108012526380125364E070-20071
chr108012542980125935E070-19500
chr108012595380126104E070-19331
chr108012622280126436E070-18999
chr108012653980126776E070-18659
chr108012678480127208E070-18227
chr108012722980127304E070-18131
chr108012740880127468E070-17967
chr108012758080127634E070-17801
chr108012766780127766E070-17669
chr108012779780127909E070-17526
chr108012807580128130E070-17305
chr108012819480128244E070-17191
chr108012830180128341E070-17094
chr108013079380131211E070-14224
chr108013151680131570E070-13865
chr108013176680131925E070-13510
chr108013279280132895E070-12540
chr108013298180133062E070-12373
chr108013540580135567E070-9868
chr108013610080136538E070-8897
chr108013662580136822E070-8613
chr108013693480137035E070-8400
chr108013708580137171E070-8264
chr108013719380137506E070-7929
chr108013758480137655E070-7780
chr108013776080137908E070-7527
chr108014634780146492E070912
chr108016014980160292E07014714
chr108016123680162702E07015801
chr108016596080166031E07020525
chr108016640780169252E07020972
chr108016929580169438E07023860
chr108016948880169542E07024053
chr108016962680169701E07024191
chr108017945980179510E07034024
chr108018049180180557E07035056
chr108018056680180626E07035131
chr108018066480181516E07035229
chr108018163380181753E07036198
chr108018183080181880E07036395
chr108018192780182002E07036492
chr108018214480182267E07036709
chr108019085980190930E07045424
chr108019244380193541E07047008
chr108019396180194223E07048526
chr108019432580194386E07048890
chr108019474780194797E07049312
chr108019495480195062E07049519
chr108019523880195338E07049803
chr108009894880099062E071-46373
chr108009913680099410E071-46025
chr108010862480108736E071-36699
chr108010875080108834E071-36601
chr108011879080118948E071-26487
chr108011914680119257E071-26178
chr108011934480120166E071-25269
chr108012542980125935E071-19500
chr108012595380126104E071-19331
chr108012622280126436E071-18999
chr108012653980126776E071-18659
chr108012678480127208E071-18227
chr108013079380131211E071-14224
chr108013560880136066E071-9369
chr108013610080136538E071-8897
chr108013662580136822E071-8613
chr108013693480137035E071-8400
chr108013708580137171E071-8264
chr108013719380137506E071-7929
chr108013758480137655E071-7780
chr108014634780146492E071912
chr108016534580165426E07119910
chr108016544480165748E07120009
chr108016581180165917E07120376
chr108016596080166031E07120525
chr108016640780169252E07120972
chr108017576880176724E07130333
chr108018056680180626E07135131
chr108018066480181516E07135229
chr108018163380181753E07136198
chr108018183080181880E07136395
chr108018192780182002E07136492
chr108018214480182267E07136709
chr108019244380193541E07147008
chr108019356680193616E07148131
chr108019363580193932E07148200
chr108019396180194223E07148526
chr108019432580194386E07148890
chr108019474780194797E07149312
chr108019495480195062E07149519
chr108019523880195338E07149803
chr108010833980108560E072-36875
chr108010862480108736E072-36699
chr108010875080108834E072-36601
chr108012542980125935E072-19500
chr108012595380126104E072-19331
chr108012758080127634E072-17801
chr108012766780127766E072-17669
chr108012779780127909E072-17526
chr108012807580128130E072-17305
chr108012819480128244E072-17191
chr108013540580135567E072-9868
chr108013560880136066E072-9369
chr108013610080136538E072-8897
chr108014191580142021E072-3414
chr108019396180194223E07248526
chr108019432580194386E07248890
chr108019495480195062E07249519
chr108011672480117857E073-27578
chr108011795880118068E073-27367
chr108011814080118292E073-27143
chr108013540580135567E073-9868
chr108013560880136066E073-9369
chr108013610080136538E073-8897
chr108013662580136822E073-8613
chr108013693480137035E073-8400
chr108013708580137171E073-8264
chr108013719380137506E073-7929
chr108013758480137655E073-7780
chr108016484380164893E07319408
chr108016512280165239E07319687
chr108016534580165426E07319910
chr108016544480165748E07320009
chr108016581180165917E07320376
chr108016596080166031E07320525
chr108016607480166139E07320639
chr108016614180166191E07320706
chr108016640780169252E07320972
chr108018056680180626E07335131
chr108018066480181516E07335229
chr108018192780182002E07336492
chr108019244380193541E07347008
chr108019356680193616E07348131
chr108019363580193932E07348200
chr108019396180194223E07348526
chr108019432580194386E07348890
chr108019474780194797E07349312
chr108009894880099062E074-46373
chr108009913680099410E074-46025
chr108010822780108277E074-37158
chr108010833980108560E074-36875
chr108012542980125935E074-19500
chr108012595380126104E074-19331
chr108012766780127766E074-17669
chr108013560880136066E074-9369
chr108013610080136538E074-8897
chr108016627380166361E07420838
chr108016640780169252E07420972
chr108018056680180626E07435131
chr108019363580193932E07448200
chr108019396180194223E07448526
chr108019432580194386E07448890
chr108019474780194797E07449312
chr108019495480195062E07449519
chr108011010280110309E081-35126
chr108011635180116642E081-28793
chr108011672480117857E081-27578
chr108011795880118068E081-27367
chr108011814080118292E081-27143
chr108011873680118786E081-26649
chr108011879080118948E081-26487
chr108011914680119257E081-26178
chr108011934480120166E081-25269
chr108012017880120228E081-25207
chr108012052980120840E081-24595
chr108012084780121188E081-24247
chr108012360080123843E081-21592
chr108012406180124225E081-21210
chr108012429880124348E081-21087
chr108012441080124460E081-20975
chr108012449880124607E081-20828
chr108012469680124817E081-20618
