SNP Detail Info-rs7468695

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0119 (3585/29936,GnomAD)
G==0110 (3212/29102,TOPMED)
G==0140 (701/5008,1000G)
G==0086 (333/3854,ALSPAC)
G==0084 (311/3708,TWINSUK)

Position: chr9:27234523 (GRCh38.p7) (9p21.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 6 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 9	NC_000009.12:g.27234523G>A
GRCh37.p13 chr 9	NC_000009.11:g.27234521G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.151	A=0.849
1000Genomes	American	Sub	694	G=0.110	A=0.890
1000Genomes	East Asian	Sub	1008	G=0.220	A=0.780
1000Genomes	Europe	Sub	1006	G=0.089	A=0.911
1000Genomes	Global	Study-wide	5008	G=0.140	A=0.860
1000Genomes	South Asian	Sub	978	G=0.120	A=0.880
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.086	A=0.914
The Genome Aggregation Database	African	Sub	8716	G=0.145	A=0.855
The Genome Aggregation Database	American	Sub	834	G=0.160	A=0.840
The Genome Aggregation Database	East Asian	Sub	1614	G=0.224	A=0.776
The Genome Aggregation Database	Europe	Sub	18470	G=0.097	A=0.902
The Genome Aggregation Database	Global	Study-wide	29936	G=0.119	A=0.880
The Genome Aggregation Database	Other	Sub	302	G=0.070	A=0.930
Trans-Omics for Precision Medicine	Global	Study-wide	29102	G=0.110	A=0.889
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.084	A=0.916

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs7468695	0.00046	Alcohol dependence (early age of onset)	20201924
rs7468695	0.00094	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr9	27275922	27276869	E070	41401
chr9	27280256	27280363	E070	45735
chr9	27280378	27280428	E070	45857
chr9	27280256	27280363	E081	45735
chr9	27280378	27280428	E081	45857
chr9	27275922	27276869	E082	41401

rs7468695