rs7632766

Homo sapiens
T>C
TBL1XR1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0238 (7140/29950,GnomAD)
C=0199 (5818/29118,TOPMED)
C=0241 (1209/5008,1000G)
C=0240 (924/3854,ALSPAC)
C=0243 (902/3708,TWINSUK)
chr3:177150265 (GRCh38.p7) (3q26.32)
AD
GWASdb2
1   publication(s)
See rs on genome
416 Enhancers around
17 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.177150265T>C
GRCh37.p13 chr 3NC_000003.11:g.176868053T>C

Gene: TBL1XR1, transducin (beta)-like 1 X-linked receptor 1(minus strand)

Molecule type Change Amino acid[Codon] SO Term
TBL1XR1 transcript variant 2NM_001321193.1:c.N/AIntron Variant
TBL1XR1 transcript variant 3NM_001321194.1:c.N/AIntron Variant
TBL1XR1 transcript variant 4NM_001321195.1:c.N/AIntron Variant
TBL1XR1 transcript variant 1NM_024665.5:c.N/AIntron Variant
TBL1XR1 transcript variant X5XM_005247775.2:c.N/AIntron Variant
TBL1XR1 transcript variant X3XM_006713746.1:c.N/AIntron Variant
TBL1XR1 transcript variant X6XM_011513141.1:c.N/AIntron Variant
TBL1XR1 transcript variant X4XM_011513142.2:c.N/AIntron Variant
TBL1XR1 transcript variant X8XM_011513143.2:c.N/AIntron Variant
TBL1XR1 transcript variant X7XM_017007185.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.864C=0.136
1000GenomesAmericanSub694T=0.740C=0.260
1000GenomesEast AsianSub1008T=0.527C=0.473
1000GenomesEuropeSub1006T=0.759C=0.241
1000GenomesGlobalStudy-wide5008T=0.759C=0.241
1000GenomesSouth AsianSub978T=0.870C=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.760C=0.240
The Genome Aggregation DatabaseAfricanSub8726T=0.853C=0.147
The Genome Aggregation DatabaseAmericanSub836T=0.720C=0.280
The Genome Aggregation DatabaseEast AsianSub1604T=0.455C=0.545
The Genome Aggregation DatabaseEuropeSub18482T=0.748C=0.251
The Genome Aggregation DatabaseGlobalStudy-wide29950T=0.761C=0.238
The Genome Aggregation DatabaseOtherSub302T=0.690C=0.310
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.800C=0.199
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.757C=0.243
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs76327660.000973alcohol dependence21314694

eQTL of rs7632766 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs7632766 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3176820385176820687E067-47366
chr3176823389176823521E067-44532
chr3176824141176824335E067-43718
chr3176824529176824645E067-43408
chr3176827511176828009E067-40044
chr3176833241176833281E067-34772
chr3176834083176834159E067-33894
chr3176835542176835596E067-32457
chr3176835919176836007E067-32046
chr3176836136176836250E067-31803
chr3176840095176840255E067-27798
chr3176840301176840459E067-27594
chr3176841694176841898E067-26155
chr3176843826176844144E067-23909
chr3176844243176844364E067-23689
chr3176844372176844503E067-23550
chr3176847488176847605E067-20448
chr3176849720176849983E067-18070
chr3176850017176850074E067-17979
chr3176850124176850356E067-17697
chr3176851774176852577E067-15476
chr3176862654176863455E067-4598
chr3176863640176863819E067-4234
chr3176863903176864048E067-4005
chr3176865575176865940E067-2113
chr3176866917176866967E067-1086
chr3176867049176867128E067-925
chr3176867207176867257E067-796
chr3176867576176867632E067-421
chr3176868066176868618E06713
chr3176868681176869316E067628
chr3176887710176887804E06719657
chr3176887833176887998E06719780
chr3176888131176888413E06720078
chr3176888459176888517E06720406
chr3176891129176891189E06723076
chr3176892296176892534E06724243
chr3176892608176892674E06724555
chr3176892694176892855E06724641
chr3176895529176896106E06727476
chr3176899421176899497E06731368
chr3176900130176900184E06732077
chr3176900206176900599E06732153
chr3176902536176902699E06734483
chr3176902976176903168E06734923
chr3176903644176903777E06735591
chr3176903849176903928E06735796
chr3176904058176904108E06736005
chr3176904382176904436E06736329
chr3176908349176908523E06740296
chr3176908543176909083E06740490
chr3176909094176909470E06741041
chr3176820385176820687E068-47366
chr3176820985176821025E068-47028
chr3176822218176822272E068-45781
chr3176822295176822398E068-45655
chr3176823389176823521E068-44532
