SNP Detail Info-rs7603576

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

LOC105373718 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0198 (5924/29922,GnomAD)
G=0197 (5757/29118,TOPMED)
G=0181 (907/5008,1000G)
G=0227 (876/3854,ALSPAC)
G=0221 (821/3708,TWINSUK)

Position: chr2:160575093 (GRCh38.p7) (2q24.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.160575093A>G
GRCh37.p13 chr 2	NC_000002.11:g.161431604A>G

Molecule type	Change	Amino acid[Codon]	SO Term
LOC105373718 transcript	XR_923526.2:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.875	G=0.125
1000Genomes	American	Sub	694	A=0.610	G=0.390
1000Genomes	East Asian	Sub	1008	A=0.978	G=0.022
1000Genomes	Europe	Sub	1006	A=0.767	G=0.233
1000Genomes	Global	Study-wide	5008	A=0.819	G=0.181
1000Genomes	South Asian	Sub	978	A=0.780	G=0.220
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.773	G=0.227
The Genome Aggregation Database	African	Sub	8712	A=0.847	G=0.153
The Genome Aggregation Database	American	Sub	836	A=0.620	G=0.380
The Genome Aggregation Database	East Asian	Sub	1618	A=0.975	G=0.025
The Genome Aggregation Database	Europe	Sub	18456	A=0.774	G=0.225
The Genome Aggregation Database	Global	Study-wide	29922	A=0.802	G=0.198
The Genome Aggregation Database	Other	Sub	300	A=0.730	G=0.270
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.802	G=0.197
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.779	G=0.221

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs7603576	0.0000465	alcoholism	pha002892
rs7603576	0.000047	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs7603576