rs761516

Homo sapiens
T>C / T>G
None
Check p-value
SNV (Single Nucleotide Variation)
T==0275 (8240/29930,GnomAD)
T==0329 (9605/29118,TOPMED)
T==0273 (1366/5008,1000G)
T==0200 (771/3854,ALSPAC)
T==0201 (746/3708,TWINSUK)
chr1:186992194 (GRCh38.p7) (1q31.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.186992194T>C
GRCh38.p7 chr 1NC_000001.11:g.186992194T>G
GRCh37.p13 chr 1NC_000001.10:g.186961326T>C
GRCh37.p13 chr 1NC_000001.10:g.186961326T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.533G=0.467
1000GenomesAmericanSub694T=0.280G=0.720
1000GenomesEast AsianSub1008T=0.119G=0.881
1000GenomesEuropeSub1006T=0.208G=0.792
1000GenomesGlobalStudy-wide5008T=0.273G=0.727
1000GenomesSouth AsianSub978T=0.140G=0.860
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.200G=0.800
The Genome Aggregation DatabaseAfricanSub8704T=0.485G=0.515
The Genome Aggregation DatabaseAmericanSub836T=0.270G=0.73,
The Genome Aggregation DatabaseEast AsianSub1618T=0.142G=0.858
The Genome Aggregation DatabaseEuropeSub18470T=0.190G=0.809
The Genome Aggregation DatabaseGlobalStudy-wide29930T=0.275G=0.724
The Genome Aggregation DatabaseOtherSub302T=0.170G=0.83,
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.329G=0.670
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.201G=0.799
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs7615165.15E-05alcohol dependence21314694

eQTL of rs761516 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs761516 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr12597576625975809E067-49947
chr12598014925980296E067-45460
chr12598409925984260E067-41496
chr12598444025984480E067-41276
chr12598482225984999E067-40757
chr12598535825985985E067-39771
chr12598798525988309E067-37447
chr12599931525999671E067-26085
chr12600016826000282E067-25474
chr12600030026000366E067-25390
chr12600224326003034E067-22722
chr12600305026003314E067-22442
chr12600334926003428E067-22328
chr12600370226003752E067-22004
chr12600383026004093E067-21663
chr12600974926009800E067-15956
chr12600984926010064E067-15692
chr12601033626010523E067-15233
chr12601081926010977E067-14779
chr12602055226022786E067-2970
chr12602386626023965E067-1791
chr12602402026024591E067-1165
chr12602490526025190E067-566
chr12602607226026261E067316
chr12602629826026641E067542
chr12602668326026947E067927
chr12602704226027441E0671286
chr12602799826028062E0672242
chr12602867126029091E0672915
chr12602937726029512E0673621
chr12603063726031398E0674881
chr12603312226033304E0677366
chr12603362626035128E0677870
chr12605070626051129E06724950
chr12605236126052411E06726605
chr12605267026052736E06726914
chr12605311926053169E06727363
chr12605343926053489E06727683
chr12605358126053937E06727825
chr12605402726054825E06728271
chr12605485326055000E06729097
chr12605516126055221E06729405
chr12605634426056629E06730588
chr12605669026056870E06730934
chr12605691826057222E06731162
chr12605732526057524E06731569
chr12606371826063933E06737962
chr12606938226069476E06743626
chr12606974826071394E06743992
chr12597576625975809E068-49947
chr12597651925976666E068-49090
chr12597679925976875E068-48881
chr12597843425978531E068-47225
chr12597859225978649E068-47107
chr12597866025978736E068-47020
chr12597874625979006E068-46750
chr12597901325979174E068-46582
chr12598211425982165E068-43591
chr12598379325983985E068-41771
chr12598409925984260E068-41496
chr12598444025984480E068-41276
chr12598482225984999E068-40757
chr12598535825985985E068-39771
chr12599102225991192E068-34564
chr12599124225991502E068-34254
