rs737505

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0257 (7696/29892,GnomAD)
T=0258 (7530/29118,TOPMED)
T=0182 (911/5008,1000G)
T=0340 (1309/3854,ALSPAC)
T=0325 (1204/3708,TWINSUK)
chr8:41122871 (GRCh38.p7) (8p11.21)
AD
GWASdb2
1   publication(s)
See rs on genome
98 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.41122871C>T
GRCh37.p13 chr 8NC_000008.10:g.40980390C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.796T=0.204
1000GenomesAmericanSub694C=0.800T=0.200
1000GenomesEast AsianSub1008C=0.962T=0.038
1000GenomesEuropeSub1006C=0.695T=0.305
1000GenomesGlobalStudy-wide5008C=0.818T=0.182
1000GenomesSouth AsianSub978C=0.840T=0.160
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.660T=0.340
The Genome Aggregation DatabaseAfricanSub8708C=0.797T=0.203
The Genome Aggregation DatabaseAmericanSub834C=0.840T=0.160
The Genome Aggregation DatabaseEast AsianSub1620C=0.969T=0.031
The Genome Aggregation DatabaseEuropeSub18430C=0.693T=0.306
The Genome Aggregation DatabaseGlobalStudy-wide29892C=0.742T=0.257
The Genome Aggregation DatabaseOtherSub300C=0.680T=0.320
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.741T=0.258
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.675T=0.325
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs7375050.000882alcohol dependence20201924

eQTL of rs737505 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs737505 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr84095664640956823E067-23567
chr84095693340956983E067-23407
chr84095843640959066E067-21324
chr84101535141017103E06734961
chr84101883241019977E06738442
chr84095637340956547E068-23843
chr84095664640956823E068-23567
chr84095693340956983E068-23407
chr84095787740958229E068-22161
chr84095843640959066E068-21324
chr84098310640983258E0682716
chr84098334640983565E0682956
chr84098356640983966E0683176
chr84101535141017103E06834961
chr84095637340956547E069-23843
chr84095664640956823E069-23567
chr84095693340956983E069-23407
chr84095713640957193E069-23197
chr84095728840957389E069-23001
chr84095787740958229E069-22161
chr84095843640959066E069-21324
chr84098356640983966E0693176
chr84100364241004576E06923252
chr84101453841014650E06934148
chr84101479941014926E06934409
chr84101496541015191E06934575
chr84101520341015290E06934813
chr84101535141017103E06934961
chr84093498740935164E070-45226
chr84093525540935870E070-44520
chr84093612640936318E070-44072
chr84093634140936403E070-43987
chr84093649640936624E070-43766
chr84093688640937001E070-43389
chr84093751340937563E070-42827
chr84101883241019977E07038442
chr84095637340956547E071-23843
chr84095664640956823E071-23567
chr84095693340956983E071-23407
chr84095713640957193E071-23197
chr84095728840957389E071-23001
chr84095787740958229E071-22161
chr84095843640959066E071-21324
chr84095920640959298E071-21092
chr84095956740959617E071-20773
chr84097344940973538E071-6852
chr84097360040973654E071-6736
chr84097374640973915E071-6475
chr84098310640983258E0712716
chr84098334640983565E0712956
chr84098356640983966E0713176
chr84101453841014650E07134148
chr84101479941014926E07134409
chr84101496541015191E07134575
chr84101520341015290E07134813
chr84101535141017103E07134961
chr84101883241019977E07138442
chr84094104740941097E072-39293
chr84094110140941225E072-39165
chr84095664640956823E072-23567
chr84095693340956983E072-23407
chr84095713640957193E072-23197
chr84095728840957389E072-23001
chr84095787740958229E072-22161
chr84095843640959066E072-21324
chr84095664640956823E073-23567
chr84095693340956983E073-23407
chr84095713640957193E073-23197
chr84095728840957389E073-23001
chr84095637340956547E074-23843
chr84095664640956823E074-23567
chr84095693340956983E074-23407
chr84095713640957193E074-23197
chr84095728840957389E074-23001
chr84095787740958229E074-22161
chr84095843640959066E074-21324
chr84095920640959298E074-21092
chr84095956740959617E074-20773
chr84096011640960263E074-20127
chr84096026440960595E074-19795
chr84100364241004576E07423252
chr84101479941014926E07434409
chr84101496541015191E07434575
chr84101520341015290E07434813
chr84101535141017103E07434961
chr84095637340956547E081-23843
chr84095664640956823E081-23567
chr84095693340956983E081-23407
chr84101883241019977E08138442
chr84102478541024857E08144395
chr84102491641024995E08144526
chr84093498740935164E082-45226
chr84093525540935870E082-44520
chr84093612640936318E082-44072
chr84093634140936403E082-43987
chr84093649640936624E082-43766
chr84093751340937563E082-42827
chr84101883241019977E08238442