rs7517505

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0346 (10344/29872,GnomAD)
T==0316 (9223/29118,TOPMED)
T==0389 (1946/5008,1000G)
T==0376 (1451/3854,ALSPAC)
T==0370 (1371/3708,TWINSUK)
chr1:164484136 (GRCh38.p7) (1q23.3)
ND
GWASdb2
1   publication(s)
See rs on genome
33 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.164484136T>C
GRCh37.p13 chr 1NC_000001.10:g.164453373T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.221C=0.779
1000GenomesAmericanSub694T=0.440C=0.560
1000GenomesEast AsianSub1008T=0.614C=0.386
1000GenomesEuropeSub1006T=0.352C=0.648
1000GenomesGlobalStudy-wide5008T=0.389C=0.611
1000GenomesSouth AsianSub978T=0.380C=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.376C=0.624
The Genome Aggregation DatabaseAfricanSub8708T=0.226C=0.774
The Genome Aggregation DatabaseAmericanSub834T=0.480C=0.520
The Genome Aggregation DatabaseEast AsianSub1612T=0.641C=0.359
The Genome Aggregation DatabaseEuropeSub18418T=0.371C=0.628
The Genome Aggregation DatabaseGlobalStudy-wide29872T=0.346C=0.653
The Genome Aggregation DatabaseOtherSub300T=0.340C=0.660
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.316C=0.683
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.370C=0.630
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs75175050.000158nicotine dependence17158188

eQTL of rs7517505 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7517505 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1164484533164484759E06731160
chr1164484975164485125E06731602
chr1164485293164485545E06731920
chr1164487988164488543E06734615
chr1164488836164489003E06735463
chr1164485293164485545E06831920
chr1164485708164485758E06832335
chr1164484533164484759E06931160
chr1164485293164485545E06931920
chr1164487988164488543E06934615
chr1164488836164489003E06935463
chr1164465168164465714E07011795
chr1164465758164465935E07012385
chr1164485293164485545E07031920
chr1164485708164485758E07032335
chr1164487988164488543E07034615
chr1164488836164489003E07035463
chr1164487988164488543E07134615
chr1164488836164489003E07135463
chr1164409285164409913E072-43460
chr1164484533164484759E07231160
chr1164484975164485125E07231602
chr1164485293164485545E07231920
chr1164487988164488543E07234615
chr1164488836164489003E07235463
chr1164484975164485125E07431602
chr1164485293164485545E07431920
chr1164487530164487604E07434157
chr1164487988164488543E07434615
chr1164488836164489003E07435463
chr1164487988164488543E08134615
chr1164487988164488543E08234615
chr1164488836164489003E08235463