rs7556950

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0083 (2509/29950,GnomAD)
C=0076 (2237/29116,TOPMED)
C=0087 (437/5008,1000G)
C=0046 (176/3854,ALSPAC)
C=0049 (181/3708,TWINSUK)
chr2:41582921 (GRCh38.p7) (2p21)
AD
GWASCatalog
1   publication(s)
See rs on genome
10 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.41582921T>C
GRCh37.p13 chr 2NC_000002.11:g.41810061T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.865C=0.135
1000GenomesAmericanSub694T=0.970C=0.030
1000GenomesEast AsianSub1008T=0.856C=0.144
1000GenomesEuropeSub1006T=0.950C=0.050
1000GenomesGlobalStudy-wide5008T=0.913C=0.087
1000GenomesSouth AsianSub978T=0.960C=0.040
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.954C=0.046
The Genome Aggregation DatabaseAfricanSub8722T=0.877C=0.123
The Genome Aggregation DatabaseAmericanSub838T=0.980C=0.020
The Genome Aggregation DatabaseEast AsianSub1608T=0.820C=0.180
The Genome Aggregation DatabaseEuropeSub18480T=0.939C=0.060
The Genome Aggregation DatabaseGlobalStudy-wide29950T=0.916C=0.083
The Genome Aggregation DatabaseOtherSub302T=0.960C=0.040
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.923C=0.076
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.951C=0.049
PMID Title Author Journal
29071344Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.Zhou HJAMA Psychiatry

P-Value

SNP ID p-value Traits Study
rs75569508E-06alcohol dependence29071344

eQTL of rs7556950 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7556950 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr24182487341825730E06714812
chr24184886241848942E07038801
chr24182487341825730E07114812
chr24182487341825730E07214812
chr24182487341825730E07414812
chr24182487341825730E08114812
chr24183805441838501E08127993
chr24182487341825730E08214812
chr24182622241826320E08216161
chr24183805441838501E08227993