rs720133

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0294 (8809/29936,GnomAD)
C=0279 (8139/29118,TOPMED)
C=0336 (1684/5008,1000G)
C=0300 (1156/3854,ALSPAC)
C=0278 (1032/3708,TWINSUK)
chr8:116904042 (GRCh38.p7) (8q24.11)
AD
GWASdb2
1   publication(s)
See rs on genome
160 Enhancers around
31 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.116904042T>C
GRCh37.p13 chr 8NC_000008.10:g.117916281T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.772C=0.228
1000GenomesAmericanSub694T=0.730C=0.270
1000GenomesEast AsianSub1008T=0.615C=0.385
1000GenomesEuropeSub1006T=0.710C=0.290
1000GenomesGlobalStudy-wide5008T=0.664C=0.336
1000GenomesSouth AsianSub978T=0.470C=0.530
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.700C=0.300
The Genome Aggregation DatabaseAfricanSub8712T=0.752C=0.248
The Genome Aggregation DatabaseAmericanSub834T=0.710C=0.290
The Genome Aggregation DatabaseEast AsianSub1614T=0.635C=0.365
The Genome Aggregation DatabaseEuropeSub18474T=0.689C=0.310
The Genome Aggregation DatabaseGlobalStudy-wide29936T=0.705C=0.294
The Genome Aggregation DatabaseOtherSub302T=0.740C=0.260
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.720C=0.279
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.722C=0.278
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs7201330.000032alcoholismpha002891
rs7201330.000032alcohol dependence20201924

