rs73017046

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0136 (4071/29912,GnomAD)
A=0131 (3825/29118,TOPMED)
A=0082 (413/5008,1000G)
A=0202 (778/3854,ALSPAC)
A=0204 (756/3708,TWINSUK)
chr6:148560592 (GRCh38.p7) (6q25.1)
AD
GWASCatalog
1   publication(s)
See rs on genome
5 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.148560592G>A
GRCh37.p13 chr 6NC_000006.11:g.148881728G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.949A=0.051
1000GenomesAmericanSub694G=0.900A=0.100
1000GenomesEast AsianSub1008G=0.958A=0.042
1000GenomesEuropeSub1006G=0.819A=0.181
1000GenomesGlobalStudy-wide5008G=0.918A=0.082
1000GenomesSouth AsianSub978G=0.950A=0.050
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.798A=0.202
The Genome Aggregation DatabaseAfricanSub8702G=0.933A=0.067
The Genome Aggregation DatabaseAmericanSub838G=0.910A=0.090
The Genome Aggregation DatabaseEast AsianSub1620G=0.963A=0.037
The Genome Aggregation DatabaseEuropeSub18450G=0.820A=0.179
The Genome Aggregation DatabaseGlobalStudy-wide29912G=0.863A=0.136
The Genome Aggregation DatabaseOtherSub302G=0.870A=0.130
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.868A=0.131
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.796A=0.204
PMID Title Author Journal
29071344Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.Zhou HJAMA Psychiatry

P-Value

SNP ID p-value Traits Study
rs730170466E-06alcohol dependence29071344

eQTL of rs73017046 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs73017046 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6148833868148834049E067-47679
chr6148834053148834152E067-47576
chr6148835645148835821E067-45907
chr6148836022148836089E067-45639
chr6148836111148836195E067-45533
chr6148836598148836672E067-45056
chr6148836935148836985E067-44743
chr6148836994148837083E067-44645
chr6148837291148837724E067-44004
chr6148837824148837996E067-43732
chr6148838192148838252E067-43476
chr6148838381148838582E067-43146
chr6148838588148839062E067-42666
chr6148839235148840895E067-40833
chr6148841364148841701E067-40027
chr6148841750148842017E067-39711
chr6148842114148842193E067-39535
chr6148842324148843412E067-38316
chr6148843783148843833E067-37895
chr6148843920148844023E067-37705
chr6148844077148844127E067-37601
chr6148844247148844518E067-37210
chr6148844675148845037E067-36691
chr6148845697148846934E067-34794
chr6148848456148848506E067-33222
chr6148848724148848827E067-32901
chr6148848906148849005E067-32723
chr6148849123148849173E067-32555
chr6148849447148849748E067-31980
chr6148850210148850250E067-31478
chr6148850323148850478E067-31250
chr6148850627148850697E067-31031
chr6148850753148850803E067-30925
chr6148850972148851022E067-30706
chr6148851328148852398E067-29330
chr6148852490148852795E067-28933
chr6148852997148853051E067-28677
chr6148855369148855477E067-26251
chr6148855523148855591E067-26137
chr6148855870148855954E067-25774
chr6148856170148856214E067-25514
chr6148856215148856277E067-25451
chr6148856368148856408E067-25320
chr6148856454148856572E067-25156
chr6148856830148857529E067-24199
chr6148857802148857848E067-23880
chr6148857898148857974E067-23754
chr6148858232148858312E067-23416
chr6148858384148858519E067-23209
chr6148858674148858740E067-22988
chr6148859001148859108E067-22620
chr6148859116148859285E067-22443
chr6148859335148860289E067-21439
chr6148863866148864584E067-17144
chr6148868304148868628E067-13100
chr6148868845148868925E067-12803
chr6148869042148870214E067-11514
chr6148870249148870561E067-11167
chr6148872027148872221E067-9507
chr6148880209148880647E067-1081
chr6148881729148881919E0671
chr6148887119148888208E0675391
chr6148833868148834049E068-47679
chr6148834053148834152E068-47576
chr6148835645148835821E068-45907
chr6148836022148836089E068-45639
chr6148836111148836195E068-45533
chr6148836935148836985E068-44743
chr6148836994148837083E068-44645
chr6148837291148837724E068-44004
chr6148837824148837996E068-43732
chr6148838192148838252E068-43476
chr6148838381148838582E068-43146
chr6148838588148839062E068-42666
chr6148839235148840895E068-40833
chr6148840931148841252E068-40476
chr6148841364148841701E068-40027
chr6148841750148842017E068-39711
chr6148842114148842193E068-39535
chr6148842324148843412E068-38316
chr6148843783148843833E068-37895
chr6148843920148844023E068-37705
chr6148844077148844127E068-37601
chr6148844247148844518E068-37210
chr6148844675148845037E068-36691
chr6148845697148846934E068-34794
chr6148848724148848827E068-32901
chr6148848906148849005E068-32723
chr6148849123148849173E068-32555
chr6148849447148849748E068-31980
chr6148850210148850250E068-31478
chr6148850323148850478E068-31250
chr6148850627148850697E068-31031
chr6148850753148850803E068-30925
chr6148851328148852398E068-29330
chr6148855182148855253E068-26475
chr6148855369148855477E068-26251
chr6148855523148855591E068-26137
chr6148855870148855954E068-25774
chr6148856170148856214E068-25514
chr6148856215148856277E068-25451
chr6148856368148856408E068-25320
chr6148856454148856572E068-25156
chr6148856830148857529E068-24199
chr6148857802148857848E068-23880
chr6148857898148857974E068-23754
chr6148858232148858312E068-23416
chr6148858384148858519E068-23209
chr6148858674148858740E068-22988
chr6148858788148858897E068-22831
chr6148859001148859108E068-22620
chr6148859116148859285E068-22443
chr6148859335148860289E068-21439
chr6148868304148868628E068-13100
chr6148868845148868925E068-12803
chr6148869042148870214E068-11514
chr6148870249148870561E068-11167
chr6148870683148870765E068-10963
chr6148871768148871993E068-9735
chr6148886372148886447E0684644
chr6148886575148886994E0684847
chr6148887119148888208E0685391
chr6148833868148834049E069-47679
chr6148834053148834152E069-47576
chr6148835645148835821E069-45907
chr6148836022148836089E069-45639
chr6148836111148836195E069-45533
chr6148836598148836672E069-45056
chr6148836935148836985E069-44743
chr6148836994148837083E069-44645
chr6148837291148837724E069-44004
chr6148837824148837996E069-43732
chr6148838192148838252E069-43476
chr6148838381148838582E069-43146
chr6148838588148839062E069-42666
chr6148839235148840895E069-40833
chr6148840931148841252E069-40476
chr6148841364148841701E069-40027
chr6148841750148842017E069-39711
chr6148842114148842193E069-39535
chr6148842324148843412E069-38316
chr6148843783148843833E069-37895
chr6148843920148844023E069-37705
chr6148844077148844127E069-37601
chr6148844247148844518E069-37210
chr6148844675148845037E069-36691
chr6148845697148846934E069-34794
chr6148846963148847049E069-34679
chr6148847846148848001E069-33727
chr6148848456148848506E069-33222
chr6148848724148848827E069-32901
chr6148848906148849005E069-32723
chr6148849123148849173E069-32555
chr6148849447148849748E069-31980
chr6148850210148850250E069-31478
chr6148850323148850478E069-31250
chr6148850627148850697E069-31031
chr6148850753148850803E069-30925
chr6148850972148851022E069-30706
chr6148851328148852398E069-29330
chr6148852997148853051E069-28677
chr6148855369148855477E069-26251
chr6148855523148855591E069-26137
chr6148855870148855954E069-25774
chr6148856170148856214E069-25514
chr6148856215148856277E069-25451
chr6148856368148856408E069-25320
chr6148856454148856572E069-25156
chr6148856830148857529E069-24199
chr6148857802148857848E069-23880
chr6148857898148857974E069-23754
chr6148858232148858312E069-23416
chr6148858384148858519E069-23209
chr6148858674148858740E069-22988
chr6148858788148858897E069-22831
chr6148859001148859108E069-22620
chr6148859116148859285E069-22443
chr6148859335148860289E069-21439
chr6148863866148864584E069-17144
chr6148864815148865004E069-16724
chr6148868304148868628E069-13100
chr6148868845148868925E069-12803
chr6148869042148870214E069-11514
chr6148870249148870561E069-11167
chr6148870683148870765E069-10963
chr6148871768148871993E069-9735
chr6148872027148872221E069-9507
chr6148872411148872498E069-9230
chr6148872536148872689E069-9039
chr6148881729148881919E0691
chr6148899862148899932E06918134
chr6148851328148852398E070-29330
chr6148856454148856572E070-25156
chr6148835645148835821E071-45907
chr6148836022148836089E071-45639
chr6148836111148836195E071-45533
chr6148836598148836672E071-45056
chr6148836935148836985E071-44743
chr6148836994148837083E071-44645
chr6148837291148837724E071-44004
chr6148837824148837996E071-43732
chr6148838192148838252E071-43476
chr6148838381148838582E071-43146
chr6148838588148839062E071-42666
chr6148839235148840895E071-40833
chr6148840931148841252E071-40476
chr6148841364148841701E071-40027
chr6148841750148842017E071-39711
chr6148842114148842193E071-39535
chr6148842324148843412E071-38316
chr6148843783148843833E071-37895
chr6148843920148844023E071-37705
chr6148844077148844127E071-37601
chr6148844247148844518E071-37210
chr6148844675148845037E071-36691
chr6148845065148845219E071-36509
chr6148845290148845378E071-36350
chr6148845411148845490E071-36238
chr6148845553148845667E071-36061
chr6148846963148847049E071-34679
chr6148848724148848827E071-32901
chr6148848906148849005E071-32723
chr6148849123148849173E071-32555
chr6148849447148849748E071-31980
chr6148850210148850250E071-31478
chr6148850323148850478E071-31250
chr6148850627148850697E071-31031
chr6148850753148850803E071-30925
chr6148850972148851022E071-30706
chr6148851328148852398E071-29330
chr6148852490148852795E071-28933
chr6148852997148853051E071-28677
chr6148855369148855477E071-26251
chr6148855523148855591E071-26137
chr6148855870148855954E071-25774
chr6148856170148856214E071-25514
chr6148856215148856277E071-25451
chr6148856368148856408E071-25320
chr6148856454148856572E071-25156
chr6148856830148857529E071-24199
chr6148857802148857848E071-23880
chr6148857898148857974E071-23754
chr6148858232148858312E071-23416
chr6148858384148858519E071-23209
chr6148858674148858740E071-22988
chr6148858788148858897E071-22831
chr6148859001148859108E071-22620
chr6148859116148859285E071-22443
chr6148868304148868628E071-13100
chr6148868845148868925E071-12803
chr6148869042148870214E071-11514
chr6148870249148870561E071-11167
chr6148870683148870765E071-10963
chr6148871768148871993E071-9735
chr6148880209148880647E071-1081
chr6148881729148881919E0711
chr6148833868148834049E072-47679
chr6148834053148834152E072-47576
chr6148835645148835821E072-45907
chr6148836022148836089E072-45639
chr6148836111148836195E072-45533
chr6148836598148836672E072-45056
chr6148836935148836985E072-44743
chr6148836994148837083E072-44645
chr6148837291148837724E072-44004
chr6148837824148837996E072-43732
chr6148838192148838252E072-43476
chr6148838381148838582E072-43146
chr6148838588148839062E072-42666
chr6148839235148840895E072-40833
chr6148840931148841252E072-40476
chr6148841364148841701E072-40027
chr6148841750148842017E072-39711
chr6148842114148842193E072-39535
chr6148842324148843412E072-38316
chr6148844247148844518E072-37210
chr6148845553148845667E072-36061
chr6148845697148846934E072-34794
chr6148848724148848827E072-32901
chr6148848906148849005E072-32723
chr6148849123148849173E072-32555
chr6148849447148849748E072-31980
chr6148850210148850250E072-31478
chr6148850323148850478E072-31250
chr6148850627148850697E072-31031
chr6148850753148850803E072-30925
chr6148850972148851022E072-30706
chr6148851328148852398E072-29330
chr6148852490148852795E072-28933
chr6148852997148853051E072-28677
chr6148855870148855954E072-25774
chr6148856170148856214E072-25514
chr6148856215148856277E072-25451
chr6148856368148856408E072-25320
chr6148856454148856572E072-25156
chr6148856830148857529E072-24199
chr6148857802148857848E072-23880
chr6148857898148857974E072-23754
chr6148858232148858312E072-23416
chr6148858384148858519E072-23209
chr6148858674148858740E072-22988
chr6148858788148858897E072-22831
chr6148859001148859108E072-22620
chr6148859116148859285E072-22443
chr6148863866148864584E072-17144
chr6148868304148868628E072-13100
chr6148868845148868925E072-12803
chr6148869042148870214E072-11514
chr6148870249148870561E072-11167
chr6148871768148871993E072-9735
chr6148872027148872221E072-9507
chr6148872411148872498E072-9230
chr6148872536148872689E072-9039
chr6148899088148899840E07217360
chr6148833868148834049E073-47679
chr6148836022148836089E073-45639
chr6148836111148836195E073-45533
chr6148837291148837724E073-44004
chr6148837824148837996E073-43732
chr6148838192148838252E073-43476
chr6148838381148838582E073-43146
chr6148838588148839062E073-42666
chr6148839235148840895E073-40833
chr6148840931148841252E073-40476
chr6148841364148841701E073-40027
chr6148841750148842017E073-39711
chr6148842114148842193E073-39535
chr6148842324148843412E073-38316
chr6148845553148845667E073-36061
chr6148845697148846934E073-34794
chr6148848724148848827E073-32901
chr6148848906148849005E073-32723
chr6148849123148849173E073-32555
chr6148849447148849748E073-31980
chr6148850210148850250E073-31478
chr6148850323148850478E073-31250
chr6148852490148852795E073-28933
chr6148859116148859285E073-22443
chr6148859335148860289E073-21439
chr6148881729148881919E0731
chr6148899862148899932E07318134
chr6148833868148834049E074-47679
chr6148834053148834152E074-47576
chr6148835645148835821E074-45907
chr6148836022148836089E074-45639
chr6148836111148836195E074-45533
chr6148836598148836672E074-45056
chr6148836935148836985E074-44743
chr6148836994148837083E074-44645
chr6148837291148837724E074-44004
chr6148837824148837996E074-43732
chr6148838192148838252E074-43476
chr6148838381148838582E074-43146
chr6148838588148839062E074-42666
chr6148839235148840895E074-40833
chr6148840931148841252E074-40476
chr6148841364148841701E074-40027
chr6148841750148842017E074-39711
chr6148842114148842193E074-39535
chr6148842324148843412E074-38316
chr6148843783148843833E074-37895
chr6148843920148844023E074-37705
chr6148844077148844127E074-37601
chr6148844247148844518E074-37210
chr6148844675148845037E074-36691
chr6148845065148845219E074-36509
chr6148845290148845378E074-36350
chr6148845411148845490E074-36238
chr6148845553148845667E074-36061
chr6148845697148846934E074-34794
chr6148847686148847827E074-33901
chr6148847846148848001E074-33727
chr6148848456148848506E074-33222
chr6148848724148848827E074-32901
chr6148848906148849005E074-32723
chr6148849123148849173E074-32555
chr6148849447148849748E074-31980
chr6148850210148850250E074-31478
chr6148850323148850478E074-31250
chr6148850627148850697E074-31031
chr6148850753148850803E074-30925
chr6148850972148851022E074-30706
chr6148851328148852398E074-29330
chr6148852490148852795E074-28933
chr6148855870148855954E074-25774
chr6148856170148856214E074-25514
chr6148856215148856277E074-25451
chr6148856368148856408E074-25320
chr6148856454148856572E074-25156
chr6148856830148857529E074-24199
chr6148857802148857848E074-23880
chr6148857898148857974E074-23754
chr6148858232148858312E074-23416
chr6148858384148858519E074-23209
chr6148858674148858740E074-22988
chr6148858788148858897E074-22831
chr6148859001148859108E074-22620
chr6148859116148859285E074-22443
chr6148863866148864584E074-17144
chr6148868105148868161E074-13567
chr6148868304148868628E074-13100
chr6148868845148868925E074-12803
chr6148869042148870214E074-11514
chr6148870249148870561E074-11167
chr6148870683148870765E074-10963
chr6148872411148872498E074-9230
chr6148881729148881919E0741
chr6148886575148886994E0744847
chr6148887119148888208E0745391
chr6148836598148836672E081-45056
chr6148836935148836985E081-44743
chr6148836994148837083E081-44645
chr6148837291148837724E081-44004
chr6148837824148837996E081-43732
chr6148838192148838252E081-43476
chr6148838381148838582E081-43146
chr6148838588148839062E081-42666
chr6148839235148840895E081-40833
chr6148840931148841252E081-40476
chr6148841364148841701E081-40027
chr6148851328148852398E081-29330
chr6148837291148837724E082-44004
chr6148837824148837996E082-43732
chr6148838192148838252E082-43476
chr6148838381148838582E082-43146










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr6148880729148881707E068-21
chr6148880729148881707E069-21
chr6148880729148881707E072-21
chr6148880729148881707E074-21
chr6148880729148881707E082-21