chr3176824141176824335E068-43718
chr3176824529176824645E068-43408
chr3176826566176826669E068-41384
chr3176827511176828009E068-40044
chr3176828040176828985E068-39068
chr3176833161176833214E068-34839
chr3176833241176833281E068-34772
chr3176834083176834159E068-33894
chr3176835542176835596E068-32457
chr3176836136176836250E068-31803
chr3176838078176838162E068-29891
chr3176840095176840255E068-27798
chr3176840301176840459E068-27594
chr3176841694176841898E068-26155
chr3176842555176842825E068-25228
chr3176842826176842988E068-25065
chr3176843125176843217E068-24836
chr3176843826176844144E068-23909
chr3176844243176844364E068-23689
chr3176844372176844503E068-23550
chr3176844947176845044E068-23009
chr3176845181176845243E068-22810
chr3176845982176846342E068-21711
chr3176850017176850074E068-17979
chr3176850124176850356E068-17697
chr3176851774176852577E068-15476
chr3176856664176856722E068-11331
chr3176859360176860145E068-7908
chr3176860148176860362E068-7691
chr3176862654176863455E068-4598
chr3176863640176863819E068-4234
chr3176868066176868618E06813
chr3176868681176869316E068628
chr3176869463176869596E0681410
chr3176872906176872965E0684853
chr3176873396176873440E0685343
chr3176887710176887804E06819657
chr3176887833176887998E06819780
chr3176888131176888413E06820078
chr3176888459176888517E06820406
chr3176892296176892534E06824243
chr3176892608176892674E06824555
chr3176892694176892855E06824641
chr3176895529176896106E06827476
chr3176897016176897761E06828963
chr3176898959176899019E06830906
chr3176899421176899497E06831368
chr3176900130176900184E06832077
chr3176900206176900599E06832153
chr3176902976176903168E06834923
chr3176903644176903777E06835591
chr3176903849176903928E06835796
chr3176904058176904108E06836005
chr3176904382176904436E06836329
chr3176905243176905420E06837190
chr3176905421176905525E06837368
chr3176905576176905710E06837523
chr3176905777176905817E06837724
chr3176908543176909083E06840490
chr3176909094176909470E06841041
chr3176823389176823521E069-44532
chr3176824141176824335E069-43718
chr3176824529176824645E069-43408
chr3176826566176826669E069-41384
chr3176827511176828009E069-40044
chr3176835542176835596E069-32457
chr3176835919176836007E069-32046
chr3176840301176840459E069-27594
chr3176841694176841898E069-26155
chr3176842555176842825E069-25228
chr3176844947176845044E069-23009
chr3176845181176845243E069-22810
chr3176845982176846342E069-21711
chr3176851774176852577E069-15476
chr3176855749176855803E069-12250
chr3176859360176860145E069-7908
chr3176860148176860362E069-7691
chr3176862654176863455E069-4598
chr3176863640176863819E069-4234
chr3176863903176864048E069-4005
chr3176864282176864322E069-3731
chr3176866917176866967E069-1086
chr3176867049176867128E069-925
chr3176867207176867257E069-796
chr3176867576176867632E069-421
chr3176868066176868618E06913
chr3176868681176869316E069628
chr3176887710176887804E06919657
chr3176887833176887998E06919780
chr3176891129176891189E06923076
chr3176892296176892534E06924243
chr3176892608176892674E06924555
chr3176892694176892855E06924641
chr3176899421176899497E06931368
chr3176900130176900184E06932077
chr3176900206176900599E06932153
chr3176902536176902699E06934483
chr3176902976176903168E06934923
chr3176903644176903777E06935591
chr3176905243176905420E06937190
chr3176905421176905525E06937368
chr3176905576176905710E06937523
chr3176905777176905817E06937724
chr3176908349176908523E06940296
chr3176908543176909083E06940490
chr3176909094176909470E06941041
chr3176823389176823521E070-44532
chr3176824529176824645E070-43408
chr3176835542176835596E070-32457
chr3176835919176836007E070-32046
chr3176836136176836250E070-31803
chr3176867576176867632E070-421
chr3176868066176868618E07013
chr3176868681176869316E070628
chr3176869463176869596E0701410
chr3176890326176890376E07022273
chr3176891129176891189E07023076
chr3176891571176891611E07023518
chr3176892296176892534E07024243
chr3176892608176892674E07024555
chr3176892694176892855E07024641
chr3176902976176903168E07034923
chr3176903849176903928E07035796
chr3176905243176905420E07037190
chr3176905421176905525E07037368
chr3176905576176905710E07037523
