rs7336237

Homo sapiens
A>G
USP12-AS2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0062 (1872/29936,GnomAD)
G=0087 (2558/29116,TOPMED)
G=0065 (327/5008,1000G)
G=0015 (58/3854,ALSPAC)
G=0016 (60/3708,TWINSUK)
chr13:27174157 (GRCh38.p7) (13q12.13)
AD
GWASdb2
1   publication(s)
See rs on genome
149 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.27174157A>G
GRCh37.p13 chr 13NC_000013.10:g.27748294A>G

Gene: USP12-AS2, USP12 antisense RNA 2 (head to head)(plus strand)

Molecule type Change Amino acid[Codon] SO Term
USP12-AS2 transcriptNR_046548.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.780G=0.220
1000GenomesAmericanSub694A=0.980G=0.020
1000GenomesEast AsianSub1008A=0.999G=0.001
1000GenomesEuropeSub1006A=0.984G=0.016
1000GenomesGlobalStudy-wide5008A=0.935G=0.065
1000GenomesSouth AsianSub978A=1.000G=0.000
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.985G=0.015
The Genome Aggregation DatabaseAfricanSub8688A=0.810G=0.190
The Genome Aggregation DatabaseAmericanSub838A=0.970G=0.030
The Genome Aggregation DatabaseEast AsianSub1622A=0.999G=0.001
The Genome Aggregation DatabaseEuropeSub18486A=0.989G=0.010
The Genome Aggregation DatabaseGlobalStudy-wide29936A=0.937G=0.062
The Genome Aggregation DatabaseOtherSub302A=1.000G=0.000
Trans-Omics for Precision MedicineGlobalStudy-wide29116A=0.912G=0.087
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.984G=0.016
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs73362370.000696alcohol dependence20201924

eQTL of rs7336237 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7336237 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr132770069627700776E067-47518
chr132770099527701124E067-47170
chr132770116627701216E067-47078
chr132770140027701483E067-46811
chr132770154527701697E067-46597
chr132770179427701890E067-46404
chr132770676027706819E067-41475
chr132770699327707077E067-41217
chr132770707927707215E067-41079
chr132771176627712281E067-36013
chr132771266227712806E067-35488
chr132774194727742175E067-6119
chr132774225727742531E067-5763
chr132774257427742724E067-5570
chr132774307827743685E067-4609
chr132774370627744261E067-4033
chr132770069627700776E068-47518
chr132770099527701124E068-47170
chr132770116627701216E068-47078
chr132770140027701483E068-46811
chr132770154527701697E068-46597
chr132770179427701890E068-46404
chr132770676027706819E068-41475
chr132770699327707077E068-41217
chr132770707927707215E068-41079
chr132770723427707391E068-40903
chr132770741327707470E068-40824
chr132770753427707584E068-40710
chr132771176627712281E068-36013
chr132771266227712806E068-35488
chr132771316527713274E068-35020
chr132774194727742175E068-6119
chr132774225727742531E068-5763
chr132774257427742724E068-5570
chr132774288927742943E068-5351
chr132774307827743685E068-4609
chr132774370627744261E068-4033
chr132770050827700568E069-47726
chr132770069627700776E069-47518
chr132770099527701124E069-47170
chr132770116627701216E069-47078
chr132770140027701483E069-46811
chr132770154527701697E069-46597
chr132770179427701890E069-46404
chr132771176627712281E069-36013
chr132771266227712806E069-35488
chr132774194727742175E069-6119
chr132774225727742531E069-5763
chr132774307827743685E069-4609
chr132774370627744261E069-4033
chr132774225727742531E070-5763
chr132774307827743685E070-4609
chr132774370627744261E070-4033
chr132774721027747396E070-898
chr132770099527701124E071-47170
chr132770116627701216E071-47078
chr132770140027701483E071-46811
chr132770154527701697E071-46597
chr132770179427701890E071-46404
chr132770676027706819E071-41475
chr132770707927707215E071-41079
chr132770723427707391E071-40903
chr132771176627712281E071-36013
chr132771266227712806E071-35488
chr132773796227738026E071-10268
chr132773804027738096E071-10198
chr132773844327738506E071-9788
chr132774225727742531E071-5763
chr132774257427742724E071-5570
chr132774288927742943E071-5351
chr132774307827743685E071-4609
chr132774370627744261E071-4033
chr132774721027747396E071-898
chr132770099527701124E072-47170
chr132770116627701216E072-47078
chr132770676027706819E072-41475
chr132770699327707077E072-41217
chr132770707927707215E072-41079
chr132771176627712281E072-36013
chr132771266227712806E072-35488
chr132771316527713274E072-35020
chr132772599227726730E072-21564
chr132774225727742531E072-5763
chr132774257427742724E072-5570
chr132774288927742943E072-5351
chr132774307827743685E072-4609
chr132774370627744261E072-4033
chr132770069627700776E073-47518
chr132770099527701124E073-47170
chr132770116627701216E073-47078
chr132770140027701483E073-46811
chr132770154527701697E073-46597
chr132770476327705795E073-42499
chr132770603427706158E073-42136
chr132770676027706819E073-41475
chr132770699327707077E073-41217
chr132771176627712281E073-36013
chr132771266227712806E073-35488
chr132774225727742531E073-5763
chr132774257427742724E073-5570
chr132774288927742943E073-5351
chr132774307827743685E073-4609
chr132774370627744261E073-4033
chr132774721027747396E073-898
chr132770069627700776E074-47518
chr132770099527701124E074-47170
chr132770116627701216E074-47078
chr132770140027701483E074-46811
chr132770154527701697E074-46597
chr132770179427701890E074-46404
chr132770676027706819E074-41475
chr132770699327707077E074-41217
chr132770707927707215E074-41079
chr132770723427707391E074-40903
chr132771176627712281E074-36013
chr132771266227712806E074-35488
chr132771316527713274E074-35020
chr132773722427737784E074-10510
chr132773796227738026E074-10268
chr132773804027738096E074-10198
chr132774225727742531E074-5763
chr132774257427742724E074-5570
chr132774288927742943E074-5351
chr132774307827743685E074-4609
chr132774370627744261E074-4033
chr132774721027747396E074-898
chr132769947527699710E081-48584
chr132769971227699819E081-48475
chr132769983627700006E081-48288
chr132770002427700136E081-48158
chr132770069627700776E081-47518
chr132770099527701124E081-47170
chr132770116627701216E081-47078
chr132770140027701483E081-46811
chr132770154527701697E081-46597
chr132770179427701890E081-46404
chr132770352427703584E081-44710
chr132770366827703830E081-44464
chr132770398027704076E081-44218
chr132770413027704273E081-44021
chr132770433527704395E081-43899
chr132770676027706819E081-41475
chr132770699327707077E081-41217
chr132770707927707215E081-41079
chr132774225727742531E081-5763
chr132774257427742724E081-5570
chr132774288927742943E081-5351
chr132774307827743685E081-4609
chr132774225727742531E082-5763










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr132774437627747141E067-1153
chr132774437627747141E068-1153
chr132774437627747141E069-1153
chr132774437627747141E070-1153
chr132774437627747141E071-1153
chr132774437627747141E072-1153
chr132774437627747141E073-1153
chr132774437627747141E074-1153
chr132774437627747141E081-1153
chr132774437627747141E082-1153