rs7256985

Homo sapiens
G>T
CYP4F8 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0470 (14065/29916,GnomAD)
T=0446 (13005/29118,TOPMED)
T=0389 (1948/5008,1000G)
G==0460 (1772/3854,ALSPAC)
G==0463 (1715/3708,TWINSUK)
chr19:15621260 (GRCh38.p7) (19p13.12)
AD
GWASdb2
1   publication(s)
See rs on genome
15 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 19NC_000019.10:g.15621260G>T
GRCh37.p13 chr 19NC_000019.9:g.15732070G>T
CYP4F8 RefSeqGeneNG_008068.1:g.11043G>T

Gene: CYP4F8, cytochrome P450 family 4 subfamily F member 8(plus strand)

Molecule type Change Amino acid[Codon] SO Term
CYP4F8 transcriptNM_007253.3:c.N/AIntron Variant
CYP4F8 transcript variant X1XM_017026232.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.607T=0.393
1000GenomesAmericanSub694G=0.660T=0.340
1000GenomesEast AsianSub1008G=0.747T=0.253
1000GenomesEuropeSub1006G=0.461T=0.539
1000GenomesGlobalStudy-wide5008G=0.611T=0.389
1000GenomesSouth AsianSub978G=0.600T=0.400
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.460T=0.540
The Genome Aggregation DatabaseAfricanSub8704G=0.626T=0.374
The Genome Aggregation DatabaseAmericanSub836G=0.650T=0.350
The Genome Aggregation DatabaseEast AsianSub1616G=0.732T=0.268
The Genome Aggregation DatabaseEuropeSub18460G=0.461T=0.538
The Genome Aggregation DatabaseGlobalStudy-wide29916G=0.529T=0.470
The Genome Aggregation DatabaseOtherSub300G=0.530T=0.470
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.553T=0.446
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.463T=0.537
PMID Title Author Journal
23953852Genome-wide association studies of maximum number of drinks.Pan YJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs72569854.22E-05alcohol consumption23953852

eQTL of rs7256985 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7256985 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr191575092415752286E06918854
chr191575236915752419E06920299
chr191575271315752763E06920643
chr191572543915725567E070-6503
chr191572568215725732E070-6338
chr191575092415752286E07218854
chr191573970615739837E0737636
chr191573995315740017E0737883
chr191574580915746528E07313739
chr191574694215747176E07314872
chr191575069915750770E07318629
chr191575092415752286E07318854
chr191575236915752419E07320299
chr191573995315740017E0817883
chr191574006015740566E0817990