SNP Detail Info-rs728115

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

KCND2 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0148 (4448/29888,GnomAD)
A=0179 (895/5008,1000G)
A=0103 (397/3854,ALSPAC)
A=0092 (342/3708,TWINSUK)

Position: chr7:120665095 (GRCh38.p7) (7q31.31)

Phenotype: ND

Dataset:

GWASdb2 | GWASCatalog

Publications: 2 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Molecule type	Change	Amino acid[Codon]	SO Term
KCND2 transcript	NM_012281.2:c.	N/A	Intron Variant
KCND2 transcript variant X1	XM_011516165.2:c.	N/A	Genic Downstream Transcript Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.906	A=0.094
1000Genomes	American	Sub	694	G=0.770	A=0.230
1000Genomes	East Asian	Sub	1008	G=0.586	A=0.414
1000Genomes	Europe	Sub	1006	G=0.896	A=0.104
1000Genomes	Global	Study-wide	5008	G=0.821	A=0.179
1000Genomes	South Asian	Sub	978	G=0.910	A=0.090
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.897	A=0.103
The Genome Aggregation Database	African	Sub	8714	G=0.887	A=0.113
The Genome Aggregation Database	American	Sub	838	G=0.740	A=0.260
The Genome Aggregation Database	East Asian	Sub	1612	G=0.584	A=0.416
The Genome Aggregation Database	Europe	Sub	18422	G=0.862	A=0.137
The Genome Aggregation Database	Global	Study-wide	29888	G=0.851	A=0.148
The Genome Aggregation Database	Other	Sub	302	G=0.850	A=0.150
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.908	A=0.092

PMID	Title	Author	Journal
21956439	Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.	Zuo L	Neuropsychopharmacology
22488850	Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence.	Zuo L	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs728115	4E-06	alcohol and nictotine co-dependence	22488850

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs728115