rs7203180

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0080 (2406/29952,GnomAD)
T=0114 (3328/29118,TOPMED)
T=0122 (613/5008,1000G)
T=0004 (15/3854,ALSPAC)
T=0006 (23/3708,TWINSUK)
chr16:3420827 (GRCh38.p7) (16p13.3)
AD
GWASdb2
1   publication(s)
See rs on genome
192 Enhancers around
38 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.3420827C>T
GRCh37.p13 chr 16NC_000016.9:g.3470827C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.716T=0.284
1000GenomesAmericanSub694C=0.970T=0.030
1000GenomesEast AsianSub1008C=0.873T=0.127
1000GenomesEuropeSub1006C=0.996T=0.004
1000GenomesGlobalStudy-wide5008C=0.878T=0.122
1000GenomesSouth AsianSub978C=0.910T=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.996T=0.004
The Genome Aggregation DatabaseAfricanSub8708C=0.762T=0.238
The Genome Aggregation DatabaseAmericanSub838C=0.970T=0.030
The Genome Aggregation DatabaseEast AsianSub1618C=0.905T=0.095
The Genome Aggregation DatabaseEuropeSub18486C=0.992T=0.007
The Genome Aggregation DatabaseGlobalStudy-wide29952C=0.919T=0.080
The Genome Aggregation DatabaseOtherSub302C=0.970T=0.030
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.885T=0.114
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.994T=0.006
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs72031800.000574alcohol consumption (maxi-drinks)24277619

