rs7605261

Homo sapiens
T>G
CTNNA2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0444 (13258/29814,GnomAD)
G=0442 (12892/29116,TOPMED)
G=0446 (2233/5008,1000G)
G=0421 (1622/3854,ALSPAC)
G=0422 (1563/3708,TWINSUK)
chr2:80544065 (GRCh38.p7) (2p12)
AD
GWASdb2
1   publication(s)
See rs on genome
8 Enhancers around
4 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.80544065T>G
GRCh37.p13 chr 2NC_000002.11:g.80771190T>G

Gene: CTNNA2, catenin alpha 2(plus strand)

Molecule type Change Amino acid[Codon] SO Term
CTNNA2 transcript variant 2NM_001164883.1:c.N/AIntron Variant
CTNNA2 transcript variant 3NM_001282597.2:c.N/AIntron Variant
CTNNA2 transcript variant 4NM_001282598.1:c.N/AIntron Variant
CTNNA2 transcript variant 5NM_001282599.1:c.N/AIntron Variant
CTNNA2 transcript variant 6NM_001282600.1:c.N/AIntron Variant
CTNNA2 transcript variant 7NM_001320810.1:c.N/AIntron Variant
CTNNA2 transcript variant 1NM_004389.3:c.N/AIntron Variant
CTNNA2 transcript variant X4XM_011532555.2:c.N/AIntron Variant
CTNNA2 transcript variant X2XM_011532556.2:c.N/AIntron Variant
CTNNA2 transcript variant X9XM_011532557.2:c.N/AIntron Variant
CTNNA2 transcript variant X3XM_017003403.1:c.N/AIntron Variant
CTNNA2 transcript variant X4XM_017003404.1:c.N/AIntron Variant
CTNNA2 transcript variant X5XM_017003405.1:c.N/AIntron Variant
CTNNA2 transcript variant X7XM_017003406.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.535G=0.465
1000GenomesAmericanSub694T=0.610G=0.390
1000GenomesEast AsianSub1008T=0.654G=0.346
1000GenomesEuropeSub1006T=0.574G=0.426
1000GenomesGlobalStudy-wide5008T=0.554G=0.446
1000GenomesSouth AsianSub978T=0.420G=0.580
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.579G=0.421
The Genome Aggregation DatabaseAfricanSub8686T=0.528G=0.472
The Genome Aggregation DatabaseAmericanSub834T=0.590G=0.410
The Genome Aggregation DatabaseEast AsianSub1604T=0.691G=0.309
The Genome Aggregation DatabaseEuropeSub18388T=0.552G=0.447
The Genome Aggregation DatabaseGlobalStudy-wide29814T=0.555G=0.444
The Genome Aggregation DatabaseOtherSub302T=0.670G=0.330
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.557G=0.442
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.578G=0.422
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs76052610.000573alcohol dependence20201924

eQTL of rs7605261 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7605261 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr28074716480747238E067-23952
chr28074716480747238E068-23952
chr28074642880746491E069-24699
chr28077570280775926E0694512
chr28081838380818465E07047193
chr28074642880746491E072-24699
chr28074716480747238E072-23952
chr28077570280775926E0824512






Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr28081594080816430E07244750
chr28081659480816653E07245404
chr28081594080816430E07344750
chr28081659480816653E07345404