rs73602388

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0015 (455/29940,GnomAD)
T=0023 (696/29118,TOPMED)
T=0015 (74/5008,1000G)
T=0000 (1/3854,ALSPAC)
T=0000 (1/3708,TWINSUK)
chr8:20141801 (GRCh38.p7) (8p21.3)
CD
GWASdb2
1   publication(s)
See rs on genome
9 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.20141801C>T
GRCh37.p13 chr 8NC_000008.10:g.19999312C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.945T=0.055
1000GenomesAmericanSub694C=1.000T=0.000
1000GenomesEast AsianSub1008C=1.000T=0.000
1000GenomesEuropeSub1006C=1.000T=0.000
1000GenomesGlobalStudy-wide5008C=0.985T=0.015
1000GenomesSouth AsianSub978C=1.000T=0.000
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=1.000T=0.000
The Genome Aggregation DatabaseAfricanSub8700C=0.949T=0.051
The Genome Aggregation DatabaseAmericanSub838C=1.000T=0.000
The Genome Aggregation DatabaseEast AsianSub1618C=1.000T=0.000
The Genome Aggregation DatabaseEuropeSub18482C=0.999T=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29940C=0.984T=0.015
The Genome Aggregation DatabaseOtherSub302C=0.990T=0.010
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.976T=0.023
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=1.000T=0.000
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs736023885.79E-05cocaine dependence23958962

eQTL of rs73602388 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs73602388 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr82004606020046167E06846748
chr81998355519984006E070-15306
chr82002917920029280E08129867
chr82002930920029683E08129997
chr82002998320030033E08130671
chr82000204620002098E0822734
chr82000217320002446E0822861
chr82000277320003080E0823461
chr82000310920003383E0823797