rs7276036

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

APP : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0306 (9169/29920,GnomAD)
A=0360 (10488/29118,TOPMED)
A=0378 (1891/5008,1000G)
A=0223 (859/3854,ALSPAC)
A=0240 (891/3708,TWINSUK)

Position: chr21:25989391 (GRCh38.p7) (21q21.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 828 Enhancers around

Promoter: 21 Promoters around

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 21	NC_000021.9:g.25989391G>A
GRCh37.p13 chr 21	NC_000021.8:g.27361704G>A
APP RefSeqGene	NG_007376.1:g.186429C>T

Gene: APP, amyloid beta precursor protein(minus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
APP transcript variant 1	NM_000484.3:c.	N/A	Intron Variant
APP transcript variant 4	NM_001136016.3:c.	N/A	Intron Variant
APP transcript variant 5	NM_001136129.2:c.	N/A	Intron Variant
APP transcript variant 6	NM_001136130.2:c.	N/A	Intron Variant
APP transcript variant 7	NM_001136131.2:c.	N/A	Intron Variant
APP transcript variant 8	NM_001204301.1:c.	N/A	Intron Variant
APP transcript variant 9	NM_001204302.1:c.	N/A	Intron Variant
APP transcript variant 10	NM_001204303.1:c.	N/A	Intron Variant
APP transcript variant 2	NM_201413.2:c.	N/A	Intron Variant
APP transcript variant 3	NM_201414.2:c.	N/A	Intron Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.448	A=0.552
1000Genomes	American	Sub	694	G=0.720	A=0.280
1000Genomes	East Asian	Sub	1008	G=0.690	A=0.310
1000Genomes	Europe	Sub	1006	G=0.775	A=0.225
1000Genomes	Global	Study-wide	5008	G=0.622	A=0.378
1000Genomes	South Asian	Sub	978	G=0.560	A=0.440
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.777	A=0.223
The Genome Aggregation Database	African	Sub	8706	G=0.511	A=0.489
The Genome Aggregation Database	American	Sub	834	G=0.700	A=0.300
The Genome Aggregation Database	East Asian	Sub	1620	G=0.665	A=0.335
The Genome Aggregation Database	Europe	Sub	18458	G=0.779	A=0.220
The Genome Aggregation Database	Global	Study-wide	29920	G=0.693	A=0.306
The Genome Aggregation Database	Other	Sub	302	G=0.820	A=0.180
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.639	A=0.360
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.760	A=0.240

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

P-Value

SNP ID	p-value	Traits	Study
rs7276036	0.000276	alcohol dependence	20201924

eQTL of rs7276036 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs7276036 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr21	27313240	27313307	E067	-48397
chr21	27314389	27314433	E067	-47271
chr21	27314555	27314842	E067	-46862
chr21	27314933	27315045	E067	-46659
chr21	27316073	27316142	E067	-45562
chr21	27316283	27316352	E067	-45352
chr21	27316403	27316466	E067	-45238
chr21	27316518	27316657	E067	-45047
chr21	27316739	27316815	E067	-44889
chr21	27317022	27317484	E067	-44220
chr21	27322026	27322757	E067	-38947
chr21	27325648	27325715	E067	-35989
chr21	27326003	27326394	E067	-35310
chr21	27326649	27327236	E067	-34468
chr21	27329154	27329217	E067	-32487
chr21	27329468	27329575	E067	-32129
chr21	27329673	27329985	E067	-31719
chr21	27332451	27332511	E067	-29193
chr21	27332749	27333279	E067	-28425
chr21	27337307	27337494	E067	-24210
chr21	27339208	27339548	E067	-22156
chr21	27339845	27340417	E067	-21287
chr21	27341840	27341903	E067	-19801
chr21	27341904	27341987	E067	-19717
chr21	27343215	27343259	E067	-18445
chr21	27343742	27343792	E067	-17912
chr21	27344084	27344144	E067	-17560
chr21	27349101	27349151	E067	-12553
chr21	27349304	27349423	E067	-12281
chr21	27349642	27349698	E067	-12006
chr21	27350004	27350091	E067	-11613
chr21	27350715	27350759	E067	-10945
chr21	27352275	27352506	E067	-9198
chr21	27352684	27352856	E067	-8848
chr21	27352995	27353450	E067	-8254
chr21	27354622	27354707	E067	-6997
chr21	27354726	27354770	E067	-6934
chr21	27354984	27355034	E067	-6670
chr21	27355653	27355779	E067	-5925
chr21	27355860	27355938	E067	-5766
chr21	27356031	27356504	E067	-5200
chr21	27359379	27359530	E067	-2174
chr21	27359532	27359576	E067	-2128
chr21	27359981	27360073	E067	-1631
chr21	27360115	27360169	E067	-1535