chr12599621825996274E068-29482
chr12600224326003034E068-22722
chr12600305026003314E068-22442
chr12600334926003428E068-22328
chr12600974926009800E068-15956
chr12600984926010064E068-15692
chr12601033626010523E068-15233
chr12601081926010977E068-14779
chr12601273426012840E068-12916
chr12602055226022786E068-2970
chr12602278826022889E068-2867
chr12602350626023582E068-2174
chr12602371726023791E068-1965
chr12602386626023965E068-1791
chr12602402026024591E068-1165
chr12602607226026261E068316
chr12602629826026641E068542
chr12602668326026947E068927
chr12602704226027441E0681286
chr12602799826028062E0682242
chr12603063726031398E0684881
chr12605402726054825E06828271
chr12605485326055000E06829097
chr12605516126055221E06829405
chr12606329026063507E06837534
chr12606371826063933E06837962
chr12606938226069476E06843626
chr12606974826071394E06843992
chr12597576625975809E069-49947
chr12597651925976666E069-49090
chr12597679925976875E069-48881
chr12597843425978531E069-47225
chr12597859225978649E069-47107
chr12597866025978736E069-47020
chr12597874625979006E069-46750
chr12597901325979174E069-46582
chr12598104625981103E069-44653
chr12598142225981796E069-43960
chr12598379325983985E069-41771
chr12598409925984260E069-41496
chr12598444025984480E069-41276
chr12598482225984999E069-40757
chr12598535825985985E069-39771
chr12598602325986136E069-39620
chr12600305026003314E069-22442
chr12600334926003428E069-22328
chr12600370226003752E069-22004
chr12600868626008790E069-16966
chr12600974926009800E069-15956
chr12600984926010064E069-15692
chr12601033626010523E069-15233
chr12601081926010977E069-14779
chr12601490926015580E069-10176
chr12602012626020322E069-5434
chr12602055226022786E069-2970
chr12602278826022889E069-2867
chr12602402026024591E069-1165
chr12602490526025190E069-566
chr12602607226026261E069316
chr12602629826026641E069542
chr12602668326026947E069927
chr12602704226027441E0691286
chr12602799826028062E0692242
chr12604033226040412E06914576
chr12604041826040487E06914662
chr12604059926040653E06914843
chr12605153426051837E06925778
chr12605215126052226E06926395
chr12605226926052319E06926513
chr12605236126052411E06926605
chr12605267026052736E06926914
chr12605311926053169E06927363
chr12605343926053489E06927683
chr12605358126053937E06927825
chr12605402726054825E06928271
chr12605485326055000E06929097
chr12605516126055221E06929405
chr12605691826057222E06931162
chr12605732526057524E06931569
chr12606371826063933E06937962
chr12606938226069476E06943626
chr12606974826071394E06943992
chr12597576625975809E070-49947
chr12597866025978736E070-47020
chr12599079125990966E070-34790
chr12599102225991192E070-34564
chr12599124225991502E070-34254
chr12599153425991589E070-34167
chr12599169625991803E070-33953
chr12599254825992592E070-33164
chr12599283025992880E070-32876
chr12599290425993016E070-32740
chr12599302025993335E070-32421
chr12599336725993556E070-32200
chr12599359525993666E070-32090
chr12599404425994084E070-31672
chr12599413625994216E070-31540
chr12599441125994903E070-30853
chr12600305026003314E070-22442
chr12600334926003428E070-22328
chr12600984926010064E070-15692
chr12601033626010523E070-15233
chr12601081926010977E070-14779
chr12601127026011323E070-14433
chr12601156426011648E070-14108
chr12602607226026261E070316
chr12602629826026641E070542
chr12602668326026947E070927
chr12602704226027441E0701286
chr12602799826028062E0702242
chr12603281726032972E0707061
chr12603298426033063E0707228
chr12603312226033304E0707366
chr12603336626033457E0707610
chr12603353526033599E0707779
chr12603362626035128E0707870