chr108012484280124931E081-20504
chr108012502280125091E081-20344
chr108012512680125186E081-20249
chr108012526380125364E081-20071
chr108012542980125935E081-19500
chr108012595380126104E081-19331
chr108012622280126436E081-18999
chr108012653980126776E081-18659
chr108012678480127208E081-18227
chr108012722980127304E081-18131
chr108013079380131211E081-14224
chr108013151680131570E081-13865
chr108013176680131925E081-13510
chr108013279280132895E081-12540
chr108013298180133062E081-12373
chr108013445980134509E081-10926
chr108013452080134574E081-10861
chr108013474980134835E081-10600
chr108013488980134939E081-10496
chr108013524280135384E081-10051
chr108013540580135567E081-9868
chr108013560880136066E081-9369
chr108013610080136538E081-8897
chr108013662580136822E081-8613
chr108013693480137035E081-8400
chr108013708580137171E081-8264
chr108013719380137506E081-7929
chr108013758480137655E081-7780
chr108014025480140318E081-5117
chr108014039580140618E081-4817
chr108014080680140885E081-4550
chr108014094980141069E081-4366
chr108014114880141229E081-4206
chr108014634780146492E081912
chr108014670280146752E0811267
chr108015963980160049E08114204
chr108016014980160292E08114714
chr108016045980160528E08115024
chr108016092780160992E08115492
chr108016123680162702E08115801
chr108016301280163146E08117577
chr108016330780163357E08117872
chr108016345180163569E08118016
chr108016371180163830E08118276
chr108016387780163927E08118442
chr108016544480165748E08120009
chr108016581180165917E08120376
chr108016596080166031E08120525
chr108016607480166139E08120639
chr108016614180166191E08120706
chr108016627380166361E08120838
chr108016640780169252E08120972
chr108016929580169438E08123860
chr108017104980171099E08125614
chr108017113180171185E08125696
chr108017165780171929E08126222
chr108017219680172335E08126761
chr108017240380172618E08126968
chr108017262780173445E08127192
chr108017368080173734E08128245
chr108017376280173812E08128327
chr108017774080177812E08132305
chr108017787080177924E08132435
chr108017798980178043E08132554
chr108017818780178261E08132752
chr108017883980178969E08133404
chr108017930980179359E08133874
chr108017945980179510E08134024
chr108017958180179692E08134146
chr108017975180179824E08134316
chr108017994980179999E08134514
chr108018031780180374E08134882
chr108018049180180557E08135056
chr108018056680180626E08135131
chr108018066480181516E08135229
chr108018163380181753E08136198
chr108018183080181880E08136395
chr108018192780182002E08136492
chr108018214480182267E08136709
chr108019244380193541E08147008
chr108019356680193616E08148131
chr108019363580193932E08148200
chr108019396180194223E08148526
chr108019432580194386E08148890
chr108019474780194797E08149312
chr108019495480195062E08149519
chr108019523880195338E08149803
chr108011635180116642E082-28793
chr108011672480117857E082-27578
chr108011795880118068E082-27367
chr108011814080118292E082-27143
chr108011873680118786E082-26649
chr108011879080118948E082-26487
chr108011914680119257E082-26178
chr108011934480120166E082-25269
chr108012017880120228E082-25207
chr108012052980120840E082-24595
chr108012129680121346E082-24089
chr108012336280123433E082-22002
chr108012360080123843E082-21592
chr108012406180124225E082-21210
chr108012429880124348E082-21087
chr108012441080124460E082-20975
chr108012449880124607E082-20828
chr108012469680124817E082-20618
chr108012484280124931E082-20504
chr108012502280125091E082-20344
chr108012512680125186E082-20249
chr108012526380125364E082-20071
chr108012542980125935E082-19500
chr108012595380126104E082-19331
chr108012622280126436E082-18999
chr108012653980126776E082-18659
chr108012678480127208E082-18227
chr108012722980127304E082-18131
chr108012740880127468E082-17967
chr108012758080127634E082-17801
chr108012766780127766E082-17669
chr108012779780127909E082-17526
chr108013279280132895E082-12540
chr108013298180133062E082-12373
chr108013337280133450E082-11985
chr108013345780133605E082-11830
chr108013474980134835E082-10600
chr108013488980134939E082-10496
chr108013524280135384E082-10051
chr108013540580135567E082-9868
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chr108013719380137506E082-7929
chr108013758480137655E082-7780
chr108013776080137908E082-7527
chr108014025480140318E082-5117
chr108014039580140618E082-4817
chr108016092780160992E08215492
chr108016123680162702E08215801
chr108016596080166031E08220525
chr108016607480166139E08220639
chr108016614180166191E08220706
chr108016640780169252E08220972
chr108016929580169438E08223860
chr108017165780171929E08226222
chr108017219680172335E08226761
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chr108017406580174115E08228630
chr108017774080177812E08232305
chr108017787080177924E08232435
chr108017798980178043E08232554
chr108017883980178969E08233404
chr108017930980179359E08233874
chr108017945980179510E08234024
chr108017958180179692E08234146
chr108017975180179824E08234316
chr108017994980179999E08234514
chr108018031780180374E08234882
chr108018049180180557E08235056
chr108018056680180626E08235131
chr108018066480181516E08235229
chr108018163380181753E08236198
chr108018183080181880E08236395
chr108018192780182002E08236492
chr108018214480182267E08236709
chr108018921780189609E08243782
chr108018989480189994E08244459
chr108019356680193616E08248131
chr108019363580193932E08248200
chr108019396180194223E08248526
chr108019432580194386E08248890
chr108019474780194797E08249312
chr108019495480195062E08249519
chr108019523880195338E08249803