rs7517092

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0157 (4705/29976,GnomAD)
C=0185 (5396/29116,TOPMED)
C=0111 (557/5008,1000G)
C=0178 (687/3854,ALSPAC)
C=0170 (629/3708,TWINSUK)
chr1:238607926 (GRCh38.p7) (1q43)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.238607926T>C
GRCh37.p13 chr 1NC_000001.10:g.238771226T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.801C=0.199
1000GenomesAmericanSub694T=0.870C=0.130
1000GenomesEast AsianSub1008T=0.989C=0.011
1000GenomesEuropeSub1006T=0.834C=0.166
1000GenomesGlobalStudy-wide5008T=0.889C=0.111
1000GenomesSouth AsianSub978T=0.970C=0.030
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.822C=0.178
The Genome Aggregation DatabaseAfricanSub8728T=0.815C=0.185
The Genome Aggregation DatabaseAmericanSub838T=0.850C=0.150
The Genome Aggregation DatabaseEast AsianSub1622T=0.972C=0.028
The Genome Aggregation DatabaseEuropeSub18486T=0.845C=0.154
The Genome Aggregation DatabaseGlobalStudy-wide29976T=0.843C=0.157
The Genome Aggregation DatabaseOtherSub302T=0.810C=0.190
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.814C=0.185
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.830C=0.170
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs75170920.000159alcohol dependence20201924

eQTL of rs7517092 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7517092 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.