rs7508762

Homo sapiens
T>C
ZNF225 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0173 (5186/29930,GnomAD)
T==0177 (5175/29118,TOPMED)
T==0281 (1408/5008,1000G)
T==0114 (439/3854,ALSPAC)
T==0118 (439/3708,TWINSUK)
chr19:44125725 (GRCh38.p7) (19q13.31)
AD
GWASdb2
1   publication(s)
See rs on genome
29 Enhancers around
60 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 19NC_000019.10:g.44125725T>C
GRCh37.p13 chr 19NC_000019.9:g.44629878T>C

Gene: ZNF225, zinc finger protein 225(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ZNF225 transcript variant 2NM_001321685.1:c.N/AIntron Variant
ZNF225 transcript variant 1NM_013362.3:c.N/AIntron Variant
ZNF225 transcript variant X1XM_011527285.2:c.N/AIntron Variant
ZNF225 transcript variant X2XM_011527286.2:c.N/AIntron Variant
ZNF225 transcript variant X3XM_005259223.3:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.210C=0.790
1000GenomesAmericanSub694T=0.400C=0.600
1000GenomesEast AsianSub1008T=0.496C=0.504
1000GenomesEuropeSub1006T=0.129C=0.871
1000GenomesGlobalStudy-wide5008T=0.281C=0.719
1000GenomesSouth AsianSub978T=0.230C=0.770
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.114C=0.886
The Genome Aggregation DatabaseAfricanSub8712T=0.176C=0.824
The Genome Aggregation DatabaseAmericanSub838T=0.430C=0.570
The Genome Aggregation DatabaseEast AsianSub1614T=0.455C=0.545
The Genome Aggregation DatabaseEuropeSub18466T=0.136C=0.863
The Genome Aggregation DatabaseGlobalStudy-wide29930T=0.173C=0.826
The Genome Aggregation DatabaseOtherSub300T=0.130C=0.870
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.177C=0.822
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.118C=0.882
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs75087628.18E-05alcohol consumption23743675

eQTL of rs7508762 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7508762 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr194467075844670818E06740880
chr194467093344671011E06741055
chr194467104944671115E06741171
chr194461888344619034E068-10844
chr194467075844670818E06840880
chr194467093344671011E06841055
chr194460014844600194E069-29684
chr194460014844600194E070-29684
chr194461888344619034E070-10844
chr194461903744619091E070-10787
chr194461912544619165E070-10713
chr194467075844670818E07040880
chr194467093344671011E07041055
chr194467104944671115E07041171
chr194467187644671938E07041998
chr194461888344619034E071-10844
chr194467075844670818E07140880
chr194467075844670818E07240880
chr194467093344671011E07241055
chr194467075844670818E07440880
chr194467093344671011E07441055
chr194467187644671938E07441998
chr194467075844670818E08140880
chr194467093344671011E08141055
chr194467104944671115E08141171
chr194467187644671938E08141998
chr194460081644600930E082-28948
chr194467093344671011E08241055
chr194467104944671115E08241171









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr194459804744599722E067-30156
chr194461592544616789E067-13089
chr194461680644618482E067-11396
chr194464488144646741E06715003
chr194466849844670041E06738620
chr194459781244597885E068-31993
chr194459793544597989E068-31889
chr194459804744599722E068-30156
chr194461578744615827E068-14051
chr194461592544616789E068-13089
chr194461680644618482E068-11396
chr194464474344644803E06814865
chr194464488144646741E06815003
chr194466849844670041E06838620
chr194459804744599722E069-30156
chr194461578744615827E069-14051
chr194461592544616789E069-13089
chr194461680644618482E069-11396
chr194464488144646741E06915003
chr194466849844670041E06938620
chr194459804744599722E070-30156
chr194461592544616789E070-13089
chr194461680644618482E070-11396
chr194464474344644803E07014865
chr194464488144646741E07015003
chr194466849844670041E07038620
chr194459804744599722E071-30156
chr194461578744615827E071-14051
chr194461592544616789E071-13089
chr194461680644618482E071-11396
chr194464474344644803E07114865
chr194464488144646741E07115003
chr194466849844670041E07138620
chr194459804744599722E072-30156
chr194461592544616789E072-13089
chr194461680644618482E072-11396
chr194464474344644803E07214865
chr194464488144646741E07215003
chr194466849844670041E07238620
chr194459804744599722E073-30156
chr194461592544616789E073-13089
chr194461680644618482E073-11396
chr194464488144646741E07315003
chr194466849844670041E07338620
chr194459804744599722E074-30156
chr194461592544616789E074-13089
chr194461680644618482E074-11396
chr194464488144646741E07415003
chr194466849844670041E07438620
chr194459804744599722E081-30156
chr194461592544616789E081-13089
chr194461680644618482E081-11396
chr194464488144646741E08115003
chr194466849844670041E08138620
chr194459804744599722E082-30156
chr194461592544616789E082-13089
chr194461680644618482E082-11396
chr194464474344644803E08214865
chr194464488144646741E08215003
chr194466849844670041E08238620