rs7431326

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0400 (11976/29882,GnomAD)
A=0380 (11083/29118,TOPMED)
A=0399 (2000/5008,1000G)
A=0419 (1614/3854,ALSPAC)
A=0417 (1546/3708,TWINSUK)
chr3:81970452 (GRCh38.p7) (3p12.2)
AD
GWASdb2
1   publication(s)
See rs on genome
45 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.81970452G>A
GRCh37.p13 chr 3NC_000003.11:g.82019603G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.618A=0.382
1000GenomesAmericanSub694G=0.620A=0.380
1000GenomesEast AsianSub1008G=0.567A=0.433
1000GenomesEuropeSub1006G=0.631A=0.369
1000GenomesGlobalStudy-wide5008G=0.601A=0.399
1000GenomesSouth AsianSub978G=0.560A=0.440
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.581A=0.419
The Genome Aggregation DatabaseAfricanSub8678G=0.620A=0.380
The Genome Aggregation DatabaseAmericanSub838G=0.640A=0.360
The Genome Aggregation DatabaseEast AsianSub1610G=0.519A=0.481
The Genome Aggregation DatabaseEuropeSub18454G=0.592A=0.407
The Genome Aggregation DatabaseGlobalStudy-wide29882G=0.599A=0.400
The Genome Aggregation DatabaseOtherSub302G=0.700A=0.300
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.619A=0.380
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.583A=0.417
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs74313260.000649alcohol dependence20201924

eQTL of rs7431326 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7431326 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr38205082482050916E06731221
chr38205197182052759E06732368
chr38205197182052759E06832368
chr38197008581970235E070-49368
chr38197030181970414E070-49189
chr38201446182014511E070-5092
chr38201455082014600E070-5003
chr38201475982014875E070-4728
chr38201495182015145E070-4458
chr38204721682047327E07027613
chr38204737182047863E07027768
chr38204987382050229E07030270
chr38205033782050396E07030734
chr38205054982050681E07030946
chr38205082482050916E07031221
chr38205169782051925E07032094
chr38205197182052759E07032368
chr38205449782054674E07034894
chr38205472882054821E07035125
chr38205494082054990E07035337
chr38205519482055305E07035591
chr38204737182047863E07127768
chr38205169782051925E07332094
chr38205197182052759E07332368
chr38200045682000538E081-19065
chr38204737182047863E08127768
chr38204987382050229E08130270
chr38205033782050396E08130734
chr38205054982050681E08130946
chr38205082482050916E08131221
chr38205169782051925E08132094
chr38205197182052759E08132368
chr38205337182054069E08133768
chr38205449782054674E08134894
chr38205472882054821E08135125
chr38205494082054990E08135337
chr38204737182047863E08227768
chr38204987382050229E08230270
chr38205033782050396E08230734
chr38205054982050681E08230946
chr38205082482050916E08231221
chr38205169782051925E08232094
chr38205197182052759E08232368
chr38205337182054069E08233768
chr38205449782054674E08234894