rs744318

Homo sapiens
T>A / T>G
None
Check p-value
SNV (Single Nucleotide Variation)
T==0369 (11041/29922,GnomAD)
T==0299 (1498/5008,1000G)
T==0389 (1499/3854,ALSPAC)
T==0380 (1410/3708,TWINSUK)
chr15:57589691 (GRCh38.p7) (15q21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.57589691T>A
GRCh38.p7 chr 15NC_000015.10:g.57589691T>G
GRCh37.p13 chr 15NC_000015.9:g.57881889T>A
GRCh37.p13 chr 15NC_000015.9:g.57881889T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.329G=0.671
1000GenomesAmericanSub694T=0.360G=0.640
1000GenomesEast AsianSub1008T=0.084G=0.916
1000GenomesEuropeSub1006T=0.402G=0.598
1000GenomesGlobalStudy-wide5008T=0.299G=0.701
1000GenomesSouth AsianSub978T=0.330G=0.670
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.389G=0.611
The Genome Aggregation DatabaseAfricanSub8706T=0.331G=0.669
The Genome Aggregation DatabaseAmericanSub838T=0.360G=0.64,
The Genome Aggregation DatabaseEast AsianSub1616T=0.082G=0.918
The Genome Aggregation DatabaseEuropeSub18460T=0.414G=0.586
The Genome Aggregation DatabaseGlobalStudy-wide29922T=0.369G=0.630
The Genome Aggregation DatabaseOtherSub302T=0.270G=0.73,
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.380G=0.620
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs7443180.0000036alcoholismpha002892
rs7443180.0000036alcohol dependence(early age of onset)20201924
rs7443180.00021alcohol dependence20201924

eQTL of rs744318 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs744318 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.