eQTL of rs720133 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs720133 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr8117873461117873541E067-42740
chr8117877187117877306E067-38975
chr8117877480117877662E067-38619
chr8117878123117878173E067-38108
chr8117878204117878254E067-38027
chr8117878273117878323E067-37958
chr8117878451117878491E067-37790
chr8117878621117878738E067-37543
chr8117878834117879027E067-37254
chr8117879099117879322E067-36959
chr8117879381117879457E067-36824
chr8117879491117879554E067-36727
chr8117879687117879772E067-36509
chr8117916001117916074E067-207
chr8117916142117916222E067-59
chr8117916252117916320E0670
chr8117957466117958788E06741185
chr8117873461117873541E068-42740
chr8117875735117876148E068-40133
chr8117878204117878254E068-38027
chr8117878273117878323E068-37958
chr8117878451117878491E068-37790
chr8117878621117878738E068-37543
chr8117878834117879027E068-37254
chr8117879099117879322E068-36959
chr8117879381117879457E068-36824
chr8117879491117879554E068-36727
chr8117879687117879772E068-36509
chr8117884467117884517E068-31764
chr8117899642117900201E068-16080
chr8117957466117958788E06841185
chr8117958793117958843E06842512
chr8117872574117872678E069-43603
chr8117872711117872764E069-43517
chr8117873461117873541E069-42740
chr8117873563117873869E069-42412
chr8117877187117877306E069-38975
chr8117877480117877662E069-38619
chr8117878123117878173E069-38108
chr8117878204117878254E069-38027
chr8117878273117878323E069-37958
chr8117878451117878491E069-37790
chr8117878621117878738E069-37543
chr8117878834117879027E069-37254
chr8117879099117879322E069-36959
chr8117879381117879457E069-36824
chr8117879491117879554E069-36727
chr8117879687117879772E069-36509
chr8117880283117880553E069-35728
chr8117883007117883348E069-32933
chr8117883424117883474E069-32807
chr8117883902117883979E069-32302
chr8117884019117884157E069-32124
chr8117884467117884517E069-31764
chr8117916001117916074E069-207
chr8117916142117916222E069-59
chr8117916252117916320E0690
chr8117878621117878738E070-37543
chr8117878834117879027E070-37254
chr8117880986117881049E070-35232
chr8117881130117881199E070-35082
chr8117881545117881812E070-34469
chr8117881968117882060E070-34221
chr8117882844117882998E070-33283
chr8117883007117883348E070-32933
chr8117938713117939872E07022432
chr8117957466117958788E07041185
chr8117958793117958843E07042512
chr8117959134117959184E07042853
chr8117959383117959505E07043102
chr8117871858117872021E071-44260
chr8117872574117872678E071-43603
chr8117872711117872764E071-43517
chr8117873563117873869E071-42412
chr8117874131117874204E071-42077
chr8117875735117876148E071-40133
chr8117877480117877662E071-38619
chr8117878123117878173E071-38108
chr8117878204117878254E071-38027
chr8117878273117878323E071-37958
chr8117878451117878491E071-37790
chr8117878621117878738E071-37543
chr8117878834117879027E071-37254
chr8117879687117879772E071-36509
chr8117880283117880553E071-35728
chr8117883007117883348E071-32933
chr8117883424117883474E071-32807
chr8117883902117883979E071-32302
chr8117884019117884157E071-32124
chr8117884467117884517E071-31764
chr8117899642117900201E071-16080
chr8117916001117916074E071-207
chr8117916142117916222E071-59
chr8117916252117916320E0710
chr8117872574117872678E072-43603
chr8117872711117872764E072-43517
chr8117873563117873869E072-42412
chr8117874131117874204E072-42077
chr8117875735117876148E072-40133
chr8117877187117877306E072-38975
chr8117877480117877662E072-38619
chr8117878123117878173E072-38108
chr8117878204117878254E072-38027
chr8117878273117878323E072-37958
chr8117878451117878491E072-37790
chr8117878621117878738E072-37543
chr8117880283117880553E072-35728
chr8117884467117884517E072-31764
chr8117915798117915852E072-429
chr8117916001117916074E072-207
chr8117916142117916222E072-59
chr8117878204117878254E073-38027
chr8117878273117878323E073-37958
chr8117878451117878491E073-37790
chr8117878621117878738E073-37543
chr8117879099117879322E073-36959
chr8117880283117880553E073-35728
chr8117882844117882998E073-33283
chr8117883007117883348E073-32933
chr8117957466117958788E07341185
chr8117872574117872678E074-43603
chr8117872711117872764E074-43517
chr8117873461117873541E074-42740
chr8117873563117873869E074-42412
chr8117874131117874204E074-42077
chr8117875735117876148E074-40133
chr8117877187117877306E074-38975
chr8117877480117877662E074-38619
chr8117878123117878173E074-38108
chr8117878204117878254E074-38027
chr8117878273117878323E074-37958
chr8117878451117878491E074-37790
chr8117878621117878738E074-37543
chr8117878834117879027E074-37254
chr8117915798117915852E074-429
chr8117916001117916074E074-207
chr8117916142117916222E074-59
chr8117916252117916320E0740
chr8117943482117943818E07427201
chr8117957466117958788E07441185
chr8117880986117881049E081-35232
chr8117881130117881199E081-35082
chr8117881545117881812E081-34469
chr8117881968117882060E081-34221
chr8117883007117883348E081-32933
chr8117883424117883474E081-32807
chr8117957466117958788E08141185
chr8117958793117958843E08142512
chr8117879491117879554E082-36727
chr8117879687117879772E082-36509
chr8117880283117880553E082-35728
chr8117881545117881812E082-34469
chr8117881968117882060E082-34221
chr8117883007117883348E082-32933
chr8117883424117883474E082-32807
chr8117883902117883979E082-32302
chr8117884019117884157E082-32124
chr8117884467117884517E082-31764
chr8117957466117958788E08241185
chr8117958793117958843E08242512










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr8117884803117886257E067-30024
chr8117886268117887699E067-28582
chr8117950157117951101E06733876
chr8117884803117886257E068-30024
chr8117886268117887699E068-28582
chr8117950157117951101E06833876
chr8117884803117886257E069-30024
chr8117886268117887699E069-28582
chr8117950157117951101E06933876
chr8117884803117886257E070-30024
chr8117886268117887699E070-28582
chr8117950157117951101E07033876
chr8117884803117886257E071-30024
chr8117886268117887699E071-28582
chr8117950157117951101E07133876
chr8117884803117886257E072-30024
chr8117886268117887699E072-28582
chr8117950157117951101E07233876
chr8117884803117886257E073-30024
chr8117886268117887699E073-28582
chr8117950157117951101E07333876
chr8117884803117886257E074-30024
chr8117886268117887699E074-28582
chr8117950157117951101E07433876
chr8117884803117886257E081-30024
chr8117886268117887699E081-28582
chr8117887854117887894E081-28387
chr8117887989117888050E081-28231
chr8117884803117886257E082-30024
chr8117886268117887699E082-28582
chr8117950157117951101E08233876