rs747915

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0340 (10185/29944,GnomAD)
C=0287 (8365/29118,TOPMED)
C=0243 (1219/5008,1000G)
chr11:121908956 (GRCh38.p7) (11q24.1)
AD
GWASdb2
1   publication(s)
See rs on genome
109 Enhancers around
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.121908956T>C
GRCh37.p13 chr 11NC_000011.9:g.121779664T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.973C=0.027
1000GenomesAmericanSub694T=0.690C=0.310
1000GenomesEast AsianSub1008T=0.733C=0.267
1000GenomesEuropeSub1006T=0.573C=0.427
1000GenomesGlobalStudy-wide5008T=0.757C=0.243
1000GenomesSouth AsianSub978T=0.720C=0.280
The Genome Aggregation DatabaseAfricanSub8722T=0.908C=0.092
The Genome Aggregation DatabaseAmericanSub836T=0.690C=0.310
The Genome Aggregation DatabaseEast AsianSub1614T=0.729C=0.271
The Genome Aggregation DatabaseEuropeSub18470T=0.536C=0.463
The Genome Aggregation DatabaseGlobalStudy-wide29944T=0.659C=0.340
The Genome Aggregation DatabaseOtherSub302T=0.620C=0.380
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.712C=0.287
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs7479150.000321alcohol dependence24277619

eQTL of rs747915 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs747915 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr11121757514121758331E067-21333
chr11121758363121758619E067-21045
chr11121740702121740821E068-38843
chr11121740890121740948E068-38716
chr11121741005121741215E068-38449
chr11121741281121741771E068-37893
chr11121744650121744764E068-34900
chr11121756747121757415E068-22249
chr11121757514121758331E068-21333
chr11121760674121760974E068-18690
chr11121761072121761500E068-18164
chr11121761502121761590E068-18074
chr11121761747121762104E068-17560
chr11121762182121762236E068-17428
chr11121762433121762655E068-17009
chr11121762791121764011E068-15653
chr11121741005121741215E069-38449
chr11121741281121741771E069-37893
chr11121757514121758331E069-21333
chr11121761072121761500E069-18164
chr11121761502121761590E069-18074
chr11121744229121744337E070-35327
chr11121744650121744764E070-34900
chr11121756747121757415E070-22249
chr11121770276121770330E070-9334
chr11121770427121770576E070-9088
chr11121797807121797847E07018143
chr11121797897121798715E07018233
chr11121798901121798955E07019237
chr11121798999121799073E07019335
chr11121799247121799336E07019583
chr11121829232121829307E07049568
chr11121741005121741215E071-38449
chr11121741281121741771E071-37893
chr11121756747121757415E071-22249
chr11121757514121758331E071-21333
chr11121761072121761500E071-18164
chr11121761502121761590E071-18074
chr11121761747121762104E071-17560
chr11121775748121775966E071-3698
chr11121778365121778415E071-1249
chr11121801817121801976E07122153
chr11121802081121802155E07122417
chr11121802196121802322E07122532
chr11121802482121802538E07122818
chr11121761072121761500E072-18164
chr11121761502121761590E072-18074
chr11121761747121762104E072-17560
chr11121762182121762236E072-17428
chr11121762433121762655E072-17009
chr11121801448121801564E07221784
chr11121801571121801617E07221907
chr11121802482121802538E07222818
chr11121802551121803046E07222887
chr11121740702121740821E073-38843
chr11121740890121740948E073-38716
chr11121741005121741215E073-38449
chr11121741281121741771E073-37893
chr11121761072121761500E073-18164
chr11121761502121761590E073-18074
chr11121762182121762236E073-17428
chr11121799247121799336E07319583
chr11121740702121740821E074-38843
chr11121740890121740948E074-38716
chr11121741005121741215E074-38449
chr11121741281121741771E074-37893
chr11121757514121758331E074-21333
chr11121758363121758619E074-21045
chr11121760674121760974E074-18690
chr11121761072121761500E074-18164
chr11121761502121761590E074-18074
chr11121761747121762104E074-17560
chr11121823965121824015E07444301
chr11121740702121740821E081-38843
chr11121740890121740948E081-38716
chr11121741005121741215E081-38449
chr11121741281121741771E081-37893
chr11121756313121756367E081-23297
chr11121756747121757415E081-22249
chr11121757514121758331E081-21333
chr11121758363121758619E081-21045
chr11121758811121759201E081-20463
chr11121794953121795368E08115289
chr11121797721121797775E08118057
chr11121797807121797847E08118143
chr11121797897121798715E08118233
chr11121798901121798955E08119237
chr11121798999121799073E08119335
chr11121799247121799336E08119583
chr11121801448121801564E08121784
chr11121801571121801617E08121907
chr11121820860121820910E08141196
chr11121820957121821202E08141293
chr11121821419121821491E08141755
chr11121821498121821552E08141834
chr11121821554121821612E08141890
chr11121740890121740948E082-38716
chr11121741281121741771E082-37893
chr11121756747121757415E082-22249
chr11121757514121758331E082-21333
chr11121758363121758619E082-21045
chr11121761747121762104E082-17560
chr11121762182121762236E082-17428
chr11121794707121794773E08215043
chr11121797897121798715E08218233
chr11121798901121798955E08219237
chr11121798999121799073E08219335
chr11121799247121799336E08219583
chr11121803313121803723E08223649










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr11121799418121801279E06719754
chr11121799418121801279E06819754
chr11121799418121801279E06919754
chr11121799418121801279E07019754
chr11121799418121801279E07119754
chr11121799418121801279E07219754
chr11121799418121801279E07319754
chr11121799418121801279E07419754
chr11121799418121801279E08219754