chr21	27360223	27360316	E067	-1388
chr21	27360343	27360391	E067	-1313
chr21	27360423	27360535	E067	-1169
chr21	27361497	27361586	E067	-118
chr21	27361819	27361862	E067	115
chr21	27365882	27366131	E067	4178
chr21	27366751	27366834	E067	5047
chr21	27366945	27367356	E067	5241
chr21	27367659	27368066	E067	5955
chr21	27368520	27368636	E067	6816
chr21	27368799	27368891	E067	7095
chr21	27369037	27369100	E067	7333
chr21	27369145	27369226	E067	7441
chr21	27369256	27369324	E067	7552
chr21	27369514	27369591	E067	7810
chr21	27369611	27369709	E067	7907
chr21	27369924	27369984	E067	8220
chr21	27370068	27370108	E067	8364
chr21	27370152	27370329	E067	8448
chr21	27370351	27371100	E067	8647
chr21	27371163	27371296	E067	9459
chr21	27371716	27371783	E067	10012
chr21	27371903	27372053	E067	10199
chr21	27372094	27372774	E067	10390
chr21	27374885	27374935	E067	13181
chr21	27375617	27375704	E067	13913
chr21	27375896	27376209	E067	14192
chr21	27376294	27376367	E067	14590
chr21	27378156	27378206	E067	16452
chr21	27378528	27378840	E067	16824
chr21	27380968	27381038	E067	19264
chr21	27381187	27381408	E067	19483
chr21	27381600	27381702	E067	19896
chr21	27381909	27381959	E067	20205
chr21	27382288	27382343	E067	20584
chr21	27382414	27382471	E067	20710
chr21	27382582	27382893	E067	20878
chr21	27383715	27383870	E067	22011
chr21	27383896	27384025	E067	22192
chr21	27384215	27384286	E067	22511
chr21	27384299	27384473	E067	22595
chr21	27384703	27384757	E067	22999
chr21	27386207	27386293	E067	24503
chr21	27386307	27386536	E067	24603
chr21	27386857	27386982	E067	25153
chr21	27395958	27396099	E067	34254
chr21	27396305	27396392	E067	34601
chr21	27396649	27396728	E067	34945
chr21	27396813	27396883	E067	35109
chr21	27397115	27397207	E067	35411
chr21	27397573	27397623	E067	35869
chr21	27397629	27397705	E067	35925
chr21	27397894	27398078	E067	36190
chr21	27398217	27398295	E067	36513
chr21	27398318	27398456	E067	36614
chr21	27398624	27398808	E067	36920
chr21	27399187	27399237	E067	37483
chr21	27399394	27399438	E067	37690
chr21	27400645	27400748	E067	38941
chr21	27401187	27401297	E067	39483
chr21	27401603	27401714	E067	39899
chr21	27401851	27401891	E067	40147
chr21	27401972	27402032	E067	40268
chr21	27402304	27402386	E067	40600
chr21	27405522	27405582	E067	43818
chr21	27405605	27405670	E067	43901
chr21	27406205	27406411	E067	44501
chr21	27407048	27407144	E067	45344
chr21	27407150	27407265	E067	45446
chr21	27407356	27407436	E067	45652
chr21	27407482	27407539	E067	45778
chr21	27407573	27407721	E067	45869
chr21	27407763	27407836	E067	46059
chr21	27408012	27408137	E067	46308
chr21	27408206	27408464	E067	46502
chr21	27408622	27408746	E067	46918
chr21	27408861	27408941	E067	47157
chr21	27409270	27409592	E067	47566
chr21	27411439	27411645	E067	49735
chr21	27311778	27312050	E068	-49654
chr21	27314389	27314433	E068	-47271
chr21	27314555	27314842	E068	-46862
chr21	27314933	27315045	E068	-46659
chr21	27316403	27316466	E068	-45238
chr21	27316518	27316657	E068	-45047
chr21	27316739	27316815	E068	-44889
chr21	27317022	27317484	E068	-44220
chr21	27319728	27319778	E068	-41926
chr21	27326649	27327236	E068	-34468
chr21	27327933	27327995	E068	-33709
chr21	27328027	27328229	E068	-33475
chr21	27329154	27329217	E068	-32487
chr21	27329468	27329575	E068	-32129
chr21	27329673	27329985	E068	-31719
chr21	27330036	27330110	E068	-31594
chr21	27330204	27330261	E068	-31443
chr21	27330353	27330403	E068	-31301
chr21	27336051	27336114	E068	-25590
chr21	27336154	27336293	E068	-25411
chr21	27337961	27338059	E068	-23645
chr21	27338231	27338348	E068	-23356
chr21	27338422	27338500	E068	-23204
chr21	27339208	27339548	E068	-22156
chr21	27339845	27340417	E068	-21287
chr21	27352275	27352506	E068	-9198
chr21	27352684	27352856	E068	-8848
chr21	27352995	27353450	E068	-8254
chr21	27353763	27353823	E068	-7881
chr21	27354622	27354707	E068	-6997
chr21	27354726	27354770	E068	-6934
chr21	27354984	27355034	E068	-6670
chr21	27355653	27355779	E068	-5925
chr21	27355860	27355938	E068	-5766
chr21	27356031	27356504	E068	-5200
chr21	27356746	27356812	E068	-4892
