rs737791

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0323 (9667/29924,GnomAD)
A=0319 (9290/29114,TOPMED)
A=0322 (1615/5008,1000G)
A=0318 (1224/3854,ALSPAC)
A=0322 (1195/3708,TWINSUK)
chr22:48061879 (GRCh38.p7) (22q13.31)
AD
GWASdb2
1   publication(s)
See rs on genome
57 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 22NC_000022.11:g.48061879G>A
GRCh37.p13 chr 22NC_000022.10:g.48457696G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.685A=0.315
1000GenomesAmericanSub694G=0.660A=0.340
1000GenomesEast AsianSub1008G=0.638A=0.362
1000GenomesEuropeSub1006G=0.688A=0.312
1000GenomesGlobalStudy-wide5008G=0.678A=0.322
1000GenomesSouth AsianSub978G=0.710A=0.290
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.682A=0.318
The Genome Aggregation DatabaseAfricanSub8712G=0.677A=0.323
The Genome Aggregation DatabaseAmericanSub838G=0.660A=0.340
The Genome Aggregation DatabaseEast AsianSub1610G=0.623A=0.377
The Genome Aggregation DatabaseEuropeSub18462G=0.681A=0.318
The Genome Aggregation DatabaseGlobalStudy-wide29924G=0.676A=0.323
The Genome Aggregation DatabaseOtherSub302G=0.710A=0.290
Trans-Omics for Precision MedicineGlobalStudy-wide29114G=0.680A=0.319
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.678A=0.322
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs7377918.12E-06alcohol dependence21703634

eQTL of rs737791 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs737791 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr224850047248501031E06842776
chr224841365048413700E070-43996
chr224841385948413909E070-43787
chr224841395648414416E070-43280
chr224848552348486430E07227827
chr224841365048413700E081-43996
chr224841385948413909E081-43787
chr224841395648414416E081-43280
chr224842052548420582E081-37114
chr224842085648421449E081-36247
chr224842148848421555E081-36141
chr224843362548433685E081-24011
chr224843372048433834E081-23862
chr224843449748434697E081-22999
chr224843479548434950E081-22746
chr224843530348435353E081-22343
chr224844940748449697E081-7999
chr224845025748450369E081-7327
chr224845039548450445E081-7251
chr224845045048450500E081-7196
chr224845165548451792E081-5904
chr224845183048451927E081-5769
chr224845265848452708E081-4988
chr224845285548453028E081-4668
chr224845342348453626E081-4070
chr224845627248456423E081-1273
chr224845654248456621E081-1075
chr224845796848458034E081272
chr224846421648464646E0816520
chr224846491048464969E0817214
chr224847750848477612E08119812
chr224847763248477682E08119936
chr224847771448477807E08120018
chr224848498648485037E08127290
chr224848504748485132E08127351
chr224849904248499215E08141346
chr224849921848499273E08141522
chr224849930448499474E08141608
chr224849972948499898E08142033
chr224850008948500143E08142393
chr224850047248501031E08142776
chr224850122248501484E08143526
chr224850154848501647E08143852
chr224850192748501977E08144231
chr224841365048413700E082-43996
chr224841385948413909E082-43787
chr224841395648414416E082-43280
chr224842085648421449E082-36247
chr224842148848421555E082-36141
chr224849904248499215E08241346
chr224849921848499273E08241522
chr224849930448499474E08241608
chr224849972948499898E08242033
chr224850008948500143E08242393
chr224850047248501031E08242776
chr224850122248501484E08243526
chr224850154848501647E08243852