| Sequence Name | Change(s) |
|---|---|
| GRCh38.p7 chr 12 | NC_000012.12:g.8986686G>A |
| GRCh37.p13 chr 12 | NC_000012.11:g.9139282G>A |
| Study | Population | Group | Sample # | Ref Allele | Alt Allele |
|---|---|---|---|---|---|
| 1000Genomes | African | Sub | 1322 | G=0.700 | A=0.300 |
| 1000Genomes | American | Sub | 694 | G=0.580 | A=0.420 |
| 1000Genomes | East Asian | Sub | 1008 | G=0.937 | A=0.063 |
| 1000Genomes | Europe | Sub | 1006 | G=0.663 | A=0.337 |
| 1000Genomes | Global | Study-wide | 5008 | G=0.733 | A=0.267 |
| 1000Genomes | South Asian | Sub | 978 | G=0.750 | A=0.250 |
| The Avon Longitudinal Study of Parents and Children | PARENT AND CHILD COHORT | Study-wide | 3854 | G=0.655 | A=0.345 |
| The Genome Aggregation Database | African | Sub | 8678 | G=0.688 | A=0.312 |
| The Genome Aggregation Database | American | Sub | 832 | G=0.620 | A=0.380 |
| The Genome Aggregation Database | East Asian | Sub | 1610 | G=0.944 | A=0.056 |
| The Genome Aggregation Database | Europe | Sub | 18354 | G=0.629 | A=0.370 |
| The Genome Aggregation Database | Global | Study-wide | 29776 | G=0.664 | A=0.335 |
| The Genome Aggregation Database | Other | Sub | 302 | G=0.710 | A=0.290 |
| Trans-Omics for Precision Medicine | Global | Study-wide | 29118 | G=0.661 | A=0.338 |
| UK 10K study - Twins | TWIN COHORT | Study-wide | 3708 | G=0.651 | A=0.349 |
| PMID | Title | Author | Journal |
|---|---|---|---|
| 24277619 | ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample. | Quillen EE | Am J Med Genet B Neuropsychiatr Genet |
| SNP ID | p-value | Traits | Study |
|---|---|---|---|
| rs7296295 | 0.000224 | alcohol dependence | 24277619 |
| Position (v37) | eGene | GeneID | Variant | p-value | TSS | Tissue |
|---|---|---|---|---|---|---|
| Chr12:9139282 | KLRG1 | ENSG00000139187.5 | G>A | 1.5793e-8 | 36642 | Caudate_basal_ganglia |
| Probe ID | Position | Gene | beta | p-value | |||
|---|---|---|---|---|---|---|---|
| There is no meQTL annotation for this SNP | |||||||
There is no significant Hi-C chromatin interaction data for this SNP.
| Chromosome | Start | End | Region | Distance ( -/+ : Up/Downstream ) |
|---|---|---|---|---|
| chr12 | 9100408 | 9100609 | E067 | -38673 |
| chr12 | 9100066 | 9100112 | E068 | -39170 |
| chr12 | 9100189 | 9100331 | E068 | -38951 |
| chr12 | 9100408 | 9100609 | E068 | -38673 |
| chr12 | 9099714 | 9099764 | E069 | -39518 |
| chr12 | 9100066 | 9100112 | E069 | -39170 |
| chr12 | 9100189 | 9100331 | E069 | -38951 |
| chr12 | 9100408 | 9100609 | E069 | -38673 |
| chr12 | 9100189 | 9100331 | E070 | -38951 |
| chr12 | 9100408 | 9100609 | E070 | -38673 |
| chr12 | 9100408 | 9100609 | E071 | -38673 |
| chr12 | 9100189 | 9100331 | E072 | -38951 |
| chr12 | 9100408 | 9100609 | E072 | -38673 |
| chr12 | 9100189 | 9100331 | E073 | -38951 |
| chr12 | 9100408 | 9100609 | E073 | -38673 |
| chr12 | 9100066 | 9100112 | E074 | -39170 |
| chr12 | 9100189 | 9100331 | E074 | -38951 |
| chr12 | 9100408 | 9100609 | E074 | -38673 |
| chr12 | 9100189 | 9100331 | E082 | -38951 |
| chr12 | 9100408 | 9100609 | E082 | -38673 |
| Chromosome | Start | End | Region | Distance(-/+:Up/Downstream) |
|---|---|---|---|---|
| chr12 | 9101039 | 9104134 | E067 | -35148 |
| chr12 | 9101039 | 9104134 | E068 | -35148 |
| chr12 | 9101039 | 9104134 | E069 | -35148 |
| chr12 | 9101039 | 9104134 | E070 | -35148 |
| chr12 | 9101039 | 9104134 | E071 | -35148 |
| chr12 | 9101039 | 9104134 | E072 | -35148 |
| chr12 | 9101039 | 9104134 | E073 | -35148 |
| chr12 | 9101039 | 9104134 | E074 | -35148 |
| chr12 | 9101039 | 9104134 | E082 | -35148 |