rs75792394

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0146 (4390/29982,GnomAD)
T=0146 (4260/29116,TOPMED)
T=0149 (745/5008,1000G)
T=0116 (447/3854,ALSPAC)
T=0117 (432/3708,TWINSUK)
chr2:62381943 (GRCh38.p7) (2p15)
CD
GWASdb2
1   publication(s)
See rs on genome
61 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.62381943G>T
GRCh37.p13 chr 2NC_000002.11:g.62609078G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.828T=0.172
1000GenomesAmericanSub694G=0.800T=0.200
1000GenomesEast AsianSub1008G=0.886T=0.114
1000GenomesEuropeSub1006G=0.862T=0.138
1000GenomesGlobalStudy-wide5008G=0.851T=0.149
1000GenomesSouth AsianSub978G=0.870T=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.884T=0.116
The Genome Aggregation DatabaseAfricanSub8726G=0.835T=0.165
The Genome Aggregation DatabaseAmericanSub838G=0.800T=0.200
The Genome Aggregation DatabaseEast AsianSub1616G=0.882T=0.118
The Genome Aggregation DatabaseEuropeSub18500G=0.862T=0.137
The Genome Aggregation DatabaseGlobalStudy-wide29982G=0.853T=0.146
The Genome Aggregation DatabaseOtherSub302G=0.830T=0.170
Trans-Omics for Precision MedicineGlobalStudy-wide29116G=0.853T=0.146
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.883T=0.117
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs757923946.47E-06cocaine dependence23958962

eQTL of rs75792394 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs75792394 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr26263644062636535E06727362
chr26263659562637210E06727517
chr26263723662637473E06728158
chr26263747462637568E06728396
chr26263795562639547E06728877
chr26265091062650990E06741832
chr26265135662651532E06742278
chr26265211062652332E06743032
chr26263613062636358E06827052
chr26263644062636535E06827362
chr26263659562637210E06827517
chr26263723662637473E06828158
chr26263747462637568E06828396
chr26263795562639547E06828877
chr26264224562642444E06833167
chr26264258362642723E06833505
chr26265091062650990E06841832
chr26265135662651532E06842278
chr26265211062652332E06843032
chr26263659562637210E06927517
chr26263723662637473E06928158
chr26263747462637568E06928396
chr26263795562639547E06928877
chr26265091062650990E06941832
chr26265135662651532E06942278
chr26265211062652332E06943032
chr26256124162561421E070-47657
chr26256149062561540E070-47538
chr26256177162561823E070-47255
chr26265135662651532E07042278
chr26263723662637473E07128158
chr26263747462637568E07128396
chr26263795562639547E07128877
chr26265091062650990E07141832
chr26265211062652332E07143032
chr26263659562637210E07227517
chr26263723662637473E07228158
chr26263747462637568E07228396
chr26263795562639547E07228877
chr26265091062650990E07241832
chr26263659562637210E07327517
chr26263723662637473E07328158
chr26263747462637568E07328396
chr26263795562639547E07328877
chr26265135662651532E07342278
chr26265211062652332E07343032
chr26263723662637473E07428158
chr26263747462637568E07428396
chr26263795562639547E07428877
chr26263956162639919E07430483
chr26263993362639983E07430855
chr26264207962642227E07433001
chr26265044362650676E07441365
chr26265091062650990E07441832
chr26265135662651532E07442278
chr26265211062652332E07443032
chr26263795562639547E08128877
chr26263956162639919E08130483
chr26256124162561421E082-47657
chr26256149062561540E082-47538
chr26263795562639547E08228877