chr21	27357052	27357154	E068	-4550
chr21	27357332	27357382	E068	-4322
chr21	27357636	27357808	E068	-3896
chr21	27358108	27358215	E068	-3489
chr21	27358757	27358816	E068	-2888
chr21	27359054	27359174	E068	-2530
chr21	27359239	27359289	E068	-2415
chr21	27359379	27359530	E068	-2174
chr21	27359532	27359576	E068	-2128
chr21	27359981	27360073	E068	-1631
chr21	27360115	27360169	E068	-1535
chr21	27360223	27360316	E068	-1388
chr21	27360343	27360391	E068	-1313
chr21	27360423	27360535	E068	-1169
chr21	27360546	27360614	E068	-1090
chr21	27366945	27367356	E068	5241
chr21	27367659	27368066	E068	5955
chr21	27368520	27368636	E068	6816
chr21	27368799	27368891	E068	7095
chr21	27369037	27369100	E068	7333
chr21	27369145	27369226	E068	7441
chr21	27369256	27369324	E068	7552
chr21	27369514	27369591	E068	7810
chr21	27369611	27369709	E068	7907
chr21	27369924	27369984	E068	8220
chr21	27370068	27370108	E068	8364
chr21	27370152	27370329	E068	8448
chr21	27370351	27371100	E068	8647
chr21	27371903	27372053	E068	10199
chr21	27372094	27372774	E068	10390
chr21	27373812	27373940	E068	12108
chr21	27374014	27374064	E068	12310
chr21	27374351	27374550	E068	12647
chr21	27374717	27374760	E068	13013
chr21	27374885	27374935	E068	13181
chr21	27375130	27375181	E068	13426
chr21	27375460	27375552	E068	13756
chr21	27375617	27375704	E068	13913
chr21	27378528	27378840	E068	16824
chr21	27381187	27381408	E068	19483
chr21	27381600	27381702	E068	19896
chr21	27381909	27381959	E068	20205
chr21	27382288	27382343	E068	20584
chr21	27382414	27382471	E068	20710
chr21	27383715	27383870	E068	22011
chr21	27383896	27384025	E068	22192
chr21	27391569	27391704	E068	29865
chr21	27391728	27391804	E068	30024
chr21	27391851	27391923	E068	30147
chr21	27398217	27398295	E068	36513
chr21	27399187	27399237	E068	37483
chr21	27399394	27399438	E068	37690
chr21	27399685	27399735	E068	37981
chr21	27400136	27400297	E068	38432
chr21	27400645	27400748	E068	38941
chr21	27401187	27401297	E068	39483
chr21	27405522	27405582	E068	43818
chr21	27405605	27405670	E068	43901
chr21	27406205	27406411	E068	44501
chr21	27407048	27407144	E068	45344
chr21	27407150	27407265	E068	45446
chr21	27407356	27407436	E068	45652
chr21	27407482	27407539	E068	45778
chr21	27407573	27407721	E068	45869
chr21	27407763	27407836	E068	46059
chr21	27408012	27408137	E068	46308
chr21	27408206	27408464	E068	46502
chr21	27408622	27408746	E068	46918
chr21	27408861	27408941	E068	47157
chr21	27411439	27411645	E068	49735
chr21	27311778	27312050	E069	-49654
chr21	27313240	27313307	E069	-48397
chr21	27314389	27314433	E069	-47271
chr21	27314555	27314842	E069	-46862
chr21	27314933	27315045	E069	-46659
chr21	27316073	27316142	E069	-45562
chr21	27316283	27316352	E069	-45352
chr21	27316403	27316466	E069	-45238
chr21	27316518	27316657	E069	-45047
chr21	27316739	27316815	E069	-44889
chr21	27317022	27317484	E069	-44220
chr21	27323253	27323353	E069	-38351
chr21	27333351	27333796	E069	-27908
chr21	27335528	27335915	E069	-25789
chr21	27336051	27336114	E069	-25590
chr21	27336154	27336293	E069	-25411
chr21	27336429	27336621	E069	-25083
chr21	27336786	27336826	E069	-24878
chr21	27339208	27339548	E069	-22156
chr21	27339845	27340417	E069	-21287
chr21	27340482	27340608	E069	-21096
chr21	27340799	27340849	E069	-20855
chr21	27340942	27341022	E069	-20682
chr21	27341718	27341768	E069	-19936
chr21	27341840	27341903	E069	-19801
chr21	27341904	27341987	E069	-19717
chr21	27343215	27343259	E069	-18445
chr21	27343742	27343792	E069	-17912
chr21	27352275	27352506	E069	-9198
chr21	27352684	27352856	E069	-8848
chr21	27352995	27353450	E069	-8254
chr21	27353763	27353823	E069	-7881
chr21	27354984	27355034	E069	-6670
chr21	27355653	27355779	E069	-5925
chr21	27355860	27355938	E069	-5766
chr21	27356031	27356504	E069	-5200
chr21	27356746	27356812	E069	-4892
chr21	27357052	27357154	E069	-4550
chr21	27357332	27357382	E069	-4322
chr21	27357636	27357808	E069	-3896
chr21	27358108	27358215	E069	-3489
chr21	27358470	27358544	E069	-3160
chr21	27358757	27358816	E069	-2888
chr21	27359054	27359174	E069	-2530
chr21	27359981	27360073	E069	-1631
