rs741000

Homo sapiens
C>T
LOC101927914 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0455 (13634/29910,GnomAD)
T=0475 (13849/29118,TOPMED)
T=0391 (1958/5008,1000G)
T=0496 (1913/3854,ALSPAC)
T=0475 (1762/3708,TWINSUK)
chr7:157485134 (GRCh38.p7) (7q36.3)
AD
GWASdb2
1   publication(s)
See rs on genome
110 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.157485134C>T
GRCh37.p13 chr 7NC_000007.13:g.157277828C>T

Gene: LOC101927914, uncharacterized LOC101927914(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC101927914 transcriptNR_110157.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.524T=0.476
1000GenomesAmericanSub694C=0.660T=0.340
1000GenomesEast AsianSub1008C=0.788T=0.212
1000GenomesEuropeSub1006C=0.511T=0.489
1000GenomesGlobalStudy-wide5008C=0.609T=0.391
1000GenomesSouth AsianSub978C=0.600T=0.400
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.504T=0.496
The Genome Aggregation DatabaseAfricanSub8694C=0.526T=0.474
The Genome Aggregation DatabaseAmericanSub836C=0.670T=0.330
The Genome Aggregation DatabaseEast AsianSub1618C=0.824T=0.176
The Genome Aggregation DatabaseEuropeSub18460C=0.524T=0.475
The Genome Aggregation DatabaseGlobalStudy-wide29910C=0.544T=0.455
The Genome Aggregation DatabaseOtherSub302C=0.430T=0.570
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.524T=0.475
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.525T=0.475
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs7410000.00078alcohol dependence21314694

eQTL of rs741000 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs741000 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7157255362157255517E067-22311
chr7157255589157255639E067-22189
chr7157255736157255870E067-21958
chr7157318185157318245E06740357
chr7157318333157318387E06740505
chr7157318586157319477E06740758
chr7157255136157255303E068-22525
chr7157255362157255517E068-22311
chr7157255589157255639E068-22189
chr7157255736157255870E068-21958
chr7157255894157255944E068-21884
chr7157318586157319477E06840758
chr7157255362157255517E069-22311
chr7157255589157255639E069-22189
chr7157255736157255870E069-21958
chr7157255894157255944E069-21884
chr7157318586157319477E06940758
chr7157254516157254570E070-23258
chr7157254657157254794E070-23034
chr7157254917157255010E070-22818
chr7157255019157255069E070-22759
chr7157255136157255303E070-22525
chr7157255362157255517E070-22311
chr7157255589157255639E070-22189
chr7157255736157255870E070-21958
chr7157255894157255944E070-21884
chr7157256068157256180E070-21648
chr7157259548157259588E070-18240
chr7157259640157259767E070-18061
chr7157259868157259927E070-17901
chr7157260698157260920E070-16908
chr7157277276157277326E070-502
chr7157277469157277516E070-312
chr7157278084157278313E070256
chr7157278349157278409E070521
chr7157279108157279999E0701280
chr7157280268157280318E0702440
chr7157280398157280524E0702570
chr7157291133157291183E07013305
chr7157291433157291550E07013605
chr7157291689157291739E07013861
chr7157318586157319477E07040758
chr7157320057157320142E07042229
chr7157320422157320462E07042594
chr7157320479157320556E07042651
chr7157320858157320908E07043030
chr7157321050157321090E07043222
chr7157255362157255517E071-22311
chr7157255589157255639E071-22189
chr7157255736157255870E071-21958
chr7157256752157257480E071-20348
chr7157257574157257897E071-19931
chr7157255019157255069E072-22759
chr7157255136157255303E072-22525
chr7157255362157255517E072-22311
chr7157255589157255639E072-22189
chr7157255736157255870E072-21958
chr7157255894157255944E072-21884
chr7157318586157319477E07240758
chr7157255136157255303E073-22525
chr7157255362157255517E073-22311
chr7157255589157255639E073-22189
chr7157255736157255870E073-21958
chr7157254917157255010E074-22818
chr7157255019157255069E074-22759
chr7157255136157255303E074-22525
chr7157255362157255517E074-22311
chr7157255589157255639E074-22189
chr7157255736157255870E074-21958
chr7157255894157255944E074-21884
chr7157310743157310793E07432915
chr7157318185157318245E07440357
chr7157318333157318387E07440505
chr7157318586157319477E07440758
chr7157228824157229047E081-48781
chr7157229430157229484E081-48344
chr7157253056157253106E081-24722
chr7157253145157253195E081-24633
chr7157254657157254794E081-23034
chr7157254917157255010E081-22818
chr7157255019157255069E081-22759
chr7157255136157255303E081-22525
chr7157255362157255517E081-22311
chr7157255589157255639E081-22189
chr7157255736157255870E081-21958
chr7157255894157255944E081-21884
chr7157256068157256180E081-21648
chr7157256752157257480E081-20348
chr7157257574157257897E081-19931
chr7157257926157258410E081-19418
chr7157260963157261023E081-16805
chr7157261055157261156E081-16672
chr7157261275157261385E081-16443
chr7157261561157261634E081-16194
chr7157263535157263941E081-13887
chr7157263953157264210E081-13618
chr7157279108157279999E0811280
chr7157280268157280318E0812440
chr7157280398157280524E0812570
chr7157318586157319477E08140758
chr7157320057157320142E08142229
chr7157320422157320462E08142594
chr7157320479157320556E08142651
chr7157255736157255870E082-21958
chr7157256752157257480E082-20348
chr7157257574157257897E082-19931
chr7157257926157258410E082-19418
chr7157259868157259927E082-17901
chr7157263953157264210E082-13618
chr7157318586157319477E08240758