rs7489737

Homo sapiens
C>T
LOC105370301 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T=0088 (2635/29932,GnomAD)
T=0098 (2865/29118,TOPMED)
T=0080 (402/5008,1000G)
T=0105 (404/3854,ALSPAC)
T=0103 (382/3708,TWINSUK)
chr13:87021168 (GRCh38.p7) (13q31.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.87021168C>T
GRCh37.p13 chr 13NC_000013.10:g.87673423C>T

Gene: LOC105370301, uncharacterized LOC105370301(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105370301 transcript variant X1XR_931623.2:n.N/AIntron Variant
LOC105370301 transcript variant X2XR_931624.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.899T=0.101
1000GenomesAmericanSub694C=0.930T=0.070
1000GenomesEast AsianSub1008C=0.967T=0.033
1000GenomesEuropeSub1006C=0.906T=0.094
1000GenomesGlobalStudy-wide5008C=0.920T=0.080
1000GenomesSouth AsianSub978C=0.900T=0.100
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.895T=0.105
The Genome Aggregation DatabaseAfricanSub8716C=0.900T=0.100
The Genome Aggregation DatabaseAmericanSub838C=0.940T=0.060
The Genome Aggregation DatabaseEast AsianSub1618C=0.954T=0.046
The Genome Aggregation DatabaseEuropeSub18458C=0.913T=0.086
The Genome Aggregation DatabaseGlobalStudy-wide29932C=0.912T=0.088
The Genome Aggregation DatabaseOtherSub302C=0.850T=0.150
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.901T=0.098
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.897T=0.103
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs74897378.6E-05alcohol consumption23743675

eQTL of rs7489737 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr13:87673423SLITRK5ENSG00000165300.6C>T7.2166e-3-651447Cerebellar_Hemisphere

meQTL of rs7489737 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.