chr21	27360115	27360169	E069	-1535
chr21	27360223	27360316	E069	-1388
chr21	27360343	27360391	E069	-1313
chr21	27360423	27360535	E069	-1169
chr21	27360546	27360614	E069	-1090
chr21	27360638	27360757	E069	-947
chr21	27361497	27361586	E069	-118
chr21	27363246	27363296	E069	1542
chr21	27365882	27366131	E069	4178
chr21	27366286	27366393	E069	4582
chr21	27366557	27366611	E069	4853
chr21	27366751	27366834	E069	5047
chr21	27366945	27367356	E069	5241
chr21	27367659	27368066	E069	5955
chr21	27368520	27368636	E069	6816
chr21	27368799	27368891	E069	7095
chr21	27369037	27369100	E069	7333
chr21	27369145	27369226	E069	7441
chr21	27369256	27369324	E069	7552
chr21	27369514	27369591	E069	7810
chr21	27369611	27369709	E069	7907
chr21	27369924	27369984	E069	8220
chr21	27370068	27370108	E069	8364
chr21	27370152	27370329	E069	8448
chr21	27370351	27371100	E069	8647
chr21	27371716	27371783	E069	10012
chr21	27371903	27372053	E069	10199
chr21	27372094	27372774	E069	10390
chr21	27374351	27374550	E069	12647
chr21	27374717	27374760	E069	13013
chr21	27374885	27374935	E069	13181
chr21	27375130	27375181	E069	13426
chr21	27375460	27375552	E069	13756
chr21	27375617	27375704	E069	13913
chr21	27375896	27376209	E069	14192
chr21	27376294	27376367	E069	14590
chr21	27380968	27381038	E069	19264
chr21	27381187	27381408	E069	19483
chr21	27382414	27382471	E069	20710
chr21	27382582	27382893	E069	20878
chr21	27383715	27383870	E069	22011
chr21	27383896	27384025	E069	22192
chr21	27384215	27384286	E069	22511
chr21	27384299	27384473	E069	22595
chr21	27384703	27384757	E069	22999
chr21	27391569	27391704	E069	29865
chr21	27391728	27391804	E069	30024
chr21	27391851	27391923	E069	30147
chr21	27392133	27392206	E069	30429
chr21	27396305	27396392	E069	34601
chr21	27396649	27396728	E069	34945
chr21	27397573	27397623	E069	35869
chr21	27397629	27397705	E069	35925
chr21	27397894	27398078	E069	36190
chr21	27398217	27398295	E069	36513
chr21	27398318	27398456	E069	36614
chr21	27398624	27398808	E069	36920
chr21	27399187	27399237	E069	37483
chr21	27399394	27399438	E069	37690
chr21	27399685	27399735	E069	37981
chr21	27400136	27400297	E069	38432
chr21	27400645	27400748	E069	38941
chr21	27401187	27401297	E069	39483
chr21	27405522	27405582	E069	43818
chr21	27405605	27405670	E069	43901
chr21	27406205	27406411	E069	44501
chr21	27407048	27407144	E069	45344
chr21	27407150	27407265	E069	45446
chr21	27407356	27407436	E069	45652
chr21	27407482	27407539	E069	45778
chr21	27407573	27407721	E069	45869
chr21	27407763	27407836	E069	46059
chr21	27408012	27408137	E069	46308
chr21	27408206	27408464	E069	46502
chr21	27408622	27408746	E069	46918
chr21	27408861	27408941	E069	47157
chr21	27409270	27409592	E069	47566
chr21	27411439	27411645	E069	49735
chr21	27311778	27312050	E070	-49654
chr21	27359054	27359174	E070	-2530
chr21	27359239	27359289	E070	-2415
chr21	27359379	27359530	E070	-2174
chr21	27359532	27359576	E070	-2128
chr21	27366945	27367356	E070	5241
chr21	27367659	27368066	E070	5955
chr21	27370068	27370108	E070	8364
chr21	27370152	27370329	E070	8448
chr21	27375130	27375181	E070	13426
chr21	27375460	27375552	E070	13756
chr21	27376294	27376367	E070	14590
chr21	27378528	27378840	E070	16824
chr21	27380610	27380881	E070	18906
chr21	27397894	27398078	E070	36190
chr21	27398217	27398295	E070	36513
chr21	27406205	27406411	E070	44501
chr21	27311778	27312050	E071	-49654
chr21	27314389	27314433	E071	-47271
chr21	27314555	27314842	E071	-46862
chr21	27314933	27315045	E071	-46659
chr21	27316283	27316352	E071	-45352
chr21	27316403	27316466	E071	-45238
chr21	27316518	27316657	E071	-45047
chr21	27316739	27316815	E071	-44889
chr21	27317022	27317484	E071	-44220
chr21	27320795	27321208	E071	-40496
chr21	27326003	27326394	E071	-35310
chr21	27326649	27327236	E071	-34468
chr21	27329154	27329217	E071	-32487
chr21	27329468	27329575	E071	-32129
chr21	27329673	27329985	E071	-31719
chr21	27332749	27333279	E071	-28425
chr21	27333351	27333796	E071	-27908
chr21	27339208	27339548	E071	-22156
chr21	27339845	27340417	E071	-21287
chr21	27340482	27340608	E071	-21096
