rs7424415

Homo sapiens
T>C
SLC39A10 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0301 (9038/29948,GnomAD)
T==0309 (9001/29118,TOPMED)
T==0393 (1967/5008,1000G)
T==0256 (988/3854,ALSPAC)
T==0245 (907/3708,TWINSUK)
chr2:195671426 (GRCh38.p7) (2q32.3)
AD
GWASdb2
1   publication(s)
See rs on genome
27 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.195671426T>C
GRCh37.p13 chr 2NC_000002.11:g.196536150T>C

Gene: SLC39A10, solute carrier family 39 member 10(plus strand)

Molecule type Change Amino acid[Codon] SO Term
SLC39A10 transcript variant 1NM_001127257.1:c.N/AIntron Variant
SLC39A10 transcript variant 2NM_020342.2:c.N/AIntron Variant
SLC39A10 transcript variant X1XM_005246689.4:c.N/AIntron Variant
SLC39A10 transcript variant X2XM_011511504.2:c.N/AIntron Variant
SLC39A10 transcript variant X4XM_011511505.2:c.N/AIntron Variant
SLC39A10 transcript variant X5XM_011511507.2:c.N/AIntron Variant
SLC39A10 transcript variant X6XM_017004522.1:c.N/AIntron Variant
SLC39A10 transcript variant X7XM_017004523.1:c.N/AIntron Variant
SLC39A10 transcript variant X3XM_011511506.2:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.266C=0.734
1000GenomesAmericanSub694T=0.450C=0.550
1000GenomesEast AsianSub1008T=0.586C=0.414
1000GenomesEuropeSub1006T=0.266C=0.734
1000GenomesGlobalStudy-wide5008T=0.393C=0.607
1000GenomesSouth AsianSub978T=0.450C=0.550
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.256C=0.744
The Genome Aggregation DatabaseAfricanSub8718T=0.279C=0.721
The Genome Aggregation DatabaseAmericanSub836T=0.450C=0.550
The Genome Aggregation DatabaseEast AsianSub1620T=0.623C=0.377
The Genome Aggregation DatabaseEuropeSub18472T=0.275C=0.724
The Genome Aggregation DatabaseGlobalStudy-wide29948T=0.301C=0.698
The Genome Aggregation DatabaseOtherSub302T=0.430C=0.570
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.309C=0.690
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.245C=0.755
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs74244150.0001alcohol dependence20201924

eQTL of rs7424415 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr2:196536150SLC39A10ENSG00000196950.9T>C9.2991e-995449Cerebellum

meQTL of rs7424415 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2196530924196531064E067-5086
chr2196531147196531249E067-4901
chr2196552291196552796E06716141
chr2196571743196571934E06735593
chr2196531147196531249E068-4901
chr2196551759196551919E06815609
chr2196552291196552796E06816141
chr2196532763196532990E069-3160
chr2196530924196531064E070-5086
chr2196531147196531249E070-4901
chr2196551398196551453E07015248
chr2196551579196551657E07015429
chr2196551759196551919E07015609
chr2196552291196552796E07016141
chr2196532763196532990E071-3160
chr2196552291196552796E07116141
chr2196530924196531064E073-5086
chr2196531147196531249E073-4901
chr2196530924196531064E074-5086
chr2196531147196531249E074-4901
chr2196526812196526862E081-9288
chr2196527010196527154E081-8996
chr2196527701196527853E081-8297
chr2196527862196528001E081-8149
chr2196528041196528150E081-8000
chr2196531147196531249E081-4901
chr2196552291196552796E08216141









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr2196520779196524508E067-11642
chr2196520779196524508E068-11642
chr2196520779196524508E069-11642
chr2196520779196524508E070-11642
chr2196520779196524508E071-11642
chr2196520779196524508E072-11642
chr2196520779196524508E073-11642
chr2196520779196524508E074-11642
chr2196520779196524508E081-11642
chr2196520779196524508E082-11642