rs7544843

Homo sapiens
G>A
DAB1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0375 (11211/29884,GnomAD)
A=0363 (10581/29118,TOPMED)
A=0379 (1899/5008,1000G)
A=0415 (1601/3854,ALSPAC)
A=0418 (1550/3708,TWINSUK)
chr1:57798095 (GRCh38.p7) (1p32.2)
AD
GWASdb2
1   publication(s)
See rs on genome
25 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.57798095G>A
GRCh37.p13 chr 1NC_000001.10:g.58263767G>A
DAB1 RefSeqGeneNG_046914.1:g.457445C>T

Gene: DAB1, DAB1, reelin adaptor protein(minus strand)

Molecule type Change Amino acid[Codon] SO Term
DAB1 transcriptNM_021080.3:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.720A=0.280
1000GenomesAmericanSub694G=0.690A=0.310
1000GenomesEast AsianSub1008G=0.658A=0.342
1000GenomesEuropeSub1006G=0.542A=0.458
1000GenomesGlobalStudy-wide5008G=0.621A=0.379
1000GenomesSouth AsianSub978G=0.480A=0.520
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.585A=0.415
The Genome Aggregation DatabaseAfricanSub8700G=0.723A=0.277
The Genome Aggregation DatabaseAmericanSub830G=0.700A=0.300
The Genome Aggregation DatabaseEast AsianSub1620G=0.649A=0.351
The Genome Aggregation DatabaseEuropeSub18432G=0.575A=0.424
The Genome Aggregation DatabaseGlobalStudy-wide29884G=0.624A=0.375
The Genome Aggregation DatabaseOtherSub302G=0.490A=0.510
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.636A=0.363
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.582A=0.418
PMID Title Author Journal
24962325Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.Kapoor MDrug Alcohol Depend

P-Value

SNP ID p-value Traits Study
rs75448433.53E-06alcohol dependence (age at onset)24962325

eQTL of rs7544843 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7544843 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr15821445858214716E070-49051
chr15830491758305054E07041150
chr15830532558305379E07041558
chr15821445858214716E071-49051
chr15826108058261130E081-2637
chr15826121458261264E081-2503
chr15826235558262622E081-1145
chr15826393458263994E081167
chr15826406158264201E081294
chr15826433358264655E081566
chr15826470558264782E081938
chr15826482858264954E0811061
chr15826506258265210E0811295
chr15826526758265698E0811500
chr15826614258266244E0812375
chr15826647458266570E0812707
chr15826665758266780E0812890
chr15826701558267133E0813248
chr15824525458245437E082-18330
chr15826235558262622E082-1145
chr15826393458263994E082167
chr15826614258266244E0822375
chr15826892458269013E0825157
chr15829238158292512E08228614
chr15829267058292748E08228903