rs7333252

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0420 (12549/29840,GnomAD)
T==0412 (12022/29116,TOPMED)
T==0360 (1804/5008,1000G)
T==0404 (1558/3854,ALSPAC)
T==0409 (1517/3708,TWINSUK)
chr13:58774130 (GRCh38.p7) (13q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.58774130T>C
GRCh37.p13 chr 13NC_000013.10:g.59348264T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.453C=0.547
1000GenomesAmericanSub694T=0.400C=0.600
1000GenomesEast AsianSub1008T=0.220C=0.780
1000GenomesEuropeSub1006T=0.429C=0.571
1000GenomesGlobalStudy-wide5008T=0.360C=0.640
1000GenomesSouth AsianSub978T=0.280C=0.720
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.404C=0.596
The Genome Aggregation DatabaseAfricanSub8680T=0.452C=0.548
The Genome Aggregation DatabaseAmericanSub836T=0.420C=0.580
The Genome Aggregation DatabaseEast AsianSub1616T=0.165C=0.835
The Genome Aggregation DatabaseEuropeSub18410T=0.429C=0.570
The Genome Aggregation DatabaseGlobalStudy-wide29840T=0.420C=0.579
The Genome Aggregation DatabaseOtherSub298T=0.340C=0.660
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.412C=0.587
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.409C=0.591
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs73332520.000177alcohol dependence24277619

eQTL of rs7333252 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7333252 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr135930263659302686E081-45578
chr135930295959303009E081-45255
chr135930318559303325E081-44939