chr12604033226040412E07014576
chr12604041826040487E07014662
chr12604059926040653E07014843
chr12604099726041231E07015241
chr12605122526051516E07025469
chr12605153426051837E07025778
chr12605402726054825E07028271
chr12605669026056870E07030934
chr12605691826057222E07031162
chr12597576625975809E071-49947
chr12597651925976666E071-49090
chr12597679925976875E071-48881
chr12597722525977275E071-48481
chr12597778425977908E071-47848
chr12597795625978000E071-47756
chr12597843425978531E071-47225
chr12597859225978649E071-47107
chr12597866025978736E071-47020
chr12597874625979006E071-46750
chr12597901325979174E071-46582
chr12597994925980073E071-45683
chr12598014925980296E071-45460
chr12598104625981103E071-44653
chr12598142225981796E071-43960
chr12598379325983985E071-41771
chr12598409925984260E071-41496
chr12598444025984480E071-41276
chr12598482225984999E071-40757
chr12598535825985985E071-39771
chr12600224326003034E071-22722
chr12600305026003314E071-22442
chr12600334926003428E071-22328
chr12600984926010064E071-15692
chr12601033626010523E071-15233
chr12601081926010977E071-14779
chr12602012626020322E071-5434
chr12602055226022786E071-2970
chr12602278826022889E071-2867
chr12602386626023965E071-1791
chr12602402026024591E071-1165
chr12602607226026261E071316
chr12602629826026641E071542
chr12602704226027441E0711286
chr12602799826028062E0712242
chr12602867126029091E0712915
chr12602937726029512E0713621
chr12603063726031398E0714881
chr12603143226031517E0715676
chr12603169826031738E0715942
chr12603265226032782E0716896
chr12605153426051837E07125778
chr12605215126052226E07126395
chr12605226926052319E07126513
chr12605236126052411E07126605
chr12605267026052736E07126914
chr12605311926053169E07127363
chr12605343926053489E07127683
chr12605358126053937E07127825
chr12605402726054825E07128271
chr12605485326055000E07129097
chr12605516126055221E07129405
chr12605691826057222E07131162
chr12605732526057524E07131569
chr12606270126062921E07136945
chr12606329026063507E07137534
chr12606371826063933E07137962
chr12606938226069476E07143626
chr12606974826071394E07143992
chr12607518326075323E07149427
chr12607542026075592E07149664
chr12597576625975809E072-49947
chr12597778425977908E072-47848
chr12597795625978000E072-47756
chr12597843425978531E072-47225
chr12597859225978649E072-47107
chr12597866025978736E072-47020
chr12597874625979006E072-46750
chr12597901325979174E072-46582
chr12598142225981796E072-43960
chr12598211425982165E072-43591
chr12598379325983985E072-41771
chr12598409925984260E072-41496
chr12598444025984480E072-41276
chr12598482225984999E072-40757
chr12598535825985985E072-39771
chr12598765725987883E072-37873
chr12600224326003034E072-22722
chr12600305026003314E072-22442
chr12600334926003428E072-22328
chr12600370226003752E072-22004
chr12600383026004093E072-21663
chr12600974926009800E072-15956
chr12600984926010064E072-15692
chr12601033626010523E072-15233
chr12601081926010977E072-14779
chr12601479726014857E072-10899
chr12601490926015580E072-10176
chr12602012626020322E072-5434
chr12602055226022786E072-2970
chr12602490526025190E072-566
chr12602607226026261E072316
chr12602629826026641E072542
chr12602668326026947E072927
chr12602704226027441E0721286
chr12602799826028062E0722242
chr12602867126029091E0722915
chr12602937726029512E0723621
chr12603063726031398E0724881
chr12603281726032972E0727061
chr12603298426033063E0727228
chr12603312226033304E0727366
chr12603336626033457E0727610
chr12603353526033599E0727779
chr12605215126052226E07226395
chr12605226926052319E07226513
chr12605236126052411E07226605
