SNP Detail Info-rs73135175

Organism: Homo sapiens

Alleles: C>T

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

T=0153 (4584/29904,GnomAD)
T=0155 (4519/29118,TOPMED)
T=0189 (945/5008,1000G)
T=0183 (704/3854,ALSPAC)
T=0179 (664/3708,TWINSUK)

Position: chr4:45545051 (GRCh38.p7) (4p12)

Phenotype: AD

Dataset:

GWASCatalog

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.45545051C>T
GRCh37.p13 chr 4	NC_000004.11:g.45547068C>T

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.932	T=0.068
1000Genomes	American	Sub	694	C=0.840	T=0.160
1000Genomes	East Asian	Sub	1008	C=0.623	T=0.377
1000Genomes	Europe	Sub	1006	C=0.827	T=0.173
1000Genomes	Global	Study-wide	5008	C=0.811	T=0.189
1000Genomes	South Asian	Sub	978	C=0.810	T=0.190
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.817	T=0.183
The Genome Aggregation Database	African	Sub	8724	C=0.913	T=0.087
The Genome Aggregation Database	American	Sub	832	C=0.810	T=0.190
The Genome Aggregation Database	East Asian	Sub	1596	C=0.602	T=0.398
The Genome Aggregation Database	Europe	Sub	18452	C=0.837	T=0.162
The Genome Aggregation Database	Global	Study-wide	29904	C=0.846	T=0.153
The Genome Aggregation Database	Other	Sub	300	C=0.900	T=0.100
Trans-Omics for Precision Medicine	Global	Study-wide	29118	C=0.844	T=0.155
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.821	T=0.179

PMID	Title	Author	Journal
28990359	Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.	Polimanti R	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs73135175	3E-08	alcohol dependence	28990359

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs73135175