chr21	27340799	27340849	E071	-20855
chr21	27340942	27341022	E071	-20682
chr21	27341718	27341768	E071	-19936
chr21	27341840	27341903	E071	-19801
chr21	27341904	27341987	E071	-19717
chr21	27343742	27343792	E071	-17912
chr21	27344084	27344144	E071	-17560
chr21	27352275	27352506	E071	-9198
chr21	27352684	27352856	E071	-8848
chr21	27352995	27353450	E071	-8254
chr21	27353763	27353823	E071	-7881
chr21	27354622	27354707	E071	-6997
chr21	27354726	27354770	E071	-6934
chr21	27354984	27355034	E071	-6670
chr21	27355653	27355779	E071	-5925
chr21	27355860	27355938	E071	-5766
chr21	27356031	27356504	E071	-5200
chr21	27359239	27359289	E071	-2415
chr21	27359379	27359530	E071	-2174
chr21	27359532	27359576	E071	-2128
chr21	27363643	27363693	E071	1939
chr21	27365882	27366131	E071	4178
chr21	27366286	27366393	E071	4582
chr21	27366557	27366611	E071	4853
chr21	27366751	27366834	E071	5047
chr21	27366945	27367356	E071	5241
chr21	27367659	27368066	E071	5955
chr21	27368520	27368636	E071	6816
chr21	27368799	27368891	E071	7095
chr21	27369037	27369100	E071	7333
chr21	27369145	27369226	E071	7441
chr21	27369256	27369324	E071	7552
chr21	27369514	27369591	E071	7810
chr21	27369611	27369709	E071	7907
chr21	27369924	27369984	E071	8220
chr21	27370068	27370108	E071	8364
chr21	27370152	27370329	E071	8448
chr21	27370351	27371100	E071	8647
chr21	27371163	27371296	E071	9459
chr21	27371716	27371783	E071	10012
chr21	27371903	27372053	E071	10199
chr21	27372094	27372774	E071	10390
chr21	27374351	27374550	E071	12647
chr21	27374717	27374760	E071	13013
chr21	27374885	27374935	E071	13181
chr21	27375130	27375181	E071	13426
chr21	27375460	27375552	E071	13756
chr21	27375617	27375704	E071	13913
chr21	27378156	27378206	E071	16452
chr21	27379874	27379918	E071	18170
chr21	27380038	27380164	E071	18334
chr21	27380968	27381038	E071	19264
chr21	27381187	27381408	E071	19483
chr21	27383715	27383870	E071	22011
chr21	27383896	27384025	E071	22192
chr21	27386207	27386293	E071	24503
chr21	27386307	27386536	E071	24603
chr21	27386857	27386982	E071	25153
chr21	27391569	27391704	E071	29865
chr21	27391728	27391804	E071	30024
chr21	27391851	27391923	E071	30147
chr21	27395817	27395898	E071	34113
chr21	27395958	27396099	E071	34254
chr21	27396305	27396392	E071	34601
chr21	27396649	27396728	E071	34945
chr21	27396813	27396883	E071	35109
chr21	27397629	27397705	E071	35925
chr21	27397894	27398078	E071	36190
chr21	27398217	27398295	E071	36513
chr21	27398318	27398456	E071	36614
chr21	27398624	27398808	E071	36920
chr21	27399187	27399237	E071	37483
chr21	27399394	27399438	E071	37690
chr21	27399685	27399735	E071	37981
chr21	27400136	27400297	E071	38432
chr21	27400645	27400748	E071	38941
chr21	27401187	27401297	E071	39483
chr21	27405522	27405582	E071	43818
chr21	27405605	27405670	E071	43901
chr21	27406205	27406411	E071	44501
chr21	27407048	27407144	E071	45344
chr21	27407150	27407265	E071	45446
chr21	27407356	27407436	E071	45652
chr21	27407482	27407539	E071	45778
chr21	27407573	27407721	E071	45869
chr21	27407763	27407836	E071	46059
chr21	27408012	27408137	E071	46308
chr21	27408206	27408464	E071	46502
chr21	27408622	27408746	E071	46918
chr21	27408861	27408941	E071	47157
chr21	27411439	27411645	E071	49735
chr21	27311778	27312050	E072	-49654
chr21	27314389	27314433	E072	-47271
chr21	27314555	27314842	E072	-46862
chr21	27314933	27315045	E072	-46659
chr21	27316518	27316657	E072	-45047
chr21	27316739	27316815	E072	-44889
chr21	27317022	27317484	E072	-44220
chr21	27326003	27326394	E072	-35310
chr21	27332749	27333279	E072	-28425
chr21	27333351	27333796	E072	-27908
chr21	27339845	27340417	E072	-21287
chr21	27340482	27340608	E072	-21096
chr21	27340799	27340849	E072	-20855
chr21	27340942	27341022	E072	-20682
chr21	27341718	27341768	E072	-19936
chr21	27343742	27343792	E072	-17912
chr21	27352275	27352506	E072	-9198
chr21	27352684	27352856	E072	-8848
chr21	27352995	27353450	E072	-8254
chr21	27353763	27353823	E072	-7881
chr21	27354622	27354707	E072	-6997
chr21	27354726	27354770	E072	-6934
chr21	27354984	27355034	E072	-6670
chr21	27355653	27355779	E072	-5925
