rs7404856

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
A==0330 (9883/29942,GnomAD)
A==0314 (9167/29118,TOPMED)
A==0345 (1729/5008,1000G)
chr16:77096442 (GRCh38.p7) (16q23.1)
AD
GWASdb2
1   publication(s)
See rs on genome
24 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.77096442A>C
GRCh37.p13 chr 16NC_000016.9:g.77130339A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.299C=0.701
1000GenomesAmericanSub694A=0.460C=0.540
1000GenomesEast AsianSub1008A=0.318C=0.682
1000GenomesEuropeSub1006A=0.296C=0.704
1000GenomesGlobalStudy-wide5008A=0.345C=0.655
1000GenomesSouth AsianSub978A=0.400C=0.600
The Genome Aggregation DatabaseAfricanSub8710A=0.296C=0.704
The Genome Aggregation DatabaseAmericanSub838A=0.440C=0.560
The Genome Aggregation DatabaseEast AsianSub1614A=0.326C=0.674
The Genome Aggregation DatabaseEuropeSub18478A=0.342C=0.657
The Genome Aggregation DatabaseGlobalStudy-wide29942A=0.330C=0.669
The Genome Aggregation DatabaseOtherSub302A=0.250C=0.750
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.314C=0.685
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs74048560.00098alcohol dependence20201924

eQTL of rs7404856 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr16:77130339SYCE1LENSG00000205078.5A>C1.9155e-9-109999Hypothalamus
Chr16:77130339SYCE1LENSG00000205078.5A>C5.2814e-21-109999Caudate_basal_ganglia
Chr16:77130339SYCE1LENSG00000205078.5A>C1.1510e-14-109999Brain_Spinal_cord_cervical
Chr16:77130339SYCE1LENSG00000205078.5A>C4.1190e-25-109999Putamen_basal_ganglia

meQTL of rs7404856 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr167709666477097291E069-33048
chr167709729277097375E069-32964
chr167709738977097658E069-32681
chr167709768177097779E069-32560
chr167709628077096382E070-33957
chr167709666477097291E070-33048
chr167709729277097375E070-32964
chr167709738977097658E070-32681
chr167709768177097779E070-32560
chr167709784077097914E070-32425
chr167709729277097375E071-32964
chr167709738977097658E071-32681
chr167709768177097779E071-32560
chr167709784077097914E071-32425
chr167709666477097291E073-33048
chr167709729277097375E073-32964
chr167709738977097658E073-32681
chr167709768177097779E073-32560
chr167709738977097658E074-32681
chr167709768177097779E074-32560
chr167709784077097914E074-32425
chr167709738977097658E082-32681
chr167709768177097779E082-32560
chr167709784077097914E082-32425