rs746486

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0246 (7390/29932,GnomAD)
A=0262 (7653/29118,TOPMED)
A=0316 (1581/5008,1000G)
A=0174 (669/3854,ALSPAC)
A=0186 (690/3708,TWINSUK)
chr5:79802363 (GRCh38.p7) (5q14.1)
AD
GWASdb2
1   publication(s)
See rs on genome
60 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.79802363G>A
GRCh37.p13 chr 5NC_000005.9:g.79098186G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.632A=0.368
1000GenomesAmericanSub694G=0.630A=0.370
1000GenomesEast AsianSub1008G=0.557A=0.443
1000GenomesEuropeSub1006G=0.812A=0.188
1000GenomesGlobalStudy-wide5008G=0.684A=0.316
1000GenomesSouth AsianSub978G=0.800A=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.826A=0.174
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.737A=0.262
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.814A=0.186
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs7464860.000335alcohol dependence21314694

eQTL of rs746486 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs746486 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr57905520879055258E067-42928
chr57905537079055520E067-42666
chr57910261079102855E0674424
chr57913060779130773E06732421
chr57913094079131022E06732754
chr57913362179134100E06735435
chr57913411079134352E06735924
chr57913634879136546E06738162
chr57913657179136646E06738385
chr57913731679137356E06739130
chr57907085179070951E068-27235
chr57910261079102855E0684424
chr57911092179111133E06812735
chr57913601979136225E06837833
chr57913657179136646E06838385
chr57914140579142152E06843219
chr57905520879055258E069-42928
chr57905537079055520E069-42666
chr57907085179070951E069-27235
chr57910261079102855E0694424
chr57912789179128022E06929705
chr57911092179111133E07012735
chr57905520879055258E071-42928
chr57905537079055520E071-42666
chr57911092179111133E07112735
chr57912789179128022E07129705
chr57913016279130302E07131976
chr57913034979130532E07132163
chr57913060779130773E07132421
chr57913094079131022E07132754
chr57913601979136225E07137833
chr57913634879136546E07138162
chr57913657179136646E07138385
chr57914140579142152E07143219
chr57904854179048604E072-49582
chr57904876079048874E072-49312
chr57904895879049250E072-48936
chr57909164979092041E072-6145
chr57910261079102855E0724424
chr57913601979136225E07237833
chr57913634879136546E07238162
chr57913657179136646E07238385
chr57914140579142152E07243219
chr57905520879055258E073-42928
chr57905537079055520E073-42666
chr57910261079102855E0734424
chr57913094079131022E07332754
chr57910261079102855E0744424
chr57911092179111133E07412735
chr57912317079123392E08124984
chr57913004479130134E08131858
chr57913016279130302E08131976
chr57913034979130532E08132163
chr57913060779130773E08132421
chr57913094079131022E08132754
chr57913004479130134E08231858
chr57913016279130302E08231976
chr57913034979130532E08232163
chr57913060779130773E08232421
chr57913094079131022E08232754