chr3176908543176909083E07040490
chr3176909094176909470E07041041
chr3176820385176820687E071-47366
chr3176823389176823521E071-44532
chr3176824141176824335E071-43718
chr3176824529176824645E071-43408
chr3176825307176825514E071-42539
chr3176827511176828009E071-40044
chr3176828040176828985E071-39068
chr3176831072176831149E071-36904
chr3176833161176833214E071-34839
chr3176833241176833281E071-34772
chr3176834083176834159E071-33894
chr3176835542176835596E071-32457
chr3176835919176836007E071-32046
chr3176836136176836250E071-31803
chr3176841694176841898E071-26155
chr3176842555176842825E071-25228
chr3176842826176842988E071-25065
chr3176843125176843217E071-24836
chr3176843826176844144E071-23909
chr3176844243176844364E071-23689
chr3176844372176844503E071-23550
chr3176845982176846342E071-21711
chr3176849720176849983E071-18070
chr3176850017176850074E071-17979
chr3176850124176850356E071-17697
chr3176851774176852577E071-15476
chr3176859360176860145E071-7908
chr3176860148176860362E071-7691
chr3176860695176860735E071-7318
chr3176862654176863455E071-4598
chr3176863640176863819E071-4234
chr3176863903176864048E071-4005
chr3176864282176864322E071-3731
chr3176864419176864779E071-3274
chr3176865575176865940E071-2113
chr3176868066176868618E07113
chr3176868681176869316E071628
chr3176887710176887804E07119657
chr3176887833176887998E07119780
chr3176888131176888413E07120078
chr3176888459176888517E07120406
chr3176892608176892674E07124555
chr3176892694176892855E07124641
chr3176897928176898008E07129875
chr3176898074176898188E07130021
chr3176898406176898446E07130353
chr3176898461176898553E07130408
chr3176898866176898916E07130813
chr3176898959176899019E07130906
chr3176899421176899497E07131368
chr3176900130176900184E07132077
chr3176900206176900599E07132153
chr3176902536176902699E07134483
chr3176902976176903168E07134923
chr3176903644176903777E07135591
chr3176903849176903928E07135796
chr3176904058176904108E07136005
chr3176904382176904436E07136329
chr3176905243176905420E07137190
chr3176908349176908523E07140296
chr3176908543176909083E07140490
chr3176909094176909470E07141041
chr3176820385176820687E072-47366
chr3176822218176822272E072-45781
chr3176822295176822398E072-45655
chr3176823389176823521E072-44532
chr3176824141176824335E072-43718
chr3176824529176824645E072-43408
chr3176841694176841898E072-26155
chr3176842555176842825E072-25228
chr3176842826176842988E072-25065
chr3176843125176843217E072-24836
chr3176843826176844144E072-23909
chr3176844243176844364E072-23689
chr3176844372176844503E072-23550
chr3176844947176845044E072-23009
chr3176845181176845243E072-22810
chr3176845982176846342E072-21711
chr3176847488176847605E072-20448
chr3176847716176847811E072-20242
chr3176849720176849983E072-18070
chr3176850017176850074E072-17979
chr3176850124176850356E072-17697
chr3176859360176860145E072-7908
chr3176860148176860362E072-7691
chr3176862654176863455E072-4598
chr3176863640176863819E072-4234
chr3176863903176864048E072-4005
chr3176864282176864322E072-3731
chr3176864419176864779E072-3274
chr3176865575176865940E072-2113
chr3176867576176867632E072-421
chr3176868066176868618E07213
chr3176868681176869316E072628
chr3176869463176869596E0721410
chr3176892296176892534E07224243
chr3176892608176892674E07224555
chr3176892694176892855E07224641
chr3176899421176899497E07231368
chr3176900130176900184E07232077
chr3176900206176900599E07232153
chr3176902976176903168E07234923
chr3176903644176903777E07235591
chr3176903849176903928E07235796
chr3176904058176904108E07236005
chr3176904382176904436E07236329
chr3176820385176820687E073-47366
chr3176823389176823521E073-44532
chr3176824141176824335E073-43718
chr3176824529176824645E073-43408
chr3176833161176833214E073-34839
chr3176833241176833281E073-34772
chr3176844243176844364E073-23689
chr3176844372176844503E073-23550
chr3176850017176850074E073-17979
chr3176850124176850356E073-17697
chr3176851774176852577E073-15476
chr3176859360176860145E073-7908
chr3176868066176868618E07313
chr3176868681176869316E073628
chr3176869463176869596E0731410
chr3176887710176887804E07319657
chr3176887833176887998E07319780
chr3176888131176888413E07320078
