SNP Detail Info-rs7573381

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

LOC101927967 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0339 (10149/29920,GnomAD)
G=0390 (11373/29116,TOPMED)
G=0329 (1649/5008,1000G)
G=0258 (994/3854,ALSPAC)
G=0254 (940/3708,TWINSUK)

Position: chr2:78078496 (GRCh38.p7) (2p12)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 8 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.78078496A>G
GRCh37.p13 chr 2	NC_000002.11:g.78305622A>G

Molecule type	Change	Amino acid[Codon]	SO Term
LOC101927967 transcript	NR_110288.1:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.328	G=0.672
1000Genomes	American	Sub	694	A=0.800	G=0.200
1000Genomes	East Asian	Sub	1008	A=0.844	G=0.156
1000Genomes	Europe	Sub	1006	A=0.792	G=0.208
1000Genomes	Global	Study-wide	5008	A=0.671	G=0.329
1000Genomes	South Asian	Sub	978	A=0.740	G=0.260
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.742	G=0.258
The Genome Aggregation Database	African	Sub	8708	A=0.400	G=0.600
The Genome Aggregation Database	American	Sub	832	A=0.800	G=0.200
The Genome Aggregation Database	East Asian	Sub	1616	A=0.833	G=0.167
The Genome Aggregation Database	Europe	Sub	18462	A=0.760	G=0.240
The Genome Aggregation Database	Global	Study-wide	29920	A=0.660	G=0.339
The Genome Aggregation Database	Other	Sub	302	A=0.810	G=0.190
Trans-Omics for Precision Medicine	Global	Study-wide	29116	A=0.609	G=0.390
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.746	G=0.254

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs7573381	0.00063	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	78354560	78354935	E067	48938
chr2	78354390	78354522	E068	48768
chr2	78304829	78305092	E069	-530
chr2	78305357	78305485	E069	-137
chr2	78354390	78354522	E071	48768
chr2	78354560	78354935	E071	48938
chr2	78354560	78354935	E072	48938
chr2	78354560	78354935	E074	48938

rs7573381