rs72681920

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0078 (2337/29966,GnomAD)
A=0082 (2415/29118,TOPMED)
A=0119 (596/5008,1000G)
A=0064 (248/3854,ALSPAC)
A=0070 (259/3708,TWINSUK)
chr4:99369122 (GRCh38.p7) (4q23)
AD
GWASCatalog
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.99369122C>A
GRCh37.p13 chr 4NC_000004.11:g.100290279C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.945A=0.055
1000GenomesAmericanSub694C=0.640A=0.360
1000GenomesEast AsianSub1008C=0.841A=0.159
1000GenomesEuropeSub1006C=0.920A=0.080
1000GenomesGlobalStudy-wide5008C=0.881A=0.119
1000GenomesSouth AsianSub978C=0.960A=0.040
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.936A=0.064
The Genome Aggregation DatabaseAfricanSub8728C=0.940A=0.060
The Genome Aggregation DatabaseAmericanSub836C=0.680A=0.320
The Genome Aggregation DatabaseEast AsianSub1612C=0.822A=0.178
The Genome Aggregation DatabaseEuropeSub18488C=0.935A=0.064
The Genome Aggregation DatabaseGlobalStudy-wide29966C=0.922A=0.078
The Genome Aggregation DatabaseOtherSub302C=0.780A=0.220
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.917A=0.082
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.930A=0.070
PMID Title Author Journal
24166409Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs726819201E-06alcohol dependence24166409

eQTL of rs72681920 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs72681920 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr4100245602100245886E068-44393
chr4100244954100245162E073-45117
chr4100245344100245493E073-44786