eQTL of rs7203180 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7203180 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1634528133452869E067-17958
chr1634529143452977E067-17850
chr1634948803494944E06724053
chr1635059853506431E06735158
chr1635102483510352E06739421
chr1635103933510480E06739566
chr1635106443510743E06739817
chr1635107863510853E06739959
chr1635108563511604E06740029
chr1635116683511756E06740841
chr1635125563512614E06741729
chr1635127613512812E06741934
chr1635155923515642E06744765
chr1635156633515703E06744836
chr1635159893516039E06745162
chr1635164203516511E06745593
chr1635165633516698E06745736
chr1635167193516769E06745892
chr1635168543517165E06746027
chr1635173863517525E06746559
chr1635176063517660E06746779
chr1635178823517950E06747055
chr1635180033518340E06747176
chr1635184143518537E06747587
chr1635185523518656E06747725
chr1635186623518739E06747835
chr1634528133452869E068-17958
chr1634529143452977E068-17850
chr1634948803494944E06824053
chr1635059853506431E06835158
chr1635064713506786E06835644
chr1635102483510352E06839421
chr1635103933510480E06839566
chr1635106443510743E06839817
chr1635107863510853E06839959
chr1635108563511604E06840029
chr1635116683511756E06840841
chr1635164203516511E06845593
chr1635165633516698E06845736
chr1635167193516769E06845892
chr1635168543517165E06846027
chr1635173863517525E06846559
chr1635176063517660E06846779
chr1635178823517950E06847055
chr1635180033518340E06847176
chr1635184143518537E06847587
chr1635185523518656E06847725
chr1635186623518739E06847835
chr1634498993449949E069-20878
chr1634948803494944E06924053
chr1634950823495122E06924255
chr1634951733495276E06924346
chr1635059853506431E06935158
chr1635064713506786E06935644
chr1635102483510352E06939421
chr1635103933510480E06939566
chr1635106443510743E06939817
chr1635107863510853E06939959
chr1635108563511604E06940029
chr1635116683511756E06940841
chr1635125563512614E06941729
chr1635127613512812E06941934
chr1635156633515703E06944836
chr1635159893516039E06945162
chr1635164203516511E06945593
chr1635165633516698E06945736
chr1635167193516769E06945892
chr1635168543517165E06946027
chr1635173863517525E06946559
chr1635176063517660E06946779
chr1635178823517950E06947055
chr1635180033518340E06947176
chr1635184143518537E06947587
chr1635185523518656E06947725
chr1635186623518739E06947835
chr1634528133452869E070-17958
chr1634529143452977E070-17850
chr1634948803494944E07024053
chr1634950823495122E07024255
chr1634951733495276E07024346
chr1635106443510743E07039817
chr1635107863510853E07039959
chr1635108563511604E07040029
chr1634498993449949E071-20878
chr1634948803494944E07124053
chr1634950823495122E07124255
chr1634951733495276E07124346
chr1635059853506431E07135158
chr1635102483510352E07139421
chr1635103933510480E07139566
chr1635106443510743E07139817
chr1635107863510853E07139959
chr1635108563511604E07140029
chr1635116683511756E07140841
chr1635125563512614E07141729
chr1635143373514682E07143510
chr1635148153514921E07143988
chr1635164203516511E07145593
chr1635165633516698E07145736
chr1635167193516769E07145892
chr1635168543517165E07146027
chr1635173863517525E07146559
chr1635176063517660E07146779
chr1635178823517950E07147055
chr1635184143518537E07147587
chr1634487113448751E072-22076
chr1634528133452869E072-17958
chr1634529143452977E072-17850
chr1634542443454309E072-16518
chr1634812243481278E07210397
chr1634948803494944E07224053
chr1635046963504839E07233869
chr1635048633504997E07234036
chr1635059853506431E07235158
chr1635064713506786E07235644
chr1635102483510352E07239421
chr1635103933510480E07239566
chr1635108563511604E07240029
chr1635143373514682E07243510
chr1635148153514921E07243988
chr1635155923515642E07244765
chr1635156633515703E07244836
chr1635159893516039E07245162
chr1635164203516511E07245593
chr1635165633516698E07245736
chr1635167193516769E07245892
chr1635168543517165E07246027
chr1635173863517525E07246559
chr1635176063517660E07246779
chr1634528133452869E073-17958
chr1634529143452977E073-17850
chr1635059853506431E07335158
chr1635064713506786E07335644
chr1635103933510480E07339566
chr1635106443510743E07339817
chr1635107863510853E07339959
chr1635108563511604E07340029
chr1635116683511756E07340841
chr1635148153514921E07343988
chr1635155923515642E07344765
chr1635156633515703E07344836
chr1635159893516039E07345162
chr1635164203516511E07345593
chr1635165633516698E07345736
chr1635167193516769E07345892
chr1635168543517165E07346027
chr1635173863517525E07346559
chr1635184143518537E07347587
chr1635185523518656E07347725
chr1635186623518739E07347835
chr1634528133452869E074-17958
chr1634529143452977E074-17850
chr1634535783453618E074-17209
chr1634948803494944E07424053
chr1635046963504839E07433869
chr1635048633504997E07434036
chr1635059853506431E07435158
chr1635064713506786E07435644
chr1635102483510352E07439421
chr1635103933510480E07439566
chr1635106443510743E07439817
chr1635107863510853E07439959
chr1635108563511604E07440029
chr1635143373514682E07443510
chr1635148153514921E07443988
chr1635152833515350E07444456
chr1635155923515642E07444765
chr1635156633515703E07444836
chr1635159893516039E07445162
chr1635164203516511E07445593
chr1635165633516698E07445736
chr1635167193516769E07445892
chr1635168543517165E07446027
chr1635173863517525E07446559
chr1635176063517660E07446779
chr1635178823517950E07447055
chr1635180033518340E07447176
chr1635184143518537E07447587
chr1635185523518656E07447725
chr1635186623518739E07447835
chr1634498993449949E081-20878
chr1635064713506786E08135644
chr1635102483510352E08139421
chr1635103933510480E08139566
chr1635064713506786E08235644
chr1635156633515703E08244836
chr1635159893516039E08245162
chr1635164203516511E08245593
chr1635165633516698E08245736
chr1635180033518340E08247176
chr1635184143518537E08247587
chr1635185523518656E08247725










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1634501983452435E067-18392
chr1634814783481647E06710651
chr1634816613482274E06710834
chr1634823363482386E06711509
chr1634926973494414E06721870
chr1634501983452435E068-18392
chr1634814783481647E06810651
chr1634816613482274E06810834
chr1634823363482386E06811509
chr1634926973494414E06821870
chr1634501983452435E069-18392
chr1634816613482274E06910834
chr1634926973494414E06921870
chr1634501983452435E070-18392
chr1634816613482274E07010834
chr1634823363482386E07011509
chr1634926973494414E07021870
chr1634501983452435E071-18392
chr1634926973494414E07121870
chr1634501983452435E072-18392
chr1634816613482274E07210834
chr1634823363482386E07211509
chr1634926973494414E07221870
chr1634501983452435E073-18392
chr1634823363482386E07311509
chr1634926973494414E07321870
chr1634501983452435E074-18392
chr1634814783481647E07410651
chr1634816613482274E07410834
chr1634823363482386E07411509
chr1634926973494414E07421870
chr1634501983452435E081-18392
chr1634926973494414E08121870
chr1634501983452435E082-18392
chr1634814783481647E08210651
chr1634816613482274E08210834
chr1634823363482386E08211509
chr1634926973494414E08221870