SNP Detail Info-rs7607774

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0076 (2283/29970,GnomAD)
A=0079 (2322/29118,TOPMED)
A=0144 (720/5008,1000G)
A=0026 (99/3854,ALSPAC)
A=0033 (121/3708,TWINSUK)

Position: chr2:236520511 (GRCh38.p7) (2q37.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 16 Enhancers around

Promoter: 27 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.236520511G>A
GRCh37.p13 chr 2	NC_000002.11:g.237429154G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.853	A=0.147
1000Genomes	American	Sub	694	G=0.840	A=0.160
1000Genomes	East Asian	Sub	1008	G=0.698	A=0.302
1000Genomes	Europe	Sub	1006	G=0.960	A=0.040
1000Genomes	Global	Study-wide	5008	G=0.856	A=0.144
1000Genomes	South Asian	Sub	978	G=0.930	A=0.070
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.974	A=0.026
The Genome Aggregation Database	African	Sub	8720	G=0.889	A=0.111
The Genome Aggregation Database	American	Sub	838	G=0.860	A=0.140
The Genome Aggregation Database	East Asian	Sub	1616	G=0.709	A=0.291
The Genome Aggregation Database	Europe	Sub	18494	G=0.961	A=0.038
The Genome Aggregation Database	Global	Study-wide	29970	G=0.923	A=0.076
The Genome Aggregation Database	Other	Sub	302	G=0.960	A=0.040
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.920	A=0.079
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.967	A=0.033

PMID	Title	Author	Journal
21956439	Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.	Zuo L	Neuropsychopharmacology

SNP ID	p-value	Traits	Study
rs7607774	4E-07	alcohol dependence	21956439

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	237414660	237414719	E067	-14435
chr2	237413729	237413977	E068	-15177
chr2	237468059	237468109	E068	38905
chr2	237410348	237410595	E069	-18559
chr2	237412451	237412522	E071	-16632
chr2	237413475	237413525	E071	-15629
chr2	237413729	237413977	E071	-15177
chr2	237466643	237466811	E071	37489
chr2	237466934	237467036	E071	37780
chr2	237413475	237413525	E072	-15629
chr2	237413729	237413977	E072	-15177
chr2	237407331	237407381	E073	-21773
chr2	237414660	237414719	E073	-14435
chr2	237466643	237466811	E074	37489
chr2	237412451	237412522	E081	-16632
chr2	237414660	237414719	E082	-14435

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr2	237415887	237416511	E067	-12643
chr2	237416594	237416644	E067	-12510
chr2	237416662	237416714	E067	-12440
chr2	237415887	237416511	E068	-12643
chr2	237416594	237416644	E068	-12510
chr2	237416662	237416714	E068	-12440
chr2	237476012	237476545	E068	46858
chr2	237415887	237416511	E069	-12643
chr2	237416594	237416644	E069	-12510
chr2	237416662	237416714	E069	-12440
chr2	237415887	237416511	E070	-12643
chr2	237416594	237416644	E070	-12510
chr2	237415887	237416511	E071	-12643
chr2	237416594	237416644	E071	-12510
chr2	237416662	237416714	E071	-12440
chr2	237415887	237416511	E072	-12643
chr2	237416594	237416644	E072	-12510
chr2	237416662	237416714	E072	-12440
chr2	237415887	237416511	E073	-12643
chr2	237416594	237416644	E073	-12510
chr2	237416662	237416714	E073	-12440
chr2	237476012	237476545	E073	46858
chr2	237415887	237416511	E074	-12643
chr2	237416594	237416644	E074	-12510
chr2	237415887	237416511	E081	-12643
chr2	237415887	237416511	E082	-12643
chr2	237416594	237416644	E082	-12510

rs7607774