rs73477

Homo sapiens
G>A / G>C
None
Check p-value
SNV (Single Nucleotide Variation)
A=0347 (10405/29924,GnomAD)
A=0338 (9843/29118,TOPMED)
A=0349 (1746/5008,1000G)
A=0347 (1336/3854,ALSPAC)
A=0352 (1307/3708,TWINSUK)
chr10:32111468 (GRCh38.p7) (10p11.22)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
29 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.32111468G>A
GRCh38.p7 chr 10NC_000010.11:g.32111468G>C
GRCh37.p13 chr 10NC_000010.10:g.32400396G>A
GRCh37.p13 chr 10NC_000010.10:g.32400396G>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.708A=0.292
1000GenomesAmericanSub694G=0.700A=0.300
1000GenomesEast AsianSub1008G=0.531A=0.469
1000GenomesEuropeSub1006G=0.663A=0.337
1000GenomesGlobalStudy-wide5008G=0.651A=0.349
1000GenomesSouth AsianSub978G=0.650A=0.350
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.653A=0.347
The Genome Aggregation DatabaseAfricanSub8706G=0.699A=0.301
The Genome Aggregation DatabaseAmericanSub838G=0.710A=0.290
The Genome Aggregation DatabaseEast AsianSub1616G=0.541A=0.459
The Genome Aggregation DatabaseEuropeSub18464G=0.637A=0.362
The Genome Aggregation DatabaseGlobalStudy-wide29924G=0.652A=0.347
The Genome Aggregation DatabaseOtherSub300G=0.610A=0.390
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.662A=0.338
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.648A=0.352
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs734770.00014alcohol dependence20201924

eQTL of rs73477 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs73477 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr10119595120326E06714635
chr10122295122751E06717335
chr10119595120326E06814635
chr10122074122270E06817114
chr10122295122751E06817335
chr10122764122872E06817804
chr10119595120326E06914635
chr10122074122270E06917114
chr10122295122751E06917335
chr10119595120326E07014635
chr10120395120445E07015435
chr10122074122270E07017114
chr10122295122751E07017335
chr10119595120326E07114635
chr10122074122270E07117114
chr10122295122751E07117335
chr10122074122270E07217114
chr10122295122751E07217335
chr10119595120326E07314635
chr10122074122270E07317114
chr10122295122751E07317335
chr10119595120326E07414635
chr10122074122270E07417114
chr10122295122751E07417335
chr10119595120326E08214635
chr10120395120445E08215435
chr10122074122270E08217114
chr10122295122751E08217335
chr10122764122872E08217804