chr3176888459176888517E07320406
chr3176892296176892534E07324243
chr3176892608176892674E07324555
chr3176892694176892855E07324641
chr3176899421176899497E07331368
chr3176900130176900184E07332077
chr3176900206176900599E07332153
chr3176902536176902699E07334483
chr3176902976176903168E07334923
chr3176908349176908523E07340296
chr3176908543176909083E07340490
chr3176909094176909470E07341041
chr3176820385176820687E074-47366
chr3176823389176823521E074-44532
chr3176824141176824335E074-43718
chr3176824529176824645E074-43408
chr3176825307176825514E074-42539
chr3176826566176826669E074-41384
chr3176827511176828009E074-40044
chr3176828040176828985E074-39068
chr3176829239176829422E074-38631
chr3176833161176833214E074-34839
chr3176833241176833281E074-34772
chr3176834083176834159E074-33894
chr3176835542176835596E074-32457
chr3176841694176841898E074-26155
chr3176842555176842825E074-25228
chr3176843826176844144E074-23909
chr3176844243176844364E074-23689
chr3176844372176844503E074-23550
chr3176845982176846342E074-21711
chr3176847488176847605E074-20448
chr3176849720176849983E074-18070
chr3176850017176850074E074-17979
chr3176850124176850356E074-17697
chr3176851774176852577E074-15476
chr3176859360176860145E074-7908
chr3176860148176860362E074-7691
chr3176860695176860735E074-7318
chr3176862654176863455E074-4598
chr3176863640176863819E074-4234
chr3176863903176864048E074-4005
chr3176866917176866967E074-1086
chr3176867049176867128E074-925
chr3176867207176867257E074-796
chr3176867576176867632E074-421
chr3176868066176868618E07413
chr3176868681176869316E074628
chr3176872276176872330E0744223
chr3176872906176872965E0744853
chr3176887710176887804E07419657
chr3176887833176887998E07419780
chr3176888131176888413E07420078
chr3176888459176888517E07420406
chr3176892296176892534E07424243
chr3176892608176892674E07424555
chr3176892694176892855E07424641
chr3176899421176899497E07431368
chr3176900130176900184E07432077
chr3176900206176900599E07432153
chr3176902536176902699E07434483
chr3176902976176903168E07434923
chr3176908349176908523E07440296
chr3176908543176909083E07440490
chr3176909094176909470E07441041
chr3176823389176823521E081-44532
chr3176841694176841898E081-26155
chr3176842555176842825E081-25228
chr3176842826176842988E081-25065
chr3176843125176843217E081-24836
chr3176843826176844144E081-23909
chr3176844243176844364E081-23689
chr3176844372176844503E081-23550
chr3176850017176850074E081-17979
chr3176850124176850356E081-17697
chr3176851774176852577E081-15476
chr3176867576176867632E081-421
chr3176868066176868618E08113
chr3176868681176869316E081628
chr3176869463176869596E0811410
chr3176891129176891189E08123076
chr3176891571176891611E08123518
chr3176892694176892855E08124641
chr3176904058176904108E08136005
chr3176908349176908523E08140296
chr3176908543176909083E08140490
chr3176909094176909470E08141041
chr3176910237176910311E08142184
chr3176910374176910459E08142321
chr3176823389176823521E082-44532
chr3176824141176824335E082-43718
chr3176824529176824645E082-43408
chr3176835542176835596E082-32457
chr3176843125176843217E082-24836
chr3176843826176844144E082-23909
chr3176851774176852577E082-15476
chr3176862654176863455E082-4598
chr3176863640176863819E082-4234
chr3176863903176864048E082-4005
chr3176867576176867632E082-421
chr3176868066176868618E08213
chr3176868681176869316E082628
chr3176892296176892534E08224243
chr3176892608176892674E08224555
chr3176892694176892855E08224641
chr3176908543176909083E08240490
chr3176909094176909470E08241041










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr3176912455176912754E06744402
chr3176912757176917711E06744704
chr3176912455176912754E06844402
chr3176912757176917711E06844704
chr3176912757176917711E06944704
chr3176912455176912754E07044402
chr3176912757176917711E07044704
chr3176912455176912754E07144402
chr3176912757176917711E07144704
chr3176912455176912754E07244402
chr3176912757176917711E07244704
chr3176912455176912754E07344402
chr3176912757176917711E07344704
chr3176912757176917711E07444704
chr3176912455176912754E08144402
chr3176912455176912754E08244402
chr3176912757176917711E08244704