rs7627066

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0414 (12413/29936,GnomAD)
G=0424 (12369/29118,TOPMED)
G=0426 (2135/5008,1000G)
G=0403 (1552/3854,ALSPAC)
G=0393 (1457/3708,TWINSUK)
chr3:194512024 (GRCh38.p7) (3q29)
AD
GWASdb2
1   publication(s)
See rs on genome
59 Enhancers around
18 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.194512024T>G
GRCh37.p13 chr 3NC_000003.11:g.194232753T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.583G=0.417
1000GenomesAmericanSub694T=0.560G=0.440
1000GenomesEast AsianSub1008T=0.573G=0.427
1000GenomesEuropeSub1006T=0.567G=0.433
1000GenomesGlobalStudy-wide5008T=0.574G=0.426
1000GenomesSouth AsianSub978T=0.580G=0.420
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.597G=0.403
The Genome Aggregation DatabaseAfricanSub8710T=0.556G=0.444
The Genome Aggregation DatabaseAmericanSub838T=0.530G=0.470
The Genome Aggregation DatabaseEast AsianSub1616T=0.554G=0.446
The Genome Aggregation DatabaseEuropeSub18470T=0.604G=0.395
The Genome Aggregation DatabaseGlobalStudy-wide29936T=0.585G=0.414
The Genome Aggregation DatabaseOtherSub302T=0.610G=0.390
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.575G=0.424
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.607G=0.393
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs76270660.000879alcohol consumption (maxi-drinks)24277619

eQTL of rs7627066 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7627066 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3194218502194218824E067-13929
chr3194219044194219518E067-13235
chr3194257766194258944E06725013
chr3194197584194197868E068-34885
chr3194257766194258944E06825013
chr3194269356194270017E06836603
chr3194277127194277633E06844374
chr3194196340194196408E069-36345
chr3194196429194196557E069-36196
chr3194196612194197352E069-35401
chr3194269356194270017E07036603
chr3194196340194196408E071-36345
chr3194196429194196557E071-36196
chr3194196612194197352E071-35401
chr3194197365194197565E071-35188
chr3194197584194197868E071-34885
chr3194205365194205405E071-27348
chr3194205505194205570E071-27183
chr3194205644194205735E071-27018
chr3194217327194217439E071-15314
chr3194217561194217646E071-15107
chr3194233477194233624E071724
chr3194233633194234020E071880
chr3194257766194258944E07125013
chr3194261400194261578E07128647
chr3194261788194261828E07129035
chr3194269356194270017E07136603
chr3194270562194270612E07137809
chr3194270759194270824E07138006
chr3194270968194271018E07138215
chr3194271169194271455E07138416
chr3194271547194271609E07138794
chr3194261400194261578E07228647
chr3194269356194270017E07236603
chr3194277127194277633E07244374
chr3194195068194195147E073-37606
chr3194205644194205735E073-27018
chr3194257766194258944E07325013
chr3194269356194270017E07336603
chr3194271547194271609E07338794
chr3194277127194277633E07344374
chr3194190777194191023E074-41730
chr3194191441194191494E074-41259
chr3194191550194191719E074-41034
chr3194191866194191927E074-40826
chr3194197584194197868E074-34885
chr3194215607194216051E074-16702
chr3194269356194270017E07436603
chr3194277127194277633E07444374
chr3194234674194234904E0811921
chr3194269250194269354E08136497
chr3194269356194270017E08136603
chr3194270562194270612E08137809
chr3194275161194275858E08142408
chr3194275882194276175E08143129
chr3194276421194276471E08143668
chr3194277127194277633E08144374
chr3194234674194234904E0821921
chr3194269356194270017E08236603










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr3194206014194207298E067-25455
chr3194207392194209992E067-22761
chr3194206014194207298E068-25455
chr3194207392194209992E068-22761
chr3194206014194207298E069-25455
chr3194207392194209992E069-22761
chr3194206014194207298E070-25455
chr3194206014194207298E071-25455
chr3194207392194209992E071-22761
chr3194206014194207298E072-25455
chr3194207392194209992E072-22761
chr3194206014194207298E073-25455
chr3194207392194209992E073-22761
chr3194206014194207298E074-25455
chr3194207392194209992E074-22761
chr3194206014194207298E081-25455
chr3194206014194207298E082-25455
chr3194207392194209992E082-22761