rs74067914

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0034 (1018/29970,GnomAD)
C=0055 (1616/29118,TOPMED)
C=0038 (192/5008,1000G)
C=0000 (0/3854,ALSPAC)
C=0000 (1/3708,TWINSUK)
chr12:18036994 (GRCh38.p7) (12p12.3)
AD
GWASCatalog
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 12NC_000012.12:g.18036994T>C
GRCh37.p13 chr 12NC_000012.11:g.18189928T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.862C=0.138
1000GenomesAmericanSub694T=0.990C=0.010
1000GenomesEast AsianSub1008T=1.000C=0.000
1000GenomesEuropeSub1006T=0.999C=0.001
1000GenomesGlobalStudy-wide5008T=0.962C=0.038
1000GenomesSouth AsianSub978T=1.000C=0.000
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=1.000C=0.000
The Genome Aggregation DatabaseAfricanSub8718T=0.885C=0.115
The Genome Aggregation DatabaseAmericanSub838T=0.990C=0.010
The Genome Aggregation DatabaseEast AsianSub1622T=1.000C=0.000
The Genome Aggregation DatabaseEuropeSub18490T=0.999C=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29970T=0.966C=0.034
The Genome Aggregation DatabaseOtherSub302T=1.000C=0.000
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.944C=0.055
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=1.000C=0.000
PMID Title Author Journal
29071344Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.Zhou HJAMA Psychiatry

P-Value

SNP ID p-value Traits Study
rs740679147E-06alcohol dependence29071344

eQTL of rs74067914 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs74067914 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr121814463718144755E081-45173
chr121814482218144902E081-45026