rs7550193

Homo sapiens
G>C
None
Check p-value
SNV (Single Nucleotide Variation)
G==0345 (10356/29940,GnomAD)
G==0317 (9237/29118,TOPMED)
G==0389 (1947/5008,1000G)
G==0376 (1450/3854,ALSPAC)
G==0368 (1366/3708,TWINSUK)
chr1:164483505 (GRCh38.p7) (1q23.3)
ND
GWASdb2
1   publication(s)
See rs on genome
33 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.164483505G>C
GRCh37.p13 chr 1NC_000001.10:g.164452742G>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.222C=0.778
1000GenomesAmericanSub694G=0.440C=0.560
1000GenomesEast AsianSub1008G=0.614C=0.386
1000GenomesEuropeSub1006G=0.352C=0.648
1000GenomesGlobalStudy-wide5008G=0.389C=0.611
1000GenomesSouth AsianSub978G=0.380C=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.376C=0.624
The Genome Aggregation DatabaseAfricanSub8724G=0.227C=0.773
The Genome Aggregation DatabaseAmericanSub838G=0.480C=0.520
The Genome Aggregation DatabaseEast AsianSub1612G=0.638C=0.362
The Genome Aggregation DatabaseEuropeSub18464G=0.370C=0.629
The Genome Aggregation DatabaseGlobalStudy-wide29940G=0.345C=0.654
The Genome Aggregation DatabaseOtherSub302G=0.350C=0.650
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.317C=0.682
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.368C=0.632
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs75501930.000147nicotine dependence17158188

eQTL of rs7550193 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7550193 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1164484533164484759E06731791
chr1164484975164485125E06732233
chr1164485293164485545E06732551
chr1164487988164488543E06735246
chr1164488836164489003E06736094
chr1164485293164485545E06832551
chr1164485708164485758E06832966
chr1164484533164484759E06931791
chr1164485293164485545E06932551
chr1164487988164488543E06935246
chr1164488836164489003E06936094
chr1164465168164465714E07012426
chr1164465758164465935E07013016
chr1164485293164485545E07032551
chr1164485708164485758E07032966
chr1164487988164488543E07035246
chr1164488836164489003E07036094
chr1164487988164488543E07135246
chr1164488836164489003E07136094
chr1164409285164409913E072-42829
chr1164484533164484759E07231791
chr1164484975164485125E07232233
chr1164485293164485545E07232551
chr1164487988164488543E07235246
chr1164488836164489003E07236094
chr1164484975164485125E07432233
chr1164485293164485545E07432551
chr1164487530164487604E07434788
chr1164487988164488543E07435246
chr1164488836164489003E07436094
chr1164487988164488543E08135246
chr1164487988164488543E08235246
chr1164488836164489003E08236094