rs7532171

Organism: Homo sapiens

Alleles: C>T

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

T=0136 (4088/29960,GnomAD)
T=0125 (3665/29118,TOPMED)
T=0180 (901/5008,1000G)
T=0083 (320/3854,ALSPAC)
T=0095 (353/3708,TWINSUK)

Position: chr1:101259395 (GRCh38.p7) (1p21.2)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 19 Enhancers around

Promoter: 34 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 1	NC_000001.11:g.101259395C>T
GRCh37.p13 chr 1	NC_000001.10:g.101724951C>T

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.846	T=0.154
1000Genomes	American	Sub	694	C=0.880	T=0.120
1000Genomes	East Asian	Sub	1008	C=0.571	T=0.429
1000Genomes	Europe	Sub	1006	C=0.884	T=0.116
1000Genomes	Global	Study-wide	5008	C=0.820	T=0.180
1000Genomes	South Asian	Sub	978	C=0.940	T=0.060
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.917	T=0.083
The Genome Aggregation Database	African	Sub	8712	C=0.844	T=0.156
The Genome Aggregation Database	American	Sub	836	C=0.840	T=0.160
The Genome Aggregation Database	East Asian	Sub	1608	C=0.602	T=0.398
The Genome Aggregation Database	Europe	Sub	18502	C=0.896	T=0.103
The Genome Aggregation Database	Global	Study-wide	29960	C=0.863	T=0.136
The Genome Aggregation Database	Other	Sub	302	C=0.900	T=0.100
Trans-Omics for Precision Medicine	Global	Study-wide	29118	C=0.874	T=0.125
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.905	T=0.095

PMID	Title	Author	Journal
20158304	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.	Lind PA	Twin Res Hum Genet

SNP ID	p-value	Traits	Study
rs7532171	3.81E-05	alcohol and nictotine co-dependence	20158304

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

There is no significant Hi-C chromatin interaction data for this SNP.

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr1	101756040	101756631	E068	31089
chr1	101756673	101756777	E068	31722
chr1	101728583	101728713	E069	3632
chr1	101682895	101682975	E070	-41976
chr1	101684909	101685089	E070	-39862
chr1	101685204	101685262	E070	-39689
chr1	101685582	101685813	E070	-39138
chr1	101685895	101686150	E070	-38801
chr1	101749060	101749302	E070	24109
chr1	101723944	101724056	E071	-895
chr1	101727751	101727877	E071	2800
chr1	101753708	101754529	E071	28757
chr1	101757056	101757555	E071	32105
chr1	101757581	101757703	E071	32630
chr1	101753708	101754529	E072	28757
chr1	101728583	101728713	E074	3632
chr1	101685204	101685262	E081	-39689
chr1	101685582	101685813	E081	-39138
chr1	101685895	101686150	E081	-38801

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr1	101700692	101703534	E067	-21417
chr1	101703586	101705585	E067	-19366
chr1	101705618	101706118	E067	-18833
chr1	101706187	101706324	E067	-18627
chr1	101700692	101703534	E068	-21417
chr1	101703586	101705585	E068	-19366
chr1	101705618	101706118	E068	-18833
chr1	101706187	101706324	E068	-18627
chr1	101706363	101706411	E068	-18540
chr1	101700692	101703534	E069	-21417
chr1	101703586	101705585	E069	-19366
chr1	101703586	101705585	E070	-19366
chr1	101705618	101706118	E070	-18833
chr1	101706187	101706324	E070	-18627
chr1	101706363	101706411	E070	-18540
chr1	101700692	101703534	E071	-21417
chr1	101703586	101705585	E071	-19366
chr1	101705618	101706118	E071	-18833
chr1	101706187	101706324	E071	-18627
chr1	101706363	101706411	E071	-18540
chr1	101700692	101703534	E072	-21417
chr1	101703586	101705585	E072	-19366
chr1	101700692	101703534	E073	-21417
chr1	101703586	101705585	E073	-19366
chr1	101705618	101706118	E073	-18833
chr1	101700692	101703534	E074	-21417
chr1	101703586	101705585	E074	-19366
chr1	101705618	101706118	E074	-18833
chr1	101706187	101706324	E074	-18627
chr1	101706363	101706411	E074	-18540
chr1	101700692	101703534	E082	-21417
chr1	101703586	101705585	E082	-19366
chr1	101705618	101706118	E082	-18833
chr1	101706187	101706324	E082	-18627