chr12605267026052736E07226914
chr12605402726054825E07228271
chr12605485326055000E07229097
chr12605516126055221E07229405
chr12606329026063507E07237534
chr12606371826063933E07237962
chr12606938226069476E07243626
chr12606974826071394E07243992
chr12607389826074137E07248142
chr12607518326075323E07249427
chr12607542026075592E07249664
chr12597576625975809E073-49947
chr12597651925976666E073-49090
chr12597679925976875E073-48881
chr12597722525977275E073-48481
chr12597778425977908E073-47848
chr12597795625978000E073-47756
chr12597843425978531E073-47225
chr12597859225978649E073-47107
chr12597866025978736E073-47020
chr12597874625979006E073-46750
chr12597901325979174E073-46582
chr12598379325983985E073-41771
chr12598409925984260E073-41496
chr12598444025984480E073-41276
chr12598482225984999E073-40757
chr12598535825985985E073-39771
chr12598765725987883E073-37873
chr12598798525988309E073-37447
chr12600016826000282E073-25474
chr12600030026000366E073-25390
chr12600305026003314E073-22442
chr12600334926003428E073-22328
chr12600370226003752E073-22004
chr12600383026004093E073-21663
chr12600974926009800E073-15956
chr12600984926010064E073-15692
chr12601033626010523E073-15233
chr12601081926010977E073-14779
chr12601490926015580E073-10176
chr12602012626020322E073-5434
chr12602055226022786E073-2970
chr12602278826022889E073-2867
chr12602490526025190E073-566
chr12602607226026261E073316
chr12602629826026641E073542
chr12602668326026947E073927
chr12602704226027441E0731286
chr12602799826028062E0732242
chr12602867126029091E0732915
chr12602937726029512E0733621
chr12603063726031398E0734881
chr12603143226031517E0735676
chr12603169826031738E0735942
chr12603265226032782E0736896
chr12603281726032972E0737061
chr12603298426033063E0737228
chr12603312226033304E0737366
chr12603336626033457E0737610
chr12603650326036913E07310747
chr12603713526037936E07311379
chr12605215126052226E07326395
chr12605226926052319E07326513
chr12605236126052411E07326605
chr12605343926053489E07327683
chr12605358126053937E07327825
chr12605402726054825E07328271
chr12605485326055000E07329097
chr12605516126055221E07329405
chr12606329026063507E07337534
chr12606371826063933E07337962
chr12606938226069476E07343626
chr12606974826071394E07343992
chr12607149126071599E07345735
chr12607389826074137E07348142
chr12607450426074554E07348748
chr12607518326075323E07349427
chr12597576625975809E074-49947
chr12597651925976666E074-49090
chr12597843425978531E074-47225
chr12597859225978649E074-47107
chr12597866025978736E074-47020
chr12597874625979006E074-46750
chr12597901325979174E074-46582
chr12597994925980073E074-45683
chr12598014925980296E074-45460
chr12598104625981103E074-44653
chr12598142225981796E074-43960
chr12598379325983985E074-41771
chr12598409925984260E074-41496
chr12598444025984480E074-41276
chr12598482225984999E074-40757
chr12598535825985985E074-39771
chr12600224326003034E074-22722
chr12600305026003314E074-22442
chr12600334926003428E074-22328
chr12600868626008790E074-16966
chr12600974926009800E074-15956
chr12600984926010064E074-15692
chr12601033626010523E074-15233
chr12601273426012840E074-12916
chr12601285026012982E074-12774
chr12601479726014857E074-10899
chr12601490926015580E074-10176
chr12602055226022786E074-2970
chr12602402026024591E074-1165
chr12602607226026261E074316
chr12602629826026641E074542
chr12602668326026947E074927
chr12602704226027441E0741286
chr12602799826028062E0742242
chr12603063726031398E0744881
chr12603265226032782E0746896
chr12603281726032972E0747061
chr12603298426033063E0747228
chr12603312226033304E0747366
