rs736013

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0132 (3958/29930,GnomAD)
C=0103 (2998/29114,TOPMED)
C=0235 (1178/5008,1000G)
C=0093 (359/3854,ALSPAC)
C=0087 (323/3708,TWINSUK)
chr22:42688607 (GRCh38.p7) (22q13.2)
AD
GWASdb2
1   publication(s)
See rs on genome
99 Enhancers around
28 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 22NC_000022.11:g.42688607T>C
GRCh37.p13 chr 22NC_000022.10:g.43084613T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.883C=0.117
1000GenomesAmericanSub694T=0.850C=0.150
1000GenomesEast AsianSub1008T=0.428C=0.572
1000GenomesEuropeSub1006T=0.903C=0.097
1000GenomesGlobalStudy-wide5008T=0.765C=0.235
1000GenomesSouth AsianSub978T=0.750C=0.250
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.907C=0.093
The Genome Aggregation DatabaseAfricanSub8714T=0.910C=0.090
The Genome Aggregation DatabaseAmericanSub838T=0.890C=0.110
The Genome Aggregation DatabaseEast AsianSub1606T=0.423C=0.577
The Genome Aggregation DatabaseEuropeSub18470T=0.884C=0.115
The Genome Aggregation DatabaseGlobalStudy-wide29930T=0.867C=0.132
The Genome Aggregation DatabaseOtherSub302T=0.900C=0.100
Trans-Omics for Precision MedicineGlobalStudy-wide29114T=0.897C=0.103
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.913C=0.087
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs7360130.00015alcohol dependence(early age of onset)20201924
rs7360130.00034alcohol dependence20201924

eQTL of rs736013 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs736013 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr224303881243039344E067-45269
chr224303937343039467E067-45146
chr224303947143039716E067-44897
chr224303972643040119E067-44494
chr224304015343043463E067-41150
chr224307931243080258E067-4355
chr224308026243080527E067-4086
chr224308054643080618E067-3995
chr224308065843080812E067-3801
chr224308083643081082E067-3531
chr224303881243039344E068-45269
chr224303937343039467E068-45146
chr224303947143039716E068-44897
chr224303972643040119E068-44494
chr224304015343043463E068-41150
chr224307931243080258E068-4355
chr224308026243080527E068-4086
chr224308054643080618E068-3995
chr224308065843080812E068-3801
chr224308182243081872E068-2741
chr224308192943083447E068-1166
chr224308363543085260E0680
chr224309103843091089E0686425
chr224309123743091329E0686624
chr224309140643091672E0686793
chr224311773443117834E06833121
chr224303881243039344E069-45269
chr224303937343039467E069-45146
chr224303947143039716E069-44897
chr224303972643040119E069-44494
chr224304015343043463E069-41150
chr224305778243057871E069-26742
chr224306982443070500E069-14113
chr224307916443079267E069-5346
chr224307931243080258E069-4355
chr224308026243080527E069-4086
chr224308054643080618E069-3995
chr224308065843080812E069-3801
chr224303972643040119E070-44494
chr224304015343043463E070-41150
chr224308192943083447E070-1166
chr224308363543085260E0700
chr224303834443038442E071-46171
chr224303881243039344E071-45269
chr224303937343039467E071-45146
chr224303947143039716E071-44897
chr224303972643040119E071-44494
chr224305778243057871E071-26742
chr224306982443070500E071-14113
chr224307931243080258E071-4355
chr224308026243080527E071-4086
chr224308054643080618E071-3995
chr224308065843080812E071-3801
chr224308192943083447E071-1166
chr224308718643087236E0712573
chr224308727543087351E0712662
chr224308747543087628E0712862
chr224303937343039467E072-45146
chr224303947143039716E072-44897
chr224303972643040119E072-44494
chr224304015343043463E072-41150
chr224307931243080258E072-4355
chr224308026243080527E072-4086
chr224308054643080618E072-3995
chr224308065843080812E072-3801
chr224308083643081082E072-3531
chr224309103843091089E0726425
chr224309123743091329E0726624
chr224309140643091672E0726793
chr224309896843099018E07214355
chr224309906043099120E07214447
chr224303881243039344E073-45269
chr224303937343039467E073-45146
chr224303947143039716E073-44897
chr224303972643040119E073-44494
chr224304015343043463E073-41150
chr224306719843067309E073-17304
chr224306734743067779E073-16834
chr224306982443070500E073-14113
chr224307931243080258E073-4355
chr224308026243080527E073-4086
chr224308054643080618E073-3995
chr224308065843080812E073-3801
chr224308192943083447E073-1166
chr224308363543085260E0730
chr224309103843091089E0736425
chr224309123743091329E0736624
chr224303947143039716E074-44897
chr224303972643040119E074-44494
chr224304015343043463E074-41150
chr224306982443070500E074-14113
chr224307931243080258E074-4355
chr224308026243080527E074-4086
chr224308054643080618E074-3995
chr224308065843080812E074-3801
chr224308083643081082E074-3531
chr224308727543087351E0742662
chr224304015343043463E081-41150
chr224305778243057871E082-26742










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr224304384743046047E067-38566
chr224304384743046047E068-38566
chr224304608443046350E068-38263
chr224311501743117629E06830404
chr224304384743046047E069-38566
chr224304608443046350E069-38263
chr224305796043059050E069-25563
chr224311501743117629E06930404
chr224304384743046047E070-38566
chr224304608443046350E070-38263
chr224304384743046047E071-38566
chr224304608443046350E071-38263
chr224305796043059050E071-25563
chr224311501743117629E07130404
chr224304384743046047E072-38566
chr224304608443046350E072-38263
chr224305796043059050E072-25563
chr224311501743117629E07230404
chr224304384743046047E073-38566
chr224304608443046350E073-38263
chr224305796043059050E073-25563
chr224311501743117629E07330404
chr224304384743046047E074-38566
chr224304608443046350E074-38263
chr224311501743117629E07430404
chr224304384743046047E082-38566
chr224304608443046350E082-38263
chr224305796043059050E082-25563