rs7322307

Homo sapiens
A>G
LOC102723490 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0274 (8200/29918,GnomAD)
A==0234 (6814/29116,TOPMED)
A==0239 (1196/5008,1000G)
A==0282 (1088/3854,ALSPAC)
A==0279 (1036/3708,TWINSUK)
chr13:36776542 (GRCh38.p7) (13q13.3)
AD
GWASdb2
1   publication(s)
See rs on genome
40 Enhancers around
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.36776542A>G
GRCh37.p13 chr 13NC_000013.10:g.37350679A>G

Gene: LOC102723490, uncharacterized LOC102723490(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC102723490 transcript variant X2XR_001749823.1:n.N/AIntron Variant
LOC102723490 transcript variant X2XR_001749824.1:n.N/AIntron Variant
LOC102723490 transcript variant X5XR_001749825.1:n.N/AIntron Variant
LOC102723490 transcript variant X9XR_001749828.1:n.N/AIntron Variant
LOC102723490 transcript variant X7XR_001749829.1:n.N/AIntron Variant
LOC102723490 transcript variant X8XR_001749830.1:n.N/AIntron Variant
LOC102723490 transcript variant X11XR_001749832.1:n.N/AIntron Variant
LOC102723490 transcript variant X1XR_941857.2:n.N/AIntron Variant
LOC102723490 transcript variant X5XR_001749826.1:n.N/AGenic Upstream Transcript Variant
LOC102723490 transcript variant X9XR_001749831.1:n.N/AGenic Upstream Transcript Variant
LOC102723490 transcript variant X10XR_941872.2:n.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.187G=0.813
1000GenomesAmericanSub694A=0.330G=0.670
1000GenomesEast AsianSub1008A=0.289G=0.711
1000GenomesEuropeSub1006A=0.282G=0.718
1000GenomesGlobalStudy-wide5008A=0.239G=0.761
1000GenomesSouth AsianSub978A=0.150G=0.850
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.282G=0.718
The Genome Aggregation DatabaseAfricanSub8710A=0.204G=0.796
The Genome Aggregation DatabaseAmericanSub836A=0.350G=0.650
The Genome Aggregation DatabaseEast AsianSub1612A=0.350G=0.650
The Genome Aggregation DatabaseEuropeSub18458A=0.299G=0.700
The Genome Aggregation DatabaseGlobalStudy-wide29918A=0.274G=0.725
The Genome Aggregation DatabaseOtherSub302A=0.130G=0.870
Trans-Omics for Precision MedicineGlobalStudy-wide29116A=0.234G=0.766
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.279G=0.721
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs73223070.00079alcohol dependence20201924

eQTL of rs7322307 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7322307 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr133739526237395319E06744583
chr133739548637395537E06744807
chr133739557337395721E06744894
chr133739700237397132E06746323
chr133739714437397184E06746465
chr133739721237397301E06746533
chr133737834937378435E06827670
chr133739526237395319E06844583
chr133739548637395537E06844807
chr133739557337395721E06844894
chr133739591537395979E07045236
chr133739607737396179E07045398
chr133739661837396668E07045939
chr133739747437397514E07046795
chr133739789037397940E07047211
chr133739797137398032E07047292
chr133739230337392495E07141624
chr133739526237395319E07144583
chr133739548637395537E07144807
chr133739557337395721E07144894
chr133739591537395979E07145236
chr133739700237397132E07146323
chr133739714437397184E07146465
chr133739721237397301E07146533
chr133739230337392495E07441624
chr133739526237395319E07444583
chr133739526237395319E08144583
chr133739548637395537E08144807
chr133739557337395721E08144894
chr133739591537395979E08145236
chr133739607737396179E08145398
chr133739661837396668E08145939
chr133739700237397132E08146323
chr133739714437397184E08146465
chr133739721237397301E08146533
chr133739591537395979E08245236
chr133739700237397132E08246323
chr133739714437397184E08246465
chr133739721237397301E08246533
chr133739747437397514E08246795







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr133739252837394597E06741849
chr133739252837394597E06841849
chr133739252837394597E06941849
chr133739252837394597E07041849
chr133739252837394597E07141849
chr133739252837394597E07241849
chr133739252837394597E07341849
chr133739252837394597E07441849
chr133739252837394597E08241849