chr21	27355860	27355938	E072	-5766
chr21	27356031	27356504	E072	-5200
chr21	27356746	27356812	E072	-4892
chr21	27357052	27357154	E072	-4550
chr21	27357332	27357382	E072	-4322
chr21	27357636	27357808	E072	-3896
chr21	27358108	27358215	E072	-3489
chr21	27358470	27358544	E072	-3160
chr21	27358757	27358816	E072	-2888
chr21	27359054	27359174	E072	-2530
chr21	27359981	27360073	E072	-1631
chr21	27360115	27360169	E072	-1535
chr21	27365882	27366131	E072	4178
chr21	27366286	27366393	E072	4582
chr21	27366557	27366611	E072	4853
chr21	27366751	27366834	E072	5047
chr21	27366945	27367356	E072	5241
chr21	27367659	27368066	E072	5955
chr21	27368520	27368636	E072	6816
chr21	27368799	27368891	E072	7095
chr21	27369037	27369100	E072	7333
chr21	27369145	27369226	E072	7441
chr21	27369256	27369324	E072	7552
chr21	27369514	27369591	E072	7810
chr21	27369611	27369709	E072	7907
chr21	27369924	27369984	E072	8220
chr21	27370068	27370108	E072	8364
chr21	27370152	27370329	E072	8448
chr21	27370351	27371100	E072	8647
chr21	27371163	27371296	E072	9459
chr21	27371716	27371783	E072	10012
chr21	27371903	27372053	E072	10199
chr21	27372094	27372774	E072	10390
chr21	27374014	27374064	E072	12310
chr21	27374351	27374550	E072	12647
chr21	27374717	27374760	E072	13013
chr21	27374885	27374935	E072	13181
chr21	27375130	27375181	E072	13426
chr21	27375460	27375552	E072	13756
chr21	27375617	27375704	E072	13913
chr21	27375896	27376209	E072	14192
chr21	27376294	27376367	E072	14590
chr21	27378528	27378840	E072	16824
chr21	27379874	27379918	E072	18170
chr21	27380038	27380164	E072	18334
chr21	27380968	27381038	E072	19264
chr21	27381187	27381408	E072	19483
chr21	27381600	27381702	E072	19896
chr21	27381909	27381959	E072	20205
chr21	27382288	27382343	E072	20584
chr21	27382414	27382471	E072	20710
chr21	27383715	27383870	E072	22011
chr21	27383896	27384025	E072	22192
chr21	27384215	27384286	E072	22511
chr21	27384299	27384473	E072	22595
chr21	27391569	27391704	E072	29865
chr21	27391728	27391804	E072	30024
chr21	27391851	27391923	E072	30147
chr21	27392133	27392206	E072	30429
chr21	27395817	27395898	E072	34113
chr21	27395958	27396099	E072	34254
chr21	27397573	27397623	E072	35869
chr21	27397629	27397705	E072	35925
chr21	27397894	27398078	E072	36190
chr21	27398217	27398295	E072	36513
chr21	27398318	27398456	E072	36614
chr21	27398624	27398808	E072	36920
chr21	27399187	27399237	E072	37483
chr21	27399394	27399438	E072	37690
chr21	27399685	27399735	E072	37981
chr21	27400136	27400297	E072	38432
chr21	27400645	27400748	E072	38941
chr21	27401187	27401297	E072	39483
chr21	27401603	27401714	E072	39899
chr21	27401851	27401891	E072	40147
chr21	27401972	27402032	E072	40268
chr21	27406205	27406411	E072	44501
chr21	27407048	27407144	E072	45344
chr21	27407150	27407265	E072	45446
chr21	27407356	27407436	E072	45652
chr21	27407482	27407539	E072	45778
chr21	27407573	27407721	E072	45869
chr21	27407763	27407836	E072	46059
chr21	27408012	27408137	E072	46308
chr21	27408206	27408464	E072	46502
chr21	27411439	27411645	E072	49735
chr21	27314389	27314433	E073	-47271
chr21	27314555	27314842	E073	-46862
chr21	27314933	27315045	E073	-46659
chr21	27316403	27316466	E073	-45238
chr21	27316518	27316657	E073	-45047
chr21	27316739	27316815	E073	-44889
chr21	27343215	27343259	E073	-18445
chr21	27348154	27348243	E073	-13461
chr21	27349101	27349151	E073	-12553
chr21	27349304	27349423	E073	-12281
chr21	27349642	27349698	E073	-12006
chr21	27352684	27352856	E073	-8848
chr21	27352995	27353450	E073	-8254
chr21	27354622	27354707	E073	-6997
chr21	27354726	27354770	E073	-6934
chr21	27354984	27355034	E073	-6670
chr21	27357052	27357154	E073	-4550
chr21	27357332	27357382	E073	-4322
chr21	27357636	27357808	E073	-3896
chr21	27358470	27358544	E073	-3160
chr21	27366945	27367356	E073	5241
chr21	27367659	27368066	E073	5955
chr21	27368520	27368636	E073	6816
chr21	27368799	27368891	E073	7095
chr21	27369924	27369984	E073	8220
chr21	27370068	27370108	E073	8364
chr21	27370152	27370329	E073	8448
chr21	27370351	27371100	E073	8647
chr21	27374351	27374550	E073	12647
chr21	27374717	27374760	E073	13013
