rs7566309

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0157 (4711/29932,GnomAD)
A==0159 (4652/29116,TOPMED)
A==0163 (814/5008,1000G)
A==0141 (542/3854,ALSPAC)
A==0137 (509/3708,TWINSUK)
chr2:39869258 (GRCh38.p7) (2p22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
18 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.39869258A>G
GRCh37.p13 chr 2NC_000002.11:g.40096398A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.191G=0.809
1000GenomesAmericanSub694A=0.170G=0.830
1000GenomesEast AsianSub1008A=0.129G=0.871
1000GenomesEuropeSub1006A=0.134G=0.866
1000GenomesGlobalStudy-wide5008A=0.163G=0.837
1000GenomesSouth AsianSub978A=0.180G=0.820
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.141G=0.859
The Genome Aggregation DatabaseAfricanSub8700A=0.201G=0.799
The Genome Aggregation DatabaseAmericanSub836A=0.170G=0.830
The Genome Aggregation DatabaseEast AsianSub1610A=0.171G=0.829
The Genome Aggregation DatabaseEuropeSub18484A=0.136G=0.863
The Genome Aggregation DatabaseGlobalStudy-wide29932A=0.157G=0.842
The Genome Aggregation DatabaseOtherSub302A=0.090G=0.910
Trans-Omics for Precision MedicineGlobalStudy-wide29116A=0.159G=0.840
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.137G=0.863
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs75663090.0006alcohol dependence24277619

eQTL of rs7566309 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7566309 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr24007835340078403E067-17995
chr24007854340078607E067-17791
chr24009736840097471E068970
chr24009811240099161E0681714
chr24010232440102672E0685926
chr24010288440103185E0686486
chr24007854340078607E069-17791
chr24007835340078403E070-17995
chr24007854340078607E070-17791
chr24007887540079264E070-17134
chr24007854340078607E071-17791
chr24007887540079264E071-17134
chr24009797840098087E0731580
chr24009811240099161E0731714
chr24007835340078403E081-17995
chr24007887540079264E081-17134
chr24014079340141485E08144395
chr24007887540079264E082-17134