rs73012959

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0032 (986/29970,GnomAD)
T=0027 (812/29118,TOPMED)
T=0054 (270/5008,1000G)
T=0040 (154/3854,ALSPAC)
T=0038 (140/3708,TWINSUK)
chr11:116618927 (GRCh38.p7) (11q23.3)
AD
GWASCatalog
1   publication(s)
See rs on genome
66 Enhancers around
4 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.116618927C>T
GRCh37.p13 chr 11NC_000011.9:g.116489644C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.996T=0.004
1000GenomesAmericanSub694C=0.970T=0.030
1000GenomesEast AsianSub1008C=0.864T=0.136
1000GenomesEuropeSub1006C=0.967T=0.033
1000GenomesGlobalStudy-wide5008C=0.946T=0.054
1000GenomesSouth AsianSub978C=0.920T=0.080
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.960T=0.040
The Genome Aggregation DatabaseAfricanSub8726C=0.993T=0.007
The Genome Aggregation DatabaseAmericanSub838C=0.970T=0.030
The Genome Aggregation DatabaseEast AsianSub1618C=0.825T=0.175
The Genome Aggregation DatabaseEuropeSub18486C=0.967T=0.032
The Genome Aggregation DatabaseGlobalStudy-wide29970C=0.967T=0.032
The Genome Aggregation DatabaseOtherSub302C=0.960T=0.040
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.972T=0.027
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.962T=0.038
PMID Title Author Journal
29460428Genomewide Association Study of Alcohol Dependence and Related Traits in a Thai Population.Gelernter JAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs730129596E-07alcohol dependence29460428

eQTL of rs73012959 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs73012959 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11116449394116449451E068-40193
chr11116472337116472458E068-17186
chr11116472556116472712E068-16932
chr11116472846116473125E068-16519
chr11116473322116473508E068-16136
chr11116440125116440201E070-49443
chr11116447334116447527E070-42117
chr11116447846116447900E070-41744
chr11116447997116448107E070-41537
chr11116448375116448464E070-41180
chr11116448519116448940E070-40704
chr11116449035116449085E070-40559
chr11116449394116449451E070-40193
chr11116452790116452979E070-36665
chr11116453026116453188E070-36456
chr11116453368116453574E070-36070
chr11116453703116453753E070-35891
chr11116453815116453865E070-35779
chr11116454019116454079E070-35565
chr11116466743116466793E070-22851
chr11116472846116473125E070-16519
chr11116473322116473508E070-16136
chr11116484508116484558E070-5086
chr11116484695116484740E070-4904
chr11116506703116506763E07017059
chr11116511413116511453E07021769
chr11116511549116511839E07021905
chr11116512084116512560E07022440
chr11116512690116512884E07023046
chr11116514293116514450E07024649
chr11116514599116514649E07024955
chr11116515042116515258E07025398
chr11116515262116515312E07025618
chr11116515391116515516E07025747
chr11116515637116515989E07025993
chr11116516018116516098E07026374
chr11116516171116516259E07026527
chr11116521381116521425E07031737
chr11116521995116522543E07032351
chr11116506175116506323E07116531
chr11116506703116506763E07117059
chr11116447997116448107E081-41537
chr11116448375116448464E081-41180
chr11116448519116448940E081-40704
chr11116449035116449085E081-40559
chr11116449394116449451E081-40193
chr11116452790116452979E081-36665
chr11116453026116453188E081-36456
chr11116453368116453574E081-36070
chr11116471794116471847E081-17797
chr11116471896116471946E081-17698
chr11116472337116472458E081-17186
chr11116472556116472712E081-16932
chr11116472846116473125E081-16519
chr11116473322116473508E081-16136
chr11116473690116473767E081-15877
chr11116480808116480858E081-8786
chr11116506175116506323E08116531
chr11116506703116506763E08117059
chr11116449035116449085E082-40559
chr11116449394116449451E082-40193
chr11116452790116452979E082-36665
chr11116472337116472458E082-17186
chr11116472556116472712E082-16932
chr11116472846116473125E082-16519
chr11116473322116473508E082-16136





Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr11116450539116451449E067-38195
chr11116450539116451449E068-38195
chr11116450539116451449E070-38195
chr11116450539116451449E082-38195