SNP Detail Info-rs72737330

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.216600151T>C
GRCh37.p13 chr 1	NC_000001.10:g.216773493T>C
ESRRG RefSeqGene	NG_029784.1:g.542605A>G

Gene: ESRRG, estrogen related receptor gamma(minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
ESRRG transcript variant 4	NM_001134285.2:c.	N/A	Intron Variant
ESRRG transcript variant 6	NM_001243505.1:c.	N/A	Intron Variant
ESRRG transcript variant 7	NM_001243506.1:c.	N/A	Intron Variant
ESRRG transcript variant 8	NM_001243507.1:c.	N/A	Intron Variant
ESRRG transcript variant 9	NM_001243509.1:c.	N/A	Intron Variant
ESRRG transcript variant 10	NM_001243510.2:c.	N/A	Intron Variant
ESRRG transcript variant 11	NM_001243511.2:c.	N/A	Intron Variant
ESRRG transcript variant 12	NM_001243512.1:c.	N/A	Intron Variant
ESRRG transcript variant 13	NM_001243513.1:c.	N/A	Intron Variant
ESRRG transcript variant 14	NM_001243514.1:c.	N/A	Intron Variant
ESRRG transcript variant 15	NM_001243515.1:c.	N/A	Intron Variant
ESRRG transcript variant 16	NM_001243518.1:c.	N/A	Intron Variant
ESRRG transcript variant 17	NM_001243519.1:c.	N/A	Intron Variant
ESRRG transcript variant 1	NM_001438.3:c.	N/A	Intron Variant
ESRRG transcript variant 2	NM_206594.2:c.	N/A	Intron Variant
ESRRG transcript variant 3	NM_206595.2:c.	N/A	Intron Variant
ESRRG transcript variant X2	XM_011509265.2:c.	N/A	Intron Variant
ESRRG transcript variant X7	XM_011509266.2:c.	N/A	Intron Variant
ESRRG transcript variant X8	XM_011509267.1:c.	N/A	Intron Variant
ESRRG transcript variant X9	XM_011509268.2:c.	N/A	Intron Variant
ESRRG transcript variant X10	XM_011509269.2:c.	N/A	Intron Variant
ESRRG transcript variant X11	XM_011509270.1:c.	N/A	Intron Variant
ESRRG transcript variant X15	XM_011509271.2:c.	N/A	Intron Variant
ESRRG transcript variant X23	XM_011509274.1:c.	N/A	Intron Variant
ESRRG transcript variant X29	XM_011509275.1:c.	N/A	Intron Variant
ESRRG transcript variant X22	XM_011509276.1:c.	N/A	Intron Variant
ESRRG transcript variant X28	XM_011509277.1:c.	N/A	Intron Variant
ESRRG transcript variant X30	XM_011509278.1:c.	N/A	Intron Variant
ESRRG transcript variant X27	XM_011509279.1:c.	N/A	Intron Variant
ESRRG transcript variant X31	XM_011509280.2:c.	N/A	Intron Variant
ESRRG transcript variant X1	XM_017000621.1:c.	N/A	Intron Variant
ESRRG transcript variant X3	XM_017000622.1:c.	N/A	Intron Variant
ESRRG transcript variant X4	XM_017000623.1:c.	N/A	Intron Variant
ESRRG transcript variant X5	XM_017000624.1:c.	N/A	Intron Variant
ESRRG transcript variant X6	XM_017000625.1:c.	N/A	Intron Variant
ESRRG transcript variant X11	XM_017000626.1:c.	N/A	Intron Variant
ESRRG transcript variant X12	XM_017000627.1:c.	N/A	Intron Variant
ESRRG transcript variant X13	XM_017000628.1:c.	N/A	Intron Variant
ESRRG transcript variant X15	XM_017000629.1:c.	N/A	Intron Variant
ESRRG transcript variant X14	XM_017000630.1:c.	N/A	Intron Variant
ESRRG transcript variant X18	XM_017000631.1:c.	N/A	Intron Variant
ESRRG transcript variant X19	XM_017000632.1:c.	N/A	Intron Variant
ESRRG transcript variant X21	XM_017000633.1:c.	N/A	Intron Variant
ESRRG transcript variant X21	XM_017000634.1:c.	N/A	Intron Variant
ESRRG transcript variant X24	XM_017000635.1:c.	N/A	Intron Variant
ESRRG transcript variant X25	XM_017000636.1:c.	N/A	Intron Variant
ESRRG transcript variant X26	XM_017000637.1:c.	N/A	Intron Variant
ESRRG transcript variant X32	XM_017000638.1:c.	N/A	Intron Variant
ESRRG transcript variant X36	XM_017000639.1:c.	N/A	Intron Variant
ESRRG transcript variant X34	XM_017000640.1:c.	N/A	Intron Variant
ESRRG transcript variant X37	XM_017000641.1:c.	N/A	Intron Variant
ESRRG transcript variant X36	XM_017000642.1:c.	N/A	Intron Variant
ESRRG transcript variant X37	XM_017000643.1:c.	N/A	Intron Variant
ESRRG transcript variant X38	XM_017000644.1:c.	N/A	Intron Variant
ESRRG transcript variant X39	XM_017000645.1:c.	N/A	Intron Variant
ESRRG transcript variant X40	XM_017000646.1:c.	N/A	Intron Variant
ESRRG transcript variant X41	XM_017000647.1:c.	N/A	Intron Variant
ESRRG transcript variant X42	XM_017000648.1:c.	N/A	Intron Variant
ESRRG transcript variant X43	XM_017000649.1:c.	N/A	Intron Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.971	C=0.029
1000Genomes	American	Sub	694	T=0.890	C=0.110
1000Genomes	East Asian	Sub	1008	T=0.999	C=0.001
1000Genomes	Europe	Sub	1006	T=0.792	C=0.208
1000Genomes	Global	Study-wide	5008	T=0.907	C=0.093
1000Genomes	South Asian	Sub	978	T=0.850	C=0.150
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.801	C=0.199
The Genome Aggregation Database	African	Sub	8734	T=0.946	C=0.054
The Genome Aggregation Database	American	Sub	834	T=0.860	C=0.140
The Genome Aggregation Database	East Asian	Sub	1620	T=0.999	C=0.001
The Genome Aggregation Database	Europe	Sub	18482	T=0.798	C=0.201
The Genome Aggregation Database	Global	Study-wide	29970	T=0.853	C=0.146
The Genome Aggregation Database	Other	Sub	300	T=0.780	C=0.220
Trans-Omics for Precision Medicine	Global	Study-wide	29116	T=0.878	C=0.122
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.791	C=0.209

PMID	Title	Author	Journal
29071344	Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.	Zhou H	JAMA Psychiatry

P-Value

SNP ID	p-value	Traits	Study
rs72737330	9E-07	alcohol dependence	29071344

eQTL of rs72737330 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs72737330 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	216769252	216769302	E067	-4191
chr1	216773307	216773758	E068	0
chr1	216773307	216773758	E069	0
chr1	216773307	216773758	E070	0
chr1	216803388	216803438	E070	29895
chr1	216803847	216803946	E070	30354
chr1	216804014	216804174	E070	30521
chr1	216804550	216804600	E070	31057
chr1	216807943	216808053	E070	34450
chr1	216808102	216808207	E070	34609
chr1	216773307	216773758	E071	0
chr1	216773307	216773758	E073	0
chr1	216773307	216773758	E074	0
chr1	216725198	216725272	E081	-48221
chr1	216803847	216803946	E081	30354
chr1	216804014	216804174	E081	30521

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr1	216773940	216775098	E067	447
chr1	216775261	216775311	E067	1768
chr1	216773940	216775098	E068	447
chr1	216773940	216775098	E069	447
chr1	216773940	216775098	E070	447
chr1	216773940	216775098	E071	447
chr1	216775261	216775311	E071	1768
chr1	216773940	216775098	E072	447
chr1	216775261	216775311	E072	1768
chr1	216773940	216775098	E073	447
chr1	216773940	216775098	E074	447
chr1	216773940	216775098	E082	447

rs72737330

Genomic Coordinates

Gene: ESRRG, estrogen related receptor gamma(minus strand)

Population Frequency

P-Value

eQTL of rs72737330 in Brain tissues (GTEx Analysis Release V7)

meQTL of rs72737330 in Fetal Brain

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)

Promoter Annotation (GRCh37.p13)