chr21	27374885	27374935	E073	13181
chr21	27375130	27375181	E073	13426
chr21	27375460	27375552	E073	13756
chr21	27375617	27375704	E073	13913
chr21	27375896	27376209	E073	14192
chr21	27376294	27376367	E073	14590
chr21	27380968	27381038	E073	19264
chr21	27383715	27383870	E073	22011
chr21	27383896	27384025	E073	22192
chr21	27384215	27384286	E073	22511
chr21	27384299	27384473	E073	22595
chr21	27384703	27384757	E073	22999
chr21	27391569	27391704	E073	29865
chr21	27391728	27391804	E073	30024
chr21	27391851	27391923	E073	30147
chr21	27392133	27392206	E073	30429
chr21	27397894	27398078	E073	36190
chr21	27398217	27398295	E073	36513
chr21	27398318	27398456	E073	36614
chr21	27399685	27399735	E073	37981
chr21	27400136	27400297	E073	38432
chr21	27400645	27400748	E073	38941
chr21	27401187	27401297	E073	39483
chr21	27406205	27406411	E073	44501
chr21	27407048	27407144	E073	45344
chr21	27407150	27407265	E073	45446
chr21	27407356	27407436	E073	45652
chr21	27407482	27407539	E073	45778
chr21	27407573	27407721	E073	45869
chr21	27407763	27407836	E073	46059
chr21	27408012	27408137	E073	46308
chr21	27408206	27408464	E073	46502
chr21	27408622	27408746	E073	46918
chr21	27408861	27408941	E073	47157
chr21	27311778	27312050	E074	-49654
chr21	27314389	27314433	E074	-47271
chr21	27314555	27314842	E074	-46862
chr21	27314933	27315045	E074	-46659
chr21	27316518	27316657	E074	-45047
chr21	27316739	27316815	E074	-44889
chr21	27317022	27317484	E074	-44220
chr21	27320795	27321208	E074	-40496
chr21	27321375	27321459	E074	-40245
chr21	27321554	27321613	E074	-40091
chr21	27322026	27322757	E074	-38947
chr21	27324299	27324349	E074	-37355
chr21	27326003	27326394	E074	-35310
chr21	27329154	27329217	E074	-32487
chr21	27329468	27329575	E074	-32129
chr21	27329673	27329985	E074	-31719
chr21	27330036	27330110	E074	-31594
chr21	27332749	27333279	E074	-28425
chr21	27335528	27335915	E074	-25789
chr21	27339845	27340417	E074	-21287
chr21	27340482	27340608	E074	-21096
chr21	27340799	27340849	E074	-20855
chr21	27340942	27341022	E074	-20682
chr21	27341718	27341768	E074	-19936
chr21	27341840	27341903	E074	-19801
chr21	27341904	27341987	E074	-19717
chr21	27343742	27343792	E074	-17912
chr21	27344084	27344144	E074	-17560
chr21	27352995	27353450	E074	-8254
chr21	27353763	27353823	E074	-7881
chr21	27354622	27354707	E074	-6997
chr21	27354726	27354770	E074	-6934
chr21	27354984	27355034	E074	-6670
chr21	27355653	27355779	E074	-5925
chr21	27355860	27355938	E074	-5766
chr21	27356031	27356504	E074	-5200
chr21	27357332	27357382	E074	-4322
chr21	27357636	27357808	E074	-3896
chr21	27358108	27358215	E074	-3489
chr21	27358470	27358544	E074	-3160
chr21	27358757	27358816	E074	-2888
chr21	27359054	27359174	E074	-2530
chr21	27359239	27359289	E074	-2415
chr21	27359379	27359530	E074	-2174
chr21	27359532	27359576	E074	-2128
chr21	27359981	27360073	E074	-1631
chr21	27360115	27360169	E074	-1535
chr21	27360223	27360316	E074	-1388
chr21	27360343	27360391	E074	-1313
chr21	27360423	27360535	E074	-1169
chr21	27360546	27360614	E074	-1090
chr21	27363246	27363296	E074	1542
chr21	27363643	27363693	E074	1939
chr21	27365882	27366131	E074	4178
chr21	27366286	27366393	E074	4582
chr21	27366557	27366611	E074	4853
chr21	27366751	27366834	E074	5047
chr21	27366945	27367356	E074	5241
chr21	27367659	27368066	E074	5955
chr21	27368520	27368636	E074	6816
chr21	27368799	27368891	E074	7095
chr21	27369037	27369100	E074	7333
chr21	27369145	27369226	E074	7441
chr21	27369256	27369324	E074	7552
chr21	27369514	27369591	E074	7810
chr21	27369611	27369709	E074	7907
chr21	27369924	27369984	E074	8220
chr21	27370068	27370108	E074	8364
chr21	27370152	27370329	E074	8448
chr21	27370351	27371100	E074	8647
chr21	27371163	27371296	E074	9459
chr21	27371716	27371783	E074	10012
chr21	27371903	27372053	E074	10199
chr21	27372094	27372774	E074	10390
chr21	27373812	27373940	E074	12108
chr21	27374014	27374064	E074	12310
chr21	27374351	27374550	E074	12647
chr21	27374717	27374760	E074	13013
chr21	27374885	27374935	E074	13181
chr21	27375130	27375181	E074	13426
chr21	27375460	27375552	E074	13756