chr12605215126052226E07426395
chr12605226926052319E07426513
chr12605236126052411E07426605
chr12605267026052736E07426914
chr12605311926053169E07427363
chr12605343926053489E07427683
chr12605358126053937E07427825
chr12605402726054825E07428271
chr12605485326055000E07429097
chr12606329026063507E07437534
chr12606371826063933E07437962
chr12606938226069476E07443626
chr12606974826071394E07443992
chr12597576625975809E081-49947
chr12597651925976666E081-49090
chr12597679925976875E081-48881
chr12597778425977908E081-47848
chr12597795625978000E081-47756
chr12597843425978531E081-47225
chr12597859225978649E081-47107
chr12597866025978736E081-47020
chr12597874625979006E081-46750
chr12597901325979174E081-46582
chr12597994925980073E081-45683
chr12598014925980296E081-45460
chr12599254825992592E081-33164
chr12599283025992880E081-32876
chr12599290425993016E081-32740
chr12599302025993335E081-32421
chr12599336725993556E081-32200
chr12599359525993666E081-32090
chr12600224326003034E081-22722
chr12600305026003314E081-22442
chr12600334926003428E081-22328
chr12600370226003752E081-22004
chr12600383026004093E081-21663
chr12601033626010523E081-15233
chr12601479726014857E081-10899
chr12601490926015580E081-10176
chr12601570626015750E081-10006
chr12602012626020322E081-5434
chr12602055226022786E081-2970
chr12602278826022889E081-2867
chr12602386626023965E081-1791
chr12602402026024591E081-1165
chr12602607226026261E081316
chr12602629826026641E081542
chr12602668326026947E081927
chr12602704226027441E0811286
chr12602799826028062E0812242
chr12602867126029091E0812915
chr12602937726029512E0813621
chr12603063726031398E0814881
chr12603143226031517E0815676
chr12603169826031738E0815942
chr12605402726054825E08128271
chr12605485326055000E08129097
chr12605516126055221E08129405
chr12605634426056629E08130588
chr12605669026056870E08130934
chr12605691826057222E08131162
chr12606974826071394E08143992
chr12607321526073266E08147459
chr12607389826074137E08148142
chr12607450426074554E08148748
chr12607518326075323E08149427
chr12607542026075592E08149664
chr12597576625975809E082-49947
chr12597722525977275E082-48481
chr12597778425977908E082-47848
chr12597795625978000E082-47756
chr12597843425978531E082-47225
chr12597859225978649E082-47107
chr12597866025978736E082-47020
chr12597874625979006E082-46750
chr12597901325979174E082-46582
chr12597994925980073E082-45683
chr12599124225991502E082-34254
chr12599153425991589E082-34167
chr12599169625991803E082-33953
chr12599254825992592E082-33164
chr12599283025992880E082-32876
chr12599290425993016E082-32740
chr12599302025993335E082-32421
chr12599336725993556E082-32200
chr12599359525993666E082-32090
chr12600224326003034E082-22722
chr12600305026003314E082-22442
chr12600334926003428E082-22328
chr12600984926010064E082-15692
chr12601033626010523E082-15233
chr12601081926010977E082-14779
chr12601127026011323E082-14433
chr12601156426011648E082-14108
chr12602055226022786E082-2970
chr12602278826022889E082-2867
chr12602607226026261E082316
chr12602629826026641E082542
chr12602668326026947E082927
chr12602704226027441E0821286
chr12602799826028062E0822242
chr12603063726031398E0824881
chr12605122526051516E08225469
chr12605153426051837E08225778
chr12605402726054825E08228271
chr12605485326055000E08229097
chr12605516126055221E08229405
chr12605669026056870E08230934
chr12605691826057222E08231162
chr12605732526057524E08231569
chr12607149126071599E08245735
chr12607389826074137E08248142
chr12607450426074554E08248748
chr12607518326075323E08249427
chr12607542026075592E08249664