rs7317159

Homo sapiens
T>C
FLT3 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0296 (8872/29916,GnomAD)
C=0300 (8740/29116,TOPMED)
C=0278 (1390/5008,1000G)
C=0271 (1046/3854,ALSPAC)
C=0266 (987/3708,TWINSUK)
chr13:28012083 (GRCh38.p7) (13q12.2)
AD
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.28012083T>C
GRCh37.p13 chr 13NC_000013.10:g.28586220T>C
FLT3 RefSeqGene LRG_457

Gene: FLT3, fms related tyrosine kinase 3(minus strand)

Molecule type Change Amino acid[Codon] SO Term
FLT3 transcript variant 1NM_004119.2:c.N/AIntron Variant
FLT3 transcript variant 2NR_130706.1:n.N/AIntron Variant
FLT3 transcript variant X1XM_011535015.2:c.N/AIntron Variant
FLT3 transcript variant X4XM_011535017.2:c.N/AIntron Variant
FLT3 transcript variant X5XM_011535018.2:c.N/AIntron Variant
FLT3 transcript variant X2XM_017020486.1:c.N/AIntron Variant
FLT3 transcript variant X3XM_017020487.1:c.N/AIntron Variant
FLT3 transcript variant X6XM_017020488.1:c.N/AIntron Variant
FLT3 transcript variant X7XM_017020489.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.617C=0.383
1000GenomesAmericanSub694T=0.760C=0.240
1000GenomesEast AsianSub1008T=0.775C=0.225
1000GenomesEuropeSub1006T=0.713C=0.287
1000GenomesGlobalStudy-wide5008T=0.722C=0.278
1000GenomesSouth AsianSub978T=0.800C=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.729C=0.271
The Genome Aggregation DatabaseAfricanSub8698T=0.644C=0.356
The Genome Aggregation DatabaseAmericanSub830T=0.750C=0.250
The Genome Aggregation DatabaseEast AsianSub1620T=0.783C=0.217
The Genome Aggregation DatabaseEuropeSub18466T=0.721C=0.278
The Genome Aggregation DatabaseGlobalStudy-wide29916T=0.703C=0.296
The Genome Aggregation DatabaseOtherSub302T=0.730C=0.270
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.699C=0.300
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.734C=0.266
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs73171590.000162alcohol dependence21314694

eQTL of rs7317159 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7317159 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr132859682628596943E07110606
chr132859682628596943E07310606
chr132859694628597857E07310726
chr132860118428601655E08114964
chr132860179828601890E08115578