chr21	27375617	27375704	E074	13913
chr21	27375896	27376209	E074	14192
chr21	27378156	27378206	E074	16452
chr21	27378528	27378840	E074	16824
chr21	27379874	27379918	E074	18170
chr21	27380038	27380164	E074	18334
chr21	27380259	27380601	E074	18555
chr21	27383715	27383870	E074	22011
chr21	27383896	27384025	E074	22192
chr21	27384215	27384286	E074	22511
chr21	27384299	27384473	E074	22595
chr21	27391569	27391704	E074	29865
chr21	27391728	27391804	E074	30024
chr21	27391851	27391923	E074	30147
chr21	27396813	27396883	E074	35109
chr21	27397115	27397207	E074	35411
chr21	27397573	27397623	E074	35869
chr21	27397629	27397705	E074	35925
chr21	27397894	27398078	E074	36190
chr21	27398217	27398295	E074	36513
chr21	27398318	27398456	E074	36614
chr21	27398624	27398808	E074	36920
chr21	27399187	27399237	E074	37483
chr21	27399394	27399438	E074	37690
chr21	27399685	27399735	E074	37981
chr21	27400136	27400297	E074	38432
chr21	27400645	27400748	E074	38941
chr21	27401187	27401297	E074	39483
chr21	27405522	27405582	E074	43818
chr21	27405605	27405670	E074	43901
chr21	27406205	27406411	E074	44501
chr21	27407356	27407436	E074	45652
chr21	27407482	27407539	E074	45778
chr21	27407573	27407721	E074	45869
chr21	27407763	27407836	E074	46059
chr21	27408012	27408137	E074	46308
chr21	27408206	27408464	E074	46502
chr21	27408622	27408746	E074	46918
chr21	27408861	27408941	E074	47157
chr21	27409270	27409592	E074	47566
chr21	27411439	27411645	E074	49735
chr21	27311778	27312050	E081	-49654
chr21	27329154	27329217	E081	-32487
chr21	27365882	27366131	E081	4178
chr21	27366286	27366393	E081	4582
chr21	27366557	27366611	E081	4853
chr21	27366751	27366834	E081	5047
chr21	27366945	27367356	E081	5241
chr21	27367659	27368066	E081	5955
chr21	27368520	27368636	E081	6816
chr21	27368799	27368891	E081	7095
chr21	27369037	27369100	E081	7333
chr21	27369145	27369226	E081	7441
chr21	27369256	27369324	E081	7552
chr21	27369514	27369591	E081	7810
chr21	27369611	27369709	E081	7907
chr21	27369924	27369984	E081	8220
chr21	27370068	27370108	E081	8364
chr21	27370152	27370329	E081	8448
chr21	27370351	27371100	E081	8647
chr21	27380259	27380601	E081	18555
chr21	27380610	27380881	E081	18906
chr21	27380968	27381038	E081	19264
chr21	27381187	27381408	E081	19483
chr21	27383715	27383870	E081	22011
chr21	27383896	27384025	E081	22192
chr21	27384215	27384286	E081	22511
chr21	27384299	27384473	E081	22595
chr21	27406205	27406411	E081	44501
chr21	27408861	27408941	E081	47157
chr21	27409270	27409592	E081	47566
chr21	27409642	27409692	E081	47938
chr21	27311778	27312050	E082	-49654
chr21	27359239	27359289	E082	-2415
chr21	27359379	27359530	E082	-2174
chr21	27359532	27359576	E082	-2128
chr21	27366286	27366393	E082	4582
chr21	27366557	27366611	E082	4853
chr21	27366751	27366834	E082	5047
chr21	27366945	27367356	E082	5241
chr21	27367659	27368066	E082	5955
chr21	27368520	27368636	E082	6816
chr21	27368799	27368891	E082	7095
chr21	27369037	27369100	E082	7333
chr21	27380259	27380601	E082	18555
chr21	27380610	27380881	E082	18906
chr21	27380968	27381038	E082	19264
chr21	27381187	27381408	E082	19483
chr21	27382414	27382471	E082	20710
chr21	27382582	27382893	E082	20878
chr21	27398624	27398808	E082	36920
chr21	27406205	27406411	E082	44501

Promoter Annotation (GRCh37.p13)

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr21	27342490	27342791	E067	-18913
chr21	27342804	27342914	E067	-18790
chr21	27342948	27343173	E067	-18531
chr21	27342490	27342791	E068	-18913
chr21	27342804	27342914	E068	-18790
chr21	27342948	27343173	E068	-18531
chr21	27342490	27342791	E069	-18913
chr21	27342804	27342914	E069	-18790
chr21	27342948	27343173	E069	-18531
chr21	27342490	27342791	E071	-18913
chr21	27342804	27342914	E071	-18790
chr21	27342948	27343173	E071	-18531
chr21	27342490	27342791	E072	-18913
chr21	27342804	27342914	E072	-18790
chr21	27342948	27343173	E072	-18531
chr21	27342490	27342791	E073	-18913
chr21	27342804	27342914	E073	-18790
chr21	27342948	27343173	E073	-18531
chr21	27342490	27342791	E074	-18913
chr21	27342804	27342914	E074	-18790
chr21	27342948	27343173	E074	-18531