rs734826

Homo sapiens
A>C
SHISA9 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0361 (10801/29914,GnomAD)
A==0308 (8974/29118,TOPMED)
A==0330 (1652/5008,1000G)
A==0396 (1526/3854,ALSPAC)
A==0389 (1443/3708,TWINSUK)
chr16:13396523 (GRCh38.p7) (16p13.12)
AD
GWASdb2
2   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.13396523A>C
GRCh37.p13 chr 16NC_000016.9:g.13490380A>C

Gene: SHISA9, shisa family member 9(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SHISA9 transcript variant 1NM_001145204.2:c.N/AGenic Downstream Transcript Variant
SHISA9 transcript variant 2NM_001145205.1:c.N/AGenic Downstream Transcript Variant
SHISA9 transcript variant X2XM_011522642.2:c.N/AIntron Variant
SHISA9 transcript variant X1XM_005255539.3:c.N/AGenic Downstream Transcript Variant
SHISA9 transcript variant X4XR_001751975.1:n.N/AIntron Variant
SHISA9 transcript variant X4XR_001751976.1:n.N/AIntron Variant
SHISA9 transcript variant X3XR_932915.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.163C=0.837
1000GenomesAmericanSub694A=0.510C=0.490
1000GenomesEast AsianSub1008A=0.366C=0.634
1000GenomesEuropeSub1006A=0.437C=0.563
1000GenomesGlobalStudy-wide5008A=0.330C=0.670
1000GenomesSouth AsianSub978A=0.280C=0.720
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.396C=0.604
The Genome Aggregation DatabaseAfricanSub8708A=0.203C=0.797
The Genome Aggregation DatabaseAmericanSub830A=0.530C=0.470
The Genome Aggregation DatabaseEast AsianSub1608A=0.391C=0.609
The Genome Aggregation DatabaseEuropeSub18466A=0.426C=0.573
The Genome Aggregation DatabaseGlobalStudy-wide29914A=0.361C=0.638
The Genome Aggregation DatabaseOtherSub302A=0.280C=0.720
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.308C=0.691
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.389C=0.611
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res
21533127Replication of TCF4 through association and linkage studies in late-onset Fuchs endothelial corneal dystrophy.Li YJPLoS One

P-Value

SNP ID p-value Traits Study
rs7348260.00061alcohol dependence20201924

eQTL of rs734826 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs734826 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr161344521113445264E069-45116
chr161344530013445427E069-44953
chr161344553813445633E069-44747
chr161344572413446090E069-44290