rs7293345

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0434 (12855/29614,GnomAD)
C==0459 (2301/5008,1000G)
C==0367 (1415/3854,ALSPAC)
C==0367 (1362/3708,TWINSUK)
chr5:46332281 (GRCh38.p7) (5p11)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.46332281C>T
GRCh37.p13 chr 5NC_000005.9:g.46332383C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.685T=0.315
1000GenomesAmericanSub694C=0.340T=0.660
1000GenomesEast AsianSub1008C=0.469T=0.531
1000GenomesEuropeSub1006C=0.334T=0.666
1000GenomesGlobalStudy-wide5008C=0.459T=0.541
1000GenomesSouth AsianSub978C=0.360T=0.640
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.367T=0.633
The Genome Aggregation DatabaseAfricanSub8618C=0.658T=0.342
The Genome Aggregation DatabaseAmericanSub828C=0.340T=0.660
The Genome Aggregation DatabaseEast AsianSub1514C=0.513T=0.487
The Genome Aggregation DatabaseEuropeSub18354C=0.328T=0.671
The Genome Aggregation DatabaseGlobalStudy-wide29614C=0.434T=0.565
The Genome Aggregation DatabaseOtherSub300C=0.320T=0.680
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.367T=0.633
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs72933450.000639alcohol dependence20201924

eQTL of rs7293345 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7293345 in Fetal Brain

Probe ID Position Gene beta p-value
cg15950743chr5:49708521EMB-0.08